Eprex 3000IU Injection(Pfs) 0.3ml

Haematopoiesis Rx required
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Best Price*  ₹ 1,112.00
MRP ₹1,390.00
(Inclusive of all taxes) * Mkt: Janssen Pharmaceuticals * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

EPREX 3000IU (PFS) contains Erythropoietin alfa which belongs to a group of medicines called Erythropoiesis-Stimulating agent (ESA). It is used to treat symptomatic anaemia caused by kidney disease (in children on haemodialysis, in adults on haemodialysis or peritoneal dialysis and in severely anaemic adults not yet undergoing dialysis), anaemia in adults receiving chemotherapy for solid tumors. It is also used to treat moderately anaemic adults who donate their blood before surgery, in patients about to have major orthopaedic surgery and anaemia in patients with a bone marrow disorder that causes a severe disruption in the creation of blood cells (myelodysplastic syndromes).

Erythropoietin alfa (epoetin alfa) is a protein that stimulates the bone marrow to produce more red blood cells which carry haemoglobin (a substance that transports oxygen).

This medicine will be administered by your doctor or nurse by intravenous or subcutaneous route. Before receiving EPREX 3000IU (PFS), tell your physician if you have high blood pressure, blood clotting diseases or problems related to liver, kidney and heart. Pregnant and breastfeeding women are recommended to consult the doctor before receiving this medicine. The common side effects are diarrhea, vomiting, headache, redness, burning and pain at the site of injection.

USES OF EPREX 3000IU (PFS)

Treats,

  • anaemia due to kidney disease
  • anaemia in patients receiving chemotherapy for solid tumours

HOW EPREX 3000IU (PFS) WORKS

EPREX 3000IU (PFS) belongs to erythropoiesis-stimulating agents which works by causing the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells.

 

DIRECTIONS FOR USE

EPREX 3000IU (PFS) will be administered intravenously or subcutaneously (under the skin) by your doctor or nurse.

SIDE EFFECTS OF EPREX 3000IU (PFS)

SERIOUS

  • serious skin rashes

COMMON

  • diarrhea
  • feeling sick in stomach
  • vomiting
  • fever
  • stuffy nose and sore throat (respiratory tract congestion)
  • increase in blood pressure
  • headache
  • blood clots
  • feeling confused or having fits
  • chest pain, breathlessness, painful swelling and redness (leg)
  • cough
  • bone or muscle pain
  • flu-like symptoms
  • redness, burning and pain (injection site)
  • arm or leg pain

RARE

  • unusual tiredness, feeling dizzy, breathlessness (Pure red cell Aplasia)
  • increase in levels of small blood cells
  • pain, dark coloured urine or increased sensitivity of the skin to sunlight (porphyria)

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids. Apply a wet or cold cloth on forehead and rest in a quiet, comfortable and dark room.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS can also be used to prevent dehydration.

Vomiting:

Drink clear or ice-cold drinks. Eat light and bland foods. Avoid sweets.

WARNING & PRECAUTIONS

PREGNANCY

Pregnant women, consult your doctor before using EPREX 3000IU (PFS).

BREASTFEEDING

It is not known whether EPREX 3000IU (PFS) is excreted in human milk. Consult your doctor for advice.

KIDNEY

EPREX 3000IU (PFS) should be used with caution in patients with kidney disease. Consult your doctor for advice.

LIVER

EPREX 3000IU (PFS) should be used with caution in patients with liver disease. Consult your doctor for advice.

ALLERGY

Tell your doctor if you are allergic (hypersensitive) to Erythropoietin alfa.

LUNGS

EPREX 3000IU (PFS) should be used with caution in patients with lung disease. Consult your doctor for advice.

HEART DISEASE

EPREX 3000IU (PFS) is not recommended in patients with recent episodes of heart attack or stroke, severe heart disease, severe disorders of the veins and arteries. Consult your doctor for advice.

OTHERS

Tell your doctor before taking this medicine if you,

  • have been diagnosed with Pure Red Cell Aplasia (bone marrow cannot produce enough red blood cells)
  • have high blood pressure
  • cannot have transfusions with own blood
  • are going to have major elective orthopaedic surgery
  • have blood clot
  • are overweight
  • have diabetes
  • have epileptic seizures or fits
  • have anaemia from other causes
  • have porphyria (a rare blood disorder)
  • have cancer
  • have serious skin reactions

Use in pediatrics:

  • Your doctor will administer the right dose depends on your child’s age and body weight.

Use in geriatrics:

  • Dose adjustments may be required for patients with kidney disease, consult your doctor for advice.

INTERACTIONS

A. Drug - Drug interactions:

Tell the doctor about all the medications including prescription, non-prescription and herbal supplements.

  • cyclosporin (used after kidney transplants)
  • iron supplements and other blood stimulants

Overdosage:

  • Tell the doctor or nurse immediately if you think too much EPREX 3000IU (PFS) has been injected.

SYNOPSIS

Drug :   Erythropoietin alfa (epoetin alfa)
Pharmacological Category :   Erythropoiesis-Stimulating Agent (ESA)
Therapeutic Indication :   Anemia due to chemotherapy in patients with cancer, chronic kidney disease
Dosage Forms :   Injection

MORE INFORMATION

  • Keep out of reach of children
  • Store between 2-8°C

FAQs ABOUT EPREX 3000IU (PFS)

What is EPREX 3000IU (PFS) used for?

EPREX 3000IU (PFS) helps your body make more red blood cells.

How do I know if EPREX 3000IU (PFS) is working?

Your doctor will test the blood regularly, at least weekly at the beginning of your treatment.

What should I check before taking EPREX 3000IU (PFS)?

You will be monitored regularly by your doctor while you are taking this medicine.

Can EPREX 3000IU (PFS) affect blood pressure?

Yes. During initial therapy, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure.

REFERENCES

1. KD Tripathi MD. Haematinics and Erythropoietin. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 611.

2. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page -1071-1072.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 479-481.

4. Janssen-Cilag Ltd. Electronic Medicines Compendium (EMC); [Revised on March, 2021] [Accessed on Sep 25, 2021] https://www.medicines.org.uk/emc/files/pil.3442.pdf

5. Janssen Products, LP. Amgen Inc. [Revised on May, 2012] [Accessed on Sep 25, 2021] https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/PROCRIT-pi.pdf

6. Ortho Biotech Products, L.P. Amgen Inc. U.S. Food & Drug Administration; [Revised on Aug, 2008] [Accessed on Sep 25, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/103234s5196pi.pdf  

7. Drugs.com. Epoetin Alfa. [Revised on June 02, 2020] [Accessed on Sep 25, 2021] https://www.drugs.com/ppa/epoetin-alfa.html

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count
  • Peripheral Smear Examination

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    25 g
    Ingredient
    ERYTHROPOIETIN 3000IU
    Hsn Code
    30045010
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