Dyamide Plus 50/20mg Tablet 10'S

Hypertension Rx required
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Best Price*  ₹ 50.79
MRP ₹63.49
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Macleods Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

DYAMIDE PLUS is a fixed-dose combination of Spironolactone and Torsemide which belongs to the group of medicines called Diuretics. It is used to treat edema (fluid accumulation) in the body that is associated with secondary hyperaldosteronism (excessive secretion of aldosterone due to kidney problems), liver cirrhosis (inflammation of the liver), congestive heart failure, nephrotic syndrome (a kidney disorder which excretes more protein in urine) or resistant hypertension (high blood pressure that cannot be controlled by medicines).

Spironolactone is a potassium sparing diuretic and torsemide is a loop diuretic. They act by removing the excess water and certain electrolytes (sodium and chloride) from the body in the form of urine. Unlike other diuretics, DYAMIDE PLUS retains potassium in the body which prevents the risk of developing hypokalaemia (low blood potassium levels).

Before taking DYAMIDE PLUS inform your doctor if you have any liver, kidney, or heart problems. Avoid consumption of alcohol while taking DYAMIDE PLUS as it may make you feel dizzy or faint even while changing posture.

Avoid consuming potassium rich diet or potassium supplements while taking DYAMIDE PLUS, as it may further increase the levels of potassium in your body. DYAMIDE PLUS is not recommended for use in pregnant or breastfeeding women due to increased risk of side effects.

DYAMIDE PLUS may alters the levels of electrolytes in your body and may make you feel dizzy or tired very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and increase or decrease the dose of this medicine accordingly.

The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, increased urination, or impotence. Consult your doctor if any of the side effect bothers you.

USES OF DYAMIDE PLUS

  • Treat edema (fluid retention) associated with secondary hyperaldosteronism, liver cirrhosis, congestive heart failure, nephrotic syndrome, or resistant hypertension

HOW DYAMIDE PLUS WORKS

DYAMIDE PLUS acts by removing the excess water and certain electrolytes (sodium and chloride) from the body in the form of urine while simultaneously maintaining the levels of potassium levels.

DIRECTIONS FOR USE

Take DYAMIDE PLUS as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking DYAMIDE PLUS unless your doctor tells you to stop.

SIDE EFFECTS OF DYAMIDE PLUS

COMMON

  • headache, dizziness
  • nausea, vomiting
  • general weakness
  • increased urination
  • excessive thirst
  • impotence
  • indigestion

RARE

Stop taking DYAMIDE PLUS and contact your doctor immediately if you experience any of the following side effects:

  • irregular heartbeat, chest pain
  • bleeding from the gut or diarrhoea
  • hyperglycaemia (increased blood glucose levels causing excessive urination and thirst, fatigue, headache)
  • hyperuricemia (increased uric acid levels in blood causing joint pain, redness, swelling and of joints)
  • hypokalaemia (low blood potassium levels causing constipation, tiredness, muscle weakness, tingling and numbness)
  • hypotension (low blood pressure causing fainting, tiredness, blurred vision, nausea)
  • hypovolemia (loss of body fluids causing headache, dizziness, low blood pressure, weakness, drowsiness, confusion, loss of appetite and cramps)
  • blood clot formation in the body
  • skin rash
  • rectal bleeding
  • feeling faint

VERY RARE

NA

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take DYAMIDE PLUS with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely if you feel dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

PREGNANCY

DYAMIDE PLUS is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.

BREASTFEEDING

DYAMIDE PLUS is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or handle any heavy tools or machines if you experience dizziness, drowsiness, or blurred vision after taking DYAMIDE PLUS.

ALCOHOL

Avoid consumption of alcohol while taking DYAMIDE PLUS as it might make you feel dizzy or faint even when you change posture.

KIDNEY

DYAMIDE PLUS is not recommended for use in patients with moderate to severe kidney diseases (such as difficulty in passing urine or acute renal failure). Therefore, consult your doctor before taking it.

LIVER

DYAMIDE PLUS is not recommended