Best Price* ₹ 312.00 MRP ₹ 390.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Icarus Health Care Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

ENSAME 200MG TABLET contains S-Adenosyl-L-Methionine which belongs to the group of medicines called Amino acid derivatives. It is used to treat liver problems such as intrahepatic cholestasis (ICP; block in bile flow), liver cirrhosis, hepatitis and alcoholic liver disease in adults.

It can also be used to treat ICP of pregnancy and can reduce the fatigue caused by chronic liver problems. It also helps to reduce joint pain (osteoarthritis), fibromyalgia (severe muscle pain with memory and mood problems), anxiety, depression and other mental illnesses.

Before taking ENSAME 200MG TABLET inform your doctor if you have any kidney problems. You must also inform your doctor if you have bipolar disorder or a previous history of suicidal thoughts as a precaution.

Vitamins such as folic acid and vitamin B12 are essential to enhance the effects of S-Adenosyl-L-Methionine in your body. Therefore, inform your doctor if you have any vitamin deficiencies or anemia as a precaution. You doctor may advise you to take B-vitamin supplements (folic acid and vitamin B12) along with this medicine.

During treatment with ENSAME 200MG TABLET your doctor will routinely monitor the levels of ammonia, folic acid and vitamin B12 in your blood as a precaution and adjust the dose accordingly.

Do not take ENSAME 200MG TABLET without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of taking ENSAME 200MG TABLET are nausea, stomach pain and diarrhea. Consult your doctor if they trouble you.

USES OF ENSAME 200MG TABLET

It is used in adults to treat:

  • intrahepatic cholestasis (ICP) in patients with or without liver disease
  • intrahepatic cholestasis during pregnancy
  • liver diseases (liver cirrhosis, hepatitis and alcoholic liver disease)
  • fatigue caused due to chronic liver problems
  • anxiety, depression and other mental illnesses
  • osteoarthritis (joint pain)
  • fibromyalgia (severe muscle pain causing memory and mood changes)

HOW ENSAME 200MG TABLET WORKS

ENSAME 200MG TABLET protects your liver against various toxins (free radicals) and helps your liver to function normally. It improves the levels of glutathione (an antioxidant) in the liver which helps in preventing further liver cell damage.

It also increases the levels of certain chemical messengers (such as dopamine, noradrenaline, adrenaline, serotonin, melatonin) in the brain that can stabilize mood and mental health. It can also reduce the production of certain chemicals in the body that causes pain and inflammation.

DIRECTIONS FOR USE

Take ENSAME 200MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. It is preferably taken before meals.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ENSAME 200MG TABLET

COMMON

  • Nausea
  • Stomach pain
  • Diarrhea
  • Bloating
  • Stomach discomfort

RARE

Stop taking ENSAME 200MG TABLET and consult your doctor immediately if you experience any of the following side effects:

  • signs of serotonin syndrome (such as feeling agitated, hallucinations, confusion, loss of consciousness, fast heartbeat, feeling dizzy, increased sweating, flushing, tremors, stiff muscles or muscle twitching, loss of coordination, nausea, vomiting, diarrhea or seizures)
  • signs of allergic reactions (such as skin rash, swelling of the hands, face, tongue, neck or throat, increased fluid in tissues, fast heart rate, difficulty in breathing)
  • worsening of depression

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Take this medicine with or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Contact your doctor if nausea worsens.

Diarrhoea:

Drink fluids, such as water or fruit juice in enough quantity to keep yourself hydrated. Don’t take any medicine on your own for treating diarrhoea without talking to your doctor. Contact your doctor if diarrhoea worsen.

WARNING & PRECAUTIONS

PREGNANCY

ENSAME 200MG TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

BREASTFEEDING

ENSAME 200MG TABLET is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if you experience dizziness after taking ENSAME 200MG TABLET as a precaution.

KIDNEY

ENSAME 200MG TABLET should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.

ALLERGY

Do not take ENSAME 200MG TABLET if you are allergic to S-Adenosyl-L-Methionine.

OTHERS

ENSAME 200MG TABLET is not recommended for use if you:

  • have bipolar disease (alternative episodes of happiness and sadness)

Before taking ENSAME 200MG TABLET, inform your doctor if you:

  • have anemia (low RBC in blood)
  • have vitamin B12 or folic acid deficiency
  • have a previous history of suicidal thoughts

Use in pediatrics:

The safety and effectiveness of ENSAME 200MG TABLET have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

Use in geriatrics:

ENSAME 200MG TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking ENSAME 200MG TABLET, inform your doctor if you are taking any of the following medicines such as:

  • other medicines used to treat depression (Ex. phenelzine, iproniazid, isocarboxazid, nialamide, tranylcypromine, moclobemide, fluoxetine, paroxetine, clomipramine, amitriptyline, imipramine etc.)
  • levodopa (a medicine used to treat Parkinson’s disease)
  • tryptophan (an amino acid used to induce sleep)

Overdosage:

If you or anyone else accidentally took more ENSAME 200MG TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   S-Adenosyl-L-Methionine
Pharmacological Category :   Amino acid Derivatives
Therapeutic Indication :   Liver disease, Depression, Osteoarthritis
Dosage Forms :   Tablet, Capsule

MORE INFORMATION

  • Keep ENSAME 200MG TABLET out of sight and reach of children
  • Store ENSAME 200MG TABLET below 25°C

FAQs ABOUT ENSAME 200MG TABLET

What is the use of ENSAME 200MG TABLET?

