EPLERIGO 25 Tablet 10's

Hypertension Rx required

Best Price* ₹ 290.72 MRP ₹ 363.40
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

EPLERIGO 25 contains Eplerenone, which belongs to the group of medicines called Selective Aldosterone blocking agents. It is used for the treatment of mild to moderate hypertension (condition in which the force of the blood against the artery walls is too high) and heart failure in adults. Heart failure is a chronic condition in which the heart doesn't pump blood properly to meet the body’s demand.

EPLERIGO 25 is not recommended for use in patients with severe liver disease, severe kidney disease, or high potassium levels in the blood etc. It should be used with caution in patients with other kidney or liver diseases etc. Consult your doctor before taking EPLERIGO 25. Before taking EPLERIGO 25 inform your doctor if you are pregnant or planning to get pregnant or breast-feeding women.

EPLERIGO 25 is not recommended for use in children and growing adults. It should be used with caution in elderly patients. Consult your doctor before taking EPLERIGO 25. The most common side effects of taking EPLERIGO 25 are nausea, vomiting, diarrhoea, constipation, high potassium level, low blood pressure, fainting, dizziness, headache etc. Consult your doctor if any of the symptom worsens.

USES OF EPLERIGO 25

  • Treats mild to moderate hypertension
  • Treats heart failure

HOW EPLERIGO 25 WORKS

EPLERIGO 25 works by inhibiting the action of aldosterone, a hormonal substance produced within the body that controls blood pressure and heart function. As a result, it effectively regulates blood pressure and improves heart function.

DIRECTIONS FOR USE

Take EPLERIGO 25 as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF EPLERIGO 25

COMMON

  • elevated potassium levels in the blood (symptoms include muscle cramps, diarrhoea, nausea, dizziness or headache)  
  • fainting, dizziness
  • insomnia (difficulty sleeping)
  • headache  
  • irregular heartbeat  
  • cough  
  • low blood pressure
  • nausea, vomiting
  • diarrhoea, constipation  
  • abnormal functioning of your kidney  
  • rash, itching
  • back pain
  • feeling weak
  • muscle spasm

UNCOMMON

  • infection
  • eosinophilia (increase in certain white blood cells)
  • low sodium blood levels
  • dehydration
  • elevated triglycerides (fats) levels in the blood
  • fast heartbeat
  • inflammation of the gall bladder
  • decreased blood pressure upon standing causing dizziness
  • thrombosis (blood clot) in the leg
  • sore throat
  • flatulence
  • underactive thyroid
  • increase in blood glucose levels
  • reduced sense of touch  
  • increased sweating
  • musculoskeletal pain
  • feeling generally unwell  
  • kidney inflammation
  • enlargement of breasts in men

Stop taking EPLERIGO 25 and contact your doctor immediately if you experience any of the following side effects:

  • angioneurotic oedema symptoms such as a swollen face, tongue or throat, difficulty swallowing, hives and difficulties breathing

HOW TO MANAGE SIDE EFFECTS

Headache:

Take rest and relax. Drink plenty of fluids such as water or fruit juices. Apply a pain-relieving balm on the forehead if necessary. Consult your doctor if the symptom does not improve.

Nausea and vomiting:

Take EPLERIGO 25 with or just after a meal. Stick to simple meals. Avoid eating oily or spicy foods. Do not lie down immediately after eating. Consult your doctor if the symptom does not improve.  

Diarrhoea:

Drink lot of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for treating diarrhoea. Consult your doctor if the symptom does not improve.

Constipation:

Eat plenty of fiber-rich foods in your diet such as fresh fruits, vegetables, and cereals. Drink plenty of water and exercise more regularly. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until dizziness passes away and then move slowly and carefully. Take rest and drink plenty of fluids. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

EPLERIGO 25 should be used with caution in pregnant women. Inform your doctor, if you are pregnant or think you may be pregnant or planning to have a baby. Consult your doctor before taking EPLERIGO 25.

BREASTFEEDING

It is not known whether EPLERIGO 25 is excreted in human breast milk. Consult your doctor before taking EPLERIGO 25.

DRIVING AND USING MACHINES

Do not drive or operate any machinery if you feel dizzy after taking EPLERIGO 25.

KIDNEY

EPLERIGO 25 is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with other kidney diseases. Consult your doctor before taking EPLERIGO 25.

LIVER

EPLERIGO 25 is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver diseases. Consult your doctor before taking EPLERIGO 25.

ALLERGY

Do not take EPLERIGO 25 if you are allergic to Eplerenone or any of the other ingredients of this medicine.

OTHERS

EPLERIGO 25 is not recommended for use if you have:

  • high levels of potassium in the blood (hyperkalemia)

Use in pediatrics:

EPLERIGO 25 is not recommended for use in children and growing adults. Consult child’s doctor for advice.

Use in geriatrics:

EPLERIGO 25 should be used with caution in elderly patients. Consult your doctor before taking EPLERIGO 25.

