INTRODUCTION

EMPROGEST 100MG contains Progesterone which belongs to the group of medicine called progestins. It is used to treat amenorrhea (lack of periods) and abnormal uterine bleeding due to hormonal imbalance without any underlying disease conditions such as submucous fibroids or uterine cancer. Progesterone helps to maintain hormonal balance and provides relief from menstrual disorders and infertility issues. Along with the treatment, your doctor might recommend you to, eat healthy diet rich in fruits, greens and vegetables. Try to exercise regularly and reduce your stress levels. If you are over-weight or obese, reduce your extra weight, which might help you see the results faster.

This medicine will be administered to you only by a doctor or a nurse into the muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. The most common side effects of taking this medicine are dizziness, injection site reactions breast pain, nausea, vomiting, edema or headaches. Contact your doctor immediately, if you see any changes in breasts like dimpling of the skin, changes in the nipple or presence of any lumps. Avoid consumption of alcohol, driving or travelling, because this medicine may make you feel dizzy and drowsy.

USES OF EMPROGEST 100MG

• Treats amenorrhea (lack of periods)
• Treats abnormal uterine bleeding

HOW EMPROGEST 100MG WORKS

Progesterone binds to and activates the progesterone receptor (PR) present in the stromal cells during the secretory phase of menstrual cycle and during pregnancy. It works by adjusting the hormonal balance within the body, restores progesterone levels in case of deficiency and reduce the symptoms associated with menstrual irregularities.

DIRECTIONS FOR USE

This medicine will be administered to you only by a doctor or a nurse into the muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF EMPROGEST 100MG

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Insomnia:

Try to rest and relax. Take a deep breath. Listen to calm music and rest your mind. Doing meditation might also help.

Skin reactions:

Avoid hot showers because hot water can irritate the scalp. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to a doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking,

• medicines used to treat epilepsy (e.g. phenytoin, phenobarbital, carbamazepine)
• medicines used to treat tuberculosis (e.g. rifampicin, rifabutin)
• medicines used to prevent blood clots (e.g. coumarins, phenindione)
• medicines used to treat fungal infection (e.g. ketoconazole, griseofulvin or terbinafine)
• medicines used to treat diabetes (e.g. insulin, metformin)
• St. John’s Wart (herbal medicine to treat depression)
• bromocriptine (used to treat problems of pituitary gland or Parkinson’s disease)
• ciclosporin (used to suppress immune system)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT EMPROGEST 100MG

Can EMPROGEST 100MG cause fever?

Yes. It may cause fever in some individuals, although not everybody gets them. Consult your doctor before taking any medicine to cure fever.

Can EMPROGEST 100MG cause spotting?

Yes. It may cause spotting or irregular vaginal bleeding in some individuals. Consult your doctor for advice if this bothers you.

Can EMPROGEST 100MG cause weight gain?

Yes. This medicine can cause headache in some individuals. It may be due to water retention and may not be a serious sign. However, consult your doctor if you are bothered by this side effect.

REFERENCES

1. KD. Tripathi. Hormones and related drugs: Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. Seventh edition. 2013. Page – 316-319.

2. Ellis R. Levin and Stephen R. Hammes. Estrogens and Progestins. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1180-1184.

3. Chrousos GP. The Gonadal Hormones & Inhibitors. Basic and Clinical Pharmacology. Fourteenth Edition. New Delhi McGraw Hill Education. 2018. Page – 727- 731

4. Brigham and Women's Hospital. Comparison of Vaginal and Intramuscular Progesterone in Vitrified-warmed Blastocyst Transfer Cycles. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2019] [Accessed 11th November 2020] https://clinicaltrials.gov/ct2/show/NCT02772120

5. Mark Severino, MD. Aurora Fertility Services Organisation, The Women's Center at Aurora BayCare Medical Center. Dysfunctional Uterine Bleeding. The Global Library of Women’s Medicine. [Revised on December 2011] [Accessed 10th November 2020] https://www.glowm.com/section_view/heading/dysfunctional-uterine-bleeding/item/293#6691

6. Watson Laboratories, Inc. U.S. Food & Drug Administration. [Revised on January 2007] [Accessed 11th November 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017362s104lbl.pdf

USEFUL DIAGNOSTIC TESTS

• Anti-Mullerian Hormone
• Glycosylated Hemoglobin
• Testosterone Total
• Thyroid Stimulating Hormone