ENSAME 200MG TABLET is used to treat liver problems such as intrahepatic cholestasis (ICP; block in bile flow), liver cirrhosis, hepatitis and alcoholic liver disease in adults. It can also be used to treat ICP of pregnancy and can reduce the fatigue caused by chronic liver problems. It also helps to reduce joint pain (osteoarthritis), fibromyalgia (severe muscle pain with memory and mood problems), anxiety, depression and other mental illnesses.

Can [GBNKEWORD] reduce liver damage?

Yes. ENSAME 200MG TABLET protects your liver against various toxins (free radicals) and helps your liver to function normally. It also improves the levels of glutathione (an antioxidant) in the liver which helps in preventing further liver cell damage.

What is the best time to take ENSAME 200MG TABLET?

Take ENSAME 200MG TABLET approximately at the same time each day. You can take ENSAME 200MG TABLET either in the morning or in the evening as per doctor’s instructions. Taking it at the same time each day will have the best effect and it would also help you remember your daily dose.

Can ENSAME 200MG TABLET be used to reduce anxiety?

ENSAME 200MG TABLET has been shown to reduce anxiety. It works by increasing the levels of certain chemicals within the brain that controls mood and mental health.

How does ENSAME 200MG TABLET works?

ENSAME 200MG TABLET protects your liver against various toxins (free radicals) and helps your liver to function normally. It also increases the levels of certain chemical messengers (such as dopamine, noradrenaline, adrenaline, serotonin, melatonin) in the brain that can stabilize mood and mental health. It can also reduce the production of certain chemicals in the body that causes pain and inflammation.

Can ENSAME 200MG TABLET be used in children?

The safety and effectiveness of ENSAME 200MG TABLET have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

What to do if I forget to take a dose of ENSAME 200MG TABLET?

If you forget to take a dose of ENSAME 200MG TABLET, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of ENSAME 200MG TABLET to compensate a missed dose, as it could lead to toxicity.

Will taking a higher dose of ENSAME 200MG TABLET than the prescribed one be beneficial?

No, taking a higher dose of ENSAME 200MG TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Can ENSAME 200MG TABLET be taken daily?

Yes. ENSAME 200MG TABLET can be taken daily as per your doctor’s instruction. However, if you are doubtful, consult your doctor.

Can ENSAME 200MG TABLET be used in pregnant women?

ENSAME 200MG TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

How to take ENSAME 200MG TABLET?

Take ENSAME 200MG TABLET as advised by your physician. It is preferably taken before meals. Swallow the medicine with a glass of water. Do not chew or crush the medicine.

Can I stop taking ENSAME 200MG TABLET once I started feeling better?

Do not stop taking ENSAME 200MG TABLET without consulting your doctor as it may make your symptoms re-appear

What are the side effects of ENSAME 200MG TABLET?

The most common side effects of taking ENSAME 200MG TABLET are nausea, stomach pain and diarrhoea. Consult your doctor if they trouble you.

Is ENSAME 200MG TABLET safe?

ENSAME 200MG TABLET is safe at doses prescribed by the doctor. Do not alter the dosage of ENSAME 200MG TABLET without consulting your doctor.

REFERENCES

1. Harsh Mohan. The Liver, Biliary Tract and Exocrine Pancreas. Textbook of Pathology. 6th Edition. 2010. Page – 599.

2. Anup Sharma, MD, PhD, Patricia Gerbarg, MD, Teodoro Bottiglieri, PhD, Lila Massoumi, MD, Linda L. Carpenter, MD, Helen Lavretsky, MD, Philip R. Muskin, MD, Richard P. Brown, MD and David Mischoulon, MD, PhD. S-Adenosylmethionine (SAMe) for neuropsychiatric disorders: A Clinician-Oriented Review of Research. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. December 2017. [Accessed on 25th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501081/

3. AbbVie S.r.L. Abbott Laboratories. Ademetionine butanedisulfonate (Transmetil). [Accessed on 25th November 2022] https://www.medicine.abbott/content/dam/bss/divisionalsites/epd/productpdf/Transmetil%20500mg.pdf

4. La Renon Healthcare Private Limited. Methosam. Ademetionine Enteric Coated Tablets 200mg. [Accessed on 25th November 2022] https://www.larenon.com/wp-content/uploads/2022/04/METHOSAM-LBL-Depression.pdf

5. La Renon Healthcare Private Limited. Cirrosam. Ademetionine Enteric Coated Tablets 400mg. [Accessed on 25th November 2022] https://www.larenon.com/wp-content/uploads/2022/04/Cirrosam-LBL.pdf

6. La Renon Healthcare Private Limited. CIRROSAM (S-Adenosyl L-Methionine 400 mg tablets). [Accessed on 25th November 2022] https://www.larenon.com/wp-content/uploads/2020/06/cirrosam-lbl_Final.pdf

7. Abbott. Heptral 200/400. MIMS.com. [Accessed on 25th November 2022] https://www.mims.com/singapore/drug/info/heptral%20200-400?type=full

8. Central Drug Standard Control Organisation (CDSCO). Ademetionine enteric coated Tablets.200mg/400mg. [Revised in September 2010] [Accessed on 25th November 2022] https://cdscoonline.gov.in/CDSCO/Drugs

9. Leeford Healthcare. Lesamy 200. [Accessed on 25th November 2022] https://www.leeford.in/product/715/lesamy-200

USEFUL DIAGNOSTIC TESTS

  • Liver function test
  • Bilirubin Direct
  • Bilirubin indirect
  • Bilirubin Total

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    S-ADENOSYL METHIONINE(ADEMETIONINE) 200MG
    Hsn Code
    21069099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Ensame 200mg Tablet 10'S

Ensame 200mg Tablet 10'S Mkt: Icarus Health Care Pvt Ltd

M.R.P.: Rs.390.00
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