INTERACTIONS

A. Drug - Drug interactions:

Before taking EPLERIGO 25, inform your doctor if you are taking any of the following medicines:

  • itraconazole, ketoconazole and fluconazole (used to treat fungal infections)
  • ritonavir, nelfinavir and saquinavir (used to treat HIV infection)
  • clarithromycin, telithromycin, trimethoprim, erythromycin and rifampicin (used to treat bacterial infections)  
  • nefazodone and tricyclic antidepressants like amitriptyline, and amoxapine (used to treat depression)  
  • potassium-sparing diuretics such as spironolactone (used to treat high blood pressure)
  • potassium supplements (salt tablets) (used to increase potassium levels in the blood)
  • angiotensin converting enzyme (ACE) inhibitors such as lisinopril, ramipril and angiotensin receptor blockers (ARB) such as losartan, olmesartan (used to treat high blood pressure, heart disease or some kidney conditions)
  • lithium (used to treat bipolar disorder)
  • cyclosporine or tacrolimus (used to treat skin diseases such as psoriasis or eczema and prevent rejection after organ transplantation)
  • non-steroidal anti-inflammatory drugs such as ibuprofen (used to relieve pain and inflammation)
  • alpha blockers such as prazosin or alfuzosin (used to treat high blood pressure and particular prostate conditions)
  • antipsychotics such as chlorpromazine or haloperidol (used to treat psychiatric disorders)
  • amifostine (used to protect kidneys during cancer treatment)
  • baclofen (used to treat muscle spasms)
  • glucocorticoids Ex. hydrocortisone or prednisone (used to treat inflammation and certain skin conditions)
  • tetracosactide (used to treat disorders of the adrenal cortex)
  • digoxin (used to treat heart conditions)
  • warfarin (used to prevent and treat blood clots)
  • amiodarone, diltiazem and verapamil (used to treat heart problems and high blood pressure)
  • st. john's wort (herbal medicine used to treat depression),
  • medicines used to treat seizures (Ex. carbamazepine, phenytoin, and phenobarbital)

Overdosage:

If you or anyone else accidentally takes too much of EPLERIGO 25, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include low blood pressure (causing light-headedness, dizziness, blurred vision, weakness, acute loss of consciousness) or high levels of potassium in the blood (signs include muscle cramps, diarrhoea, nausea, dizziness or headache).

SYNOPSIS

Drug :   Eplerenone
Pharmacological Category :   Selective aldosterone blocking agents
Therapeutic Indication :  

Hypertension, Heart failure

Dosage Forms :   Tablet

MORE INFORMATION

  • Keep EPLERIGO 25 out of reach of children
  • Store at room temperature

FAQs ABOUT EPLERIGO 25

How does EPLERIGO 25 work?

EPLERIGO 25 works by inhibiting the action of aldosterone, a hormonal substance produced within the body that controls blood pressure and heart function. As a result, it effectively regulates blood pressure and improves heart function.

Is EPLERIGO 25 safe to use in patients with liver disease?

EPLERIGO 25 is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver diseases. Consult your doctor before taking EPLERIGO 25.

Can EPLERIGO 25 cause dizziness?   

Yes, this medicine may cause dizziness in some individuals. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines if you feel dizzy after taking EPLERIGO 25. Do not consume alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve or gets worse.

What is EPLERIGO 25 used for?

EPLERIGO 25 is used to treat mild to moderate hypertension (condition in which the force of the blood against the artery walls is too high) and heart failure in adults. Heart failure is a chronic condition in which the heart doesn't pump blood properly to meet the body’s demand.           

Is EPLERIGO 25 safe to use in patients with kidney disease?

EPLERIGO 25 is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with other kidney diseases. Consult your doctor before taking EPLERIGO 25.

REFERENCES

1. KD Tripathi. Diuretics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page-589.

2. Jennifer Craft. Eplerenone (Inspra), a new aldosterone antagonist for the treatment of systemic hypertension and heart failure. NIH. National Library of Medicine. National Center center of biotechnology Information. PMC Pubmed Central. April 2004. [Accessed on June 3rd 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200656/

3. Faiez Zannad, John J V McMurray, Henry Krum, Dirk J van Veldhuisen, Karl Swedberg, Harry Shi, John Vincent, Stuart J Pocock, Bertram Pitt, EMPHASIS-HF Study Group. Eplerenone in patients with systolic heart failure and mild symptoms. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2011. [Accessed on June 3rd 2022] https://pubmed.ncbi.nlm.nih.gov/21073363/

4. Central Drugs Standard Control Organisation (CDSCO). Eplerenone Tablet (25mg/50mg). [Accessed on June 3rd 2022] https://cdscoonline.gov.in/CDSCO/Drugs

5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on June 3rd 2022] https://www.medicines.org.uk/emc/files/pil.7055.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test
  • Liver function test
  • Electrocardiogram (ECG)

VIDEOS

Eplerenone Tablet - Drug Information

Eplerenone Tablet : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS

    Country Of Origin
    India
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ALTERNATE BRANDS
EPLERITE 25 Tablet 10's
Prescription Hypertension Rx required
Out of stock
Rs.180.00
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

EPLERIGO 25 Tablet 10's

EPLERIGO 25 Tablet 10's Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED

M.R.P.: Rs.363.40
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