INTRODUCTION
ELIPRAN 20MG TABLET contains Eletriptan which belongs to the group of medicines called Serotonin receptor agonists. It can be used to treat migraine headache (severe throbbing headache, accompanied by nausea, vomiting and sensitivity to sound and light) with or without aura in adults.
Before the start of a migraine headache, you may experience a phase called an aura, which can involve vision disorder, numbness and speech disorders.
ELIPRAN 20MG TABLET is not recommended for use in patients with severe liver and kidney disease, high blood pressure, heart problems and stroke. ELIPRAN 20MG TABLET should be used with caution in patients with mild or moderate liver, kidney disease and diabetes. Contact your doctor before taking it.
ELIPRAN 20MG TABLET should be used during pregnancy only if clearly necessary. It is recommended to avoid breast-feeding for 24 hours after taking this medicine.
ELIPRAN 20MG TABLET is not recommended for use in children and adolescents under 18 years of age and in elderly patients over 65 years of age. Consult your doctor before taking this medicine.
The most common side effects of taking ELIPRAN 20MG TABLET are heart palpitation, increased heart rate, dizziness, spinning sensation (vertigo), headache, feeling sleepy etc. Contact your doctor if any of the symptoms worsen.
USES OF ELIPRAN 20MG TABLET
To treat:
- migraine headache with or without aura
HOW ELIPRAN 20MG TABLET WORKS
ELIPRAN 20MG TABLET works by narrowing blood vessels in the brain, stopping pain signal from being sent to the brain and blocking the release of certain natural substances that cause pain, nausea and other symptom of migraine.
DIRECTIONS FOR USE
Take ELIPRAN 20MG TABLET as advised by your physician. It can be used before or after food and drinks. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF ELIPRAN 20MG TABLET
COMMON
- heart palpitation, increased heart rate
- dizziness, sensation of spinning (vertigo), headache, feeling sleepy, reduced sense of touch or pains
- sore throat, throat tightness, dry mouth
- abdominal pain, indigestion (upset stomach), nausea and vomiting
- stiffness (increased muscle tone), muscle weakness, back pain, muscle pain
- generally feeling weak, tiredness, feeling hot, chills, runny nose, sweating, tingling or abnormal sensation, flushing, pain
UNCOMMON
- difficulty breathing, yawning
- swelling of the face or hand and feet, inflammation or infection of the tongue, skin rash, itching
- increased sense of touch or pain (hyperaesthesia), loss of co-ordination, slow or reduced movements, tremor, slurred speech
- not feeling oneself (depersonalisation), depression, thinking strangely, feeling agitated, feeling confused, mood swings (euphoria), period of unresponsiveness (stupor), general feeling of discomfort, illness or lack of wellbeing (malaise), sleeplessness (insomnia)
- loss of appetite and weight loss (anorexia), taste disturbance, thirst
- degeneration of the joint (arthrosis), bone pain, joint pain
- increased need to pass water (urinate), problem with urinating, passing excessive quantity of urine, diarrhoea
- abnormal vision, eye pain, intolerance to light, dry or watery eye
- ear pain, ringing in the ear (tinnitus)
- poor circulation (Peripheral vascular disorder)
RARE
- shock, asthma, hive (urticaria), skin disorder, swollen tongue
- throat or chest infection, swollen lymph gland
- slow heart rate
- emotionally fragile (mood swings)
- muscle disorder, twitching
- constipation, inflamed gullet, belching
- breast pain, heavy or prolonged menstrual period
- eye infection (conjunctivitis)
- changes to voice
Stop taking ELIPRAN 20MG TABLET and contact your physician immediately if you experience any of the following side effects:
- allergic reaction symptoms such as sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips, rash or itching (especially affecting the whole body)
- symptoms of problems of the blood circulation of the heart (Ischemic heart disease) include chest pain and tightness, which may be intense and involve the throat
- signs and symptoms of serotonin syndrome which may include restlessness, hallucinations, loss of co-ordination, fast heartbeat, increase body temperature, fast changes in blood pressure and overactive reflexes
HOW TO MANAGE SIDE EFFECTS
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your doctor if the dry mouth gets worse.
