Encorate 500mg Tablet 10'S

Epilepsy/Convulsion Rx required

Best Price*  ₹ 62.22
MRP ₹77.78
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Sun Pharmaceutical Industries Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

ENCORATE 500MG contain Sodium valproate which belongs to a group of medicine called anti-convulsant or anti-epileptic agents. This medicine is used to treat epilepsy (fits) in adults and children. Epilepsy may occur as a result of a genetic disorders or an acquired brain injury such as a trauma or stroke, in which nerve cells activity in the brain is disturbed, causing seizures. It control seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

It must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effects are nausea, vomiting, stomach ache, diarrhoea, double vision, hair loss, weight gain, headache, loss of appetite, tremor.

USES OF ENCORATE 500MG

  • Treat epilepsy (fits) in adults and children

HOW ENCORATE 500MG WORKS

ENCORATE 500MG control seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

DIRECTIONS FOR USE

Always take ENCORATE 500MG exactly as your doctor has told you. This medicine must be taken with or without food. The dose is normally split and given half in the morning and half in the evening. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF ENCORATE 500MG

COMMON

  • nausea, vomiting, stomachache or diarrhoea
  • swelling of gums or sore mouth
  • fainting
  • hearing loss
  • double vision
  • nail and nail bed disorders
  • skin problems such as rashes
  • hair disorders (changes in texture, colour, or growth), hair loss
  • increased levels of some hormones (androgen), which may lead to increased hair growth on the face, breasts or chest, acne, or thinning hair
  • change in women’s periods and increased hair growth in women
  • breast enlargement in men
  • swelling of the feet and legs (oedema)
  • obesity, weight gain
  • headache
  • hallucinations
  • aggression, agitation, disturbance in attention, abnormal behaviour, restlessness/hyperactivity, and learning disorder
  • tingling or numbness in the hands and feet
  • lowering of normal body temperature
  • abnormal blood clotting factors
  • muscle pain and weakness (rhabdomyolysis)
  • bone disorders such as osteopenia and osteoporosis
  • change levels of liver enzymes
  • male infertility

RARE

  • allergic reaction (including rash, joint pain, fever, swallowing or breathing problems, swelling of your lips, face, throat, or tongue)
  • liver problems and problems of the pancreas
  • jaundice (yellowing of the skin or white of the eye)
  • loss of appetite
  • worsening of your fits or general feeling of being unwell
  • blistering or bleeding of the skin around the lip, eye, mouth, nose, and genital, flu-like symptoms, and fever (Stevens-Johnson syndrome)
  • severe blistering rash where layers of the skin may peel off to leave large areas of raw exposed skin over the body, feeling of being generally unwell, fever, chills, and aching muscles (Toxic epidermal necrolysis)
  • bruising more easily and getting more infections than usual(thrombocytopenia). Fall in the number of white blood cell, bone marrow depression or another condition that affect red blood cell, white blood cell and platelet (pancytopenia)
  • blood clotting problems
  • change in mood, loss of memory, lack of concentration and deep loss of consciousness (coma)
  • underactive thyroid gland
  • breathing difficulty and pain due to inflammation of the lung (pleural effusion)
  • change in the amount of ammonia in the blood
  • tremor
  • rapid, uncontrollable movement of the eyes
  • increase in the number and severity of convulsion

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Stomach pain:

Try to rest and relax. Eat and drink slowly or have smaller and frequent meal. Applying heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Diarrhoea:

Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Fever:

Drink plenty of fluids and water. Avoid taking cold baths or showers.

WARNING & PRECAUTIONS

PREGNANCY

ENCORATE 500MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

ENCORATE 500MG should be used with caution in breast feeding women. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machine while taking this medicine since it may cause sleepiness.

ALCOHOL

Consumption of alcohol is not recommended during treatment with ENCORATE 500MG.

KIDNEY

ENCORATE 500MG should be used with caution in patients suffering from active kidney diseases. Before taking, this medicine consult your doctor for advice.

LIVER

ENCORATE 500MG is not recommended in patients with active liver diseases. Before taking, this medicine consult your doctor for advice.

ALLERGY

Do not take ENCORATE 500MG if you are allergic (hypersensitive) to sodium valproate or any other ingredients in this medicine.

OTHERS

Tell your doctor if you have or had a condition such as,

  • rare illness called porphyria
  • metabolic disorder (urea cycle disorder)
  • genetic problem caused by a mitochondrial disorder (Alpers-Huttenlocher syndrome)
  • diabetes
  • carnitine palmitoyltransferase type II deficiency
  • brain disease or a metabolic condition affecting your brain
  • illness called systemic lupus erythematosus (SLE)

INTERACTIONS

Talk to your doctor if you are taking,

  • salicylates such as aspirin (used to treat pain and inflammation)
  • phenobarbital, primidone, phenytoin, carbamazepine, rufinamide, topiramate, acetazolamide, lamotrigine and felbamate (used to treat fits (epilepsy))
  • warfarin (used for thinning the blood)
  • zidovudine, protease inhibitor such as lopinavir and ritonavir (used to treat HIV infection and AIDS)
  •  temozolomide (used to treat cancer)
  • monoamine oxidase inhibitor (MAOI) such as moclobemide, selegiline, linezolid (used to treat depression)
  • quetiapine, diazepam, and olanzapine (used to treat schizophrenia, bipolar disorder, and depression)
  • nimodipine
  • propofol (used for anaesthesia)
  • oestrogen-containing products including some birth control pills
  • mefloquine and chloroquine (used to prevent and treat malaria)
  • cimetidine (used to treat stomach ulcers)
  • carbapenem agents such as imipenem, meropenem, rifampicin and erythromycin (used to treat bacterial infections)
  • cholestyramine (used to lower blood fat level)

SYNOPSIS

Drug :   Valproic acid
Pharmacological Category :   Anticonvulsant, anti-epileptic agents
Therapeutic Indication :  

Epilepsy (fits)

Dosage Forms :   Tablet, Capsule, Injection, Oral solution

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ENCORATE 500MG

Can I drink alcohol while taking ENCORATE 500MG?

No, Consumption of alcohol is not recommended during treatment with this medicine.

Is it safe to drive or operate heavy machinery when consuming ENCORATE 500MG?

No, do not drive or operate any machine while taking this medicine since it may cause sleepiness.

Can I take ENCORATE 500MG during pregnancy?

No, it is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

REFERENCES

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 4053-4069.

2. Natalia N Nalivaeva 1, Nikolai D Belyaev, Anthony J Turner. Sodium valproate: an old drug with new roles. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Oct 2009. [Accessed 04 Dec 2020] https://pubmed.ncbi.nlm.nih.gov/19762089/

3. Peter M. Jeavons and Jean E. Clark. Sodium Valproate in Treatment of Epilepsy. US National Library of Medicines, National Institutes of Health. 15 Jun 1974. [Accessed 04 Dec 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1610767/

4. Sanofi-aventis S.A; Electronic Medicines Compendium (EMC); [Revised on Nov 2019] [Accessed 04 Dec 2020] https://www.medicines.org.uk/emc/files/pil.519.pdf

USEFUL DIAGNOSTIC TESTS

  • EEG
  • MRI Scan
  • CT Scan

VIDEOS

SODIUM VALPROATE TABLET - Drug Information

SODIUM VALPROATE TABLET : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    17.5
    Ingredient
    SODIUM VALPROATE 500MG
    Hsn Code
    30049082
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Encorate 500mg Tablet 10'S

Encorate 500mg Tablet 10'S Mkt: Sun Pharmaceutical Industries Ltd

M.R.P.: Rs.77.78
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