ENDACE 160mg Tablet is primarily used for the treatment of breast cancer and endometrial cancer. It is also used as a supportive therapy for anorexia and cachexia (muscle wasting).

ENDACE 160mg Tablet may also be prescribed for other conditions as determined by the doctor.

ENDACE 160mg Tablet belongs to the class of drugs called hormonal agents. This drug is a potent agonist of progesterone that acts by lowering the levels of oestrogen in the body, which inhibits the cancer growth stimulated by oestrogen.

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take ENDACE 160mg Tablet as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of ENDACE 160mg Tablet, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of ENDACE 160mg Tablet may include:

• Chest pain
• Shortness of breath
• Unsteady gait

Drugs that interact with ENDACE 160mg Tablet include the following:

• Acarbose
• Acetaminophen
• Aspirin
• Atropine
• Clarithromycin
• Cyclosporine
• Guaifenesin
• Phenobarbital
• Thalidomide

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

The following are the most common side effects of ENDACE 160mg Tablet:

• Weight gain
• Fluid retention
• Hot flashes
• Weakness
• Rash
• Sweating

The following are the severe side effects, and you may require immediate medical attention:

• Vaginal bleeding
• Anaemia
• Hyperglycaemia
• Hypertension
• Insomnia

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

• Avoid using the medicine if you are allergic to ENDACE 160mg Tablet or similar drugs.
• Avoid ENDACE 160mg Tablet during pregnancy or breastfeeding because the safe use of the drug is unknown.
• Do not stop using the medication abruptly unless instructed by the doctor.
• Do not exceed the dose more than prescribed.

You are advised not to take ENDACE 160mg Tablet if

• it has passed the expiry date of the medicine printed on the pack.
• the foil or packaging is torn or shows signs of tampering or there is discolouration.

• Tell your doctor if you have any history of heart, liver, kidney or respiratory diseases.
• Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• Inform the doctor if you are pregnant or breastfeeding.

1. How should ENDACE 160mg Tablet be stored?

ENDACE 160mg Tablet should be stored at room temperature, in a cool and dry place.

2. Do I need to be monitored for any laboratory parameters while taking ENDACE 160mg Tablet?

Physical examination, blood electrolyte levels, blood sugar levels and heart function tests must be regularly monitored while using ENDACE 160mg Tablet.

3. Is it safe to use ENDACE 160mg Tablet in diabetic patients?

No. It is not safe to use ENDACE 160mg Tablet in diabetic patients, as the drug may further increase the blood sugar levels.

4. What are the other formulations of ENDACE 160mg Tablet available?

ENDACE 160mg Tablet is available as a tablet and oral suspension.