Headache:
Rest and relax. Drink plenty of fluids such as water or ORS (Oral Rehydrating Solution) and apply a pain-relieving balm on the head if necessary. Contact your doctor if your headache did not improve.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Contact your doctor if your dizziness did not improve.
Nausea and vomiting:
Take ELIPRAN 20MG TABLET, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting did not improve.
Stomach pain:
Try to have smaller meals but take frequently. Keep a heat pad on your stomach. Do not self-treat and contact your doctor if the stomach pain did not improve.
Skin rash:
Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.
Indigestion:
Eat smaller and frequent meals. Eat and drink slowly and exercise regularly. If the indigestion does not improve, contact your doctor.
Loss of appetite:
Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you're hungry. Eat a nutritious snack which is rich in calories and protein, such as dried fruit and nuts. Contact your doctor if your appetite did not improve.
WARNING & PRECAUTIONS
PREGNANCY
ELIPRAN 20MG TABLET should be used during pregnancy only if clearly necessary. Contact your doctor before taking ELIPRAN 20MG TABLET.
BREASTFEEDING
ELIPRAN 20MG TABLET may pass through the breast milk and it is recommended to avoid breast-feeding for 24 hours after taking ELIPRAN 20MG TABLET.
DRIVING AND USING MACHINES
ELIPRAN 20MG TABLET or the migraine itself may make you sleepy. This medicine may also make you feel dizzy. Therefore, avoid driving and using machines during the migraine attack or after taking ELIPRAN 20MG TABLET.
KIDNEY
ELIPRAN 20MG TABLET is not recommended in patients with severe kidney disease. It should be used with caution in patients with mild or moderate kidney disease and may require dose adjustment. Contact your doctor before taking ELIPRAN 20MG TABLET.
LIVER
ELIPRAN 20MG TABLET is not recommended in patients with severe liver disease. It should be used with caution in patients with mild or moderate liver disease Contact your doctor before taking ELIPRAN 20MG TABLET.
ALLERGY
Do not take ELIPRAN 20MG TABLET if you are allergic to eletriptan or any of the other ingredients of this medicine.
HEART DISEASE
ELIPRAN 20MG TABLET is not recommended for use in patients with moderate to severe high blood pressure or untreated mild high blood pressure, heart problems such as heart attack, angina (chest pain), heart failure or significant abnormal heart rhythm (arrhythmia), temporary, sudden narrowing of one of the coronary arteries. Contact your doctor before taking ELIPRAN 20MG TABLET.
Inform your doctor before taking this medicine if you or anybody in your family have coronary artery disease or if you have ever been told that you may have an increased risk of heart disease.
OTHERS
ELIPRAN 20MG TABLET is not recommended for use if you:
- have poor circulation (peripheral vascular disease)
- have ever had a stroke (even a mild one that lasted for only a few minutes or hours)
Before taking ELIPRAN 20MG TABLET, inform your doctor if you:
- have diabetes
- have smoking habit or use nicotine replacement therapy
- have intolerance to sugars
Use in pediatrics:
ELIPRAN 20MG TABLET is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking ELIPRAN 20MG TABLET.
Use in geriatrics:
ELIPRAN 20MG TABLET is not recommended for use in elderly patients over 65 years of age. Consult your doctor before taking ELIPRAN 20MG TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking ELIPRAN 20MG TABLET inform your doctor if you are taking any of the following medicine:
- medicines used to treat or prevent migraine (Ex. Ergotamine, methylsergide, sumatriptan, rizatriptan, naratriptan, zolmitriptan, almotriptan and frovatriptan)
- ketoconazole and itraconazole (used to treat fungal infections)
- erythromycin, clarithromycin, josamycin, troleandomycin (used to treat bacterial infections)
- ritonavir, indinavir and nelfinavir (used to treat AIDS and HIV)
- herbal medicine used to treat depression Ex. St. John’s wort (Hypericum perforatum)
- medicines used to treat depression and anxiety (Ex. citalopram, escitalopram, fluoxetine, duloxetine, venlafaxine)
Overdosage:
If you or anyone else accidentally take too much of ELIPRAN 20MG TABLET, contact your doctor immediately or visit the nearby hospital. Symptoms of overdose includes high blood pressure and heart problems.
SYNOPSIS
| Drug | : | Eletriptan |
| Pharmacological Category | : | Serotonin Receptor Agonist |
| Therapeutic Indication | : | Migraine headache with or without aura |
| Dosage Forms | : | Tablet, Combi Kit |
MORE INFORMATION
- Keep ELIPRAN 20MG TABLET out of reach of children
- Store ELIPRAN 20MG TABLET below 30°C
FAQs ABOUT ELIPRAN 20MG TABLET
Q: Can I use ELIPRAN 20MG TABLET daily?
A: Take ELIPRAN 20MG TABLET as advised by your doctor. If you repeatedly use ELIPRAN 20MG TABLET or any medicines for the treatment of migraine over several days or weeks, this can cause daily long-term headaches. Tell your doctor if you experience this as you might need to stop treatment for a while.
Q: When is the best time to take ELIPRAN 20MG TABLET?
A: Take ELIPRAN 20MG TABLET as advised by your doctor. It can be taken at any time after the start of the migraine headache, but it is best to take it as soon as possible. However you should only take ELIPRAN 20MG TABLET during the headache phase of the migraine. Contact your doctor for advice before taking ELIPRAN 20MG TABLET.
Q: How long does it takes ELIPRAN 20MG TABLET to work?
A: ELIPRAN 20MG TABLET generally begins to work within 30 minutes to 2 hours. It is intended to reduce acute symptoms of migraine attacks that have already begun. ELIPRAN 20MG TABLET should not be used as a prophylactic therapy to prevent the onset of migraine. Contact your doctor if your symptoms did not improve.
Q: Can I use ELIPRAN 20MG TABLET to prevent migraine?
A: No, You should not take this medicine to prevent a migraine attack as this medicine should be taken only after the attack of migraine. Contact your doctor for prevention of migraine.
Q: Can I take two doses of ELIPRAN 20MG TABLET to relieve migraine faster?
A: No. If the first tablet does not relieve your migraine, do not take a second tablet for the same attack. If after a first tablet your migraine is relieved and then comes back, you may take a second tablet. However, after taking the first tablet you must wait at least 2 hours before taking the second tablet. You should not take more than the recommended dose advised by your doctor. If you find that your dose of ELIPRAN 20MG TABLET does not relieve your migraines, tell your doctor – he or she may decide to increase the dose for future attacks.
REFERENCES
1. Sean C Sweetman. Antimigraine Drugs. Martindale The Complete Drug Reference. 36th edition. 2009. Page – 619 to 620.
2. Smith LA, Oldman AD, McQuay HJ, Moore RA. WITHDRAWN: Eletriptan for acute migraine. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. July 2001. [Accessed on 8th November 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564092/
3. Capi M, Curto M, Lionetto L, de Andes F, Gentile G, Negro A, Martelletti P. Eletriptan in the management of acute migraine: an update on the evidence for efficacy, safety and consistent response. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. September 2016. [Accessed on 8th November 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994780/
4. Upjohn UK Limited. Electronic Medicines Compendium (EMC). [Revised in July 2020] [Accessed on 8th November 2021] https://www.medicines.org.uk/emc/files/pil.1265.pdf https://www.medicines.org.uk/emc/product/1265/smpc
5. Bethesda (MD). Eletriptan. National Institute of Health: National Library of Medicine. Medline Plus. March 2016. [Accessed on 8th November 2021] https://medlineplus.gov/druginfo/meds/a603029.html
USEFUL DIAGNOSTIC TESTS
- Complete blood count
- Liver function test
PRODUCT DETAILS
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