ELIQUIS 2.5 contains apixaban which belongs to the group of medicines called anticoagulants. A blood clot which blocks an artery (blood vessel) is called an embolism and if the embolism occurs in the arteries of the brain it can cause a stroke. Anticoagulants slow down the time it takes for blood to clot and reduce the risk of embolism.
This medicine is used to reduce the risk of blood clots formation in heart of the patients with atrial fibrillation (an abnormal heartbeat) and other risk factors for stroke. These blood clots might break and travel to the brain, leading to a stroke or to other organs and prevent their normal blood flow (systemic embolism).
ELIQUIS 2.5 can also be used to treat other blood clotting conditions like deep vein thrombosis (blood clots in veins of legs) and pulmonary embolism (blood clot in blood vessels of lungs), and also prevents its recurrence in patients with or without hip or knee replacement operations. This medicine can be taken with or without food.
The most common side effects of taking this medicine are bleeding in eyes, nose, gums, stomach, rectum or vagina. Do not take this medicine, if you have any bleeding disorders. Discuss the risks and benefits with your doctor. Before taking this medicine inform your doctor if you are pregnant, breastfeeding or having any serious kidney or liver disease. This medicine is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking.
ELIQUIS 2.5 selectively inhibits both the free- and clot-bound forms of coagulation factor Xa and the activity of prothrombinase which prevents the conversion of prothrombin into thrombin and thus preventing formation of blood clot.
Take this medicine as directed by your physician. It can be taken with or without food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as whole with a glass of water.
Feeling sick (nausea):
Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.
ELIQUIS 2.5 is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
ELIQUIS 2.5 is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
Do not drive or operate any machines if your ability is affected by this medicine.
Avoid consumption of alcohol while taking this medicine.
ELIQUIS 2.5 should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
Do not take ELIQUIS 2.5 if you have a liver disease which leads to increased risk of bleeding (hepatic coagulopathy). Consult your doctor for advice.
Do not take this medicine if you are allergic (hypersensitive) to apixaban.
ELIQUIS 2.5 should be taken with caution in patients with prosthetic heart valve or other heart disease. Consult your doctor for advice.
Inform your doctor before taking this medicine, if you have
Talk to your doctor, if you are taking,
Drug | : | Apixaban |
Pharmacological Category | : | Anticoagulant |
Therapeutic Indication | : | Blood clots |
Dosage Forms | : | Tablet |
Store below 20-25°C and keep out of reach of children.
Can ELIQUIS 2.5 cause low platelet count?
Yes. This medicine may cause reduced platelet count in blood in some individuals. Consult your doctor for advice.
Should patients stop taking ELIQUIS 2.5 if they are going to have a dental or medical procedure?
This medicine may need to be stopped for one or two days before any planned surgery, dental or medical procedure. Follow the instructions given by the physician. You should not stop taking this medicine without first talking to your doctor or dentist.
When and how do I take this medicine?
Always take this medicine as instructed by your doctor. If you do not take this medicine regularly there is a risk of increase in clot formation.
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2. Gerald G. Briggs, Roger K. Freeman. A. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation, Tenth Edition. 2015. Page - 253-254.
3. James L. Zehnder. Drugs Used in Disorders of Coagulation. Basic & Clinical Pharmacology. Fourteenth Edition. McGraw-Hill Education 2018. Page – 616-617.
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6. Aliaksandr Budovich, Olga Zargarova, and Anna Nogid. Role of Apixaban (Eliquis) in the Treatment And Prevention of Thromboembolic Disease. NCBI; PMC U.S. National Library of Medicine, National Institute of Health. April 2013. [Accessed 27th October 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684191/
7. Catalent Anagni S.R.L., Pfizer Manufacturing Deutschland GmbH, Swords Laboratories T/A Bristol-Myers Squibb Pharmaceutical Operations, External Manufacturing Plaza 254. [Revised on August 2020] [Accessed 27th October 2020] https://www.medicines.org.uk/emc/files/pil.2878.pdf
8. Catalent Anagni S.R.L., Pfizer Manufacturing Deutschland GmbH, Swords Laboratories T/A Bristol-Myers Squibb Pharmaceutical Operations, External Manufacturing Plaza 254. [Revised on August 2020] [Accessed 27th October 2020] https://www.medicines.org.uk/emc/files/pil.4756.pdf
9. Bristol-Myers Squibb Company. [Revised on December 2012] [Accessed 27th October 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202155s000lbl.pdf
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