INTRODUCTION

ENPRED contains Difluprednate which belongs to a group of medicines called Corticosteroids. It is used to treat inflammation and pain associated with cataract surgery and endogenous anterior uveitis (inflammation in the middle part of the eye).

Corticosteroid inhibits the inflammatory response to a variety of inciting agents and may delay or slow healing. It also inhibits edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation.

Before using ENPRED inform your doctor if you have liver, kidney or heart problems, are pregnant or breastfeeding. The common side effects are burning sensation, eye irritation and watery eyes. Avoid touching your eyelids or surrounding areas with the dropper tip of the bottle.  If you wear contact lenses, remove them before using this medicine, do not wear a contact lens if your eye is red.

USES OF ENPRED

• Treats inflammation and pain associated with cataract surgery and endogenous anterior uveitis (inflammation in the middle part of the eye)

HOW ENPRED WORKS

ENPRED stimulates the production of certain proteins that prevents the production of other substances that are part of the inflammatory process and reduces the pain and inflammation of cataract surgery and uveitis.

DIRECTIONS FOR USE

Always use ENPRED as instructed by your doctor. Keep bottle tightly closed when not in use.

• Wash your hands and tilt your head back and look at the ceiling
• Gently pull the lower eyelid to make a small pocket
• Turn the bottle upside down and squeeze it smoothly to release one drop into the eyelid pocket
• If you need to use medicine in both eyes, repeat the steps for your other eye

SIDE EFFECTS OF ENPRED

HOW TO MANAGE SIDE EFFECTS

Eye irritation:
Place a cold cloth above your closed eyes two to three times a day for five minutes.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your physician if you are taking,

• ritonavir or cobicistat (used to treat HIV/AIDS)
• NSAIDs

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ENPRED

How does ENPRED works?

It stimulates the production of certain proteins that prevents the production of other substances that are part of the inflammatory process and reduces the pain and inflammation of cataract surgery and uveitis.

Can I wear contact lenses while using this ENPRED?

No, do not wear contact lenses prior to administration and wait at least 15 minutes after instilling the medicine.

Is ENPRED effective?

This medicine is effective if used in the dose and duration as directed by your doctor.

REFERENCES

1. Eric D Donnenfeld. Difluprednate for the prevention of ocular inflammation postsurgery: an update. June 15, 2011. [Accessed on June 23, 2021] https://pubmed.ncbi.nlm.nih.gov/?term=Donnenfeld%20ED%5BAuthor%5D&cauthor=true&cauthor_uid=21750615

2. Charu Mithal, Shilpa Singh, Sonali Gupta, Sandeep Mithal. Difluprednate: An Overview. Sep 25, 2013. [Accessed on June 23, 2021] https://www.djo.org.in/articles/23/3/difluprednate-an-overview.html

3. Novartis Pharmaceuticals Canada Inc. [Revised on July 19, 2018] [Accessed on June 23, 2021] Durezol - Novartis Pharmaceuticals Corporationhttps://www.novartis.us › www.novartis.us › files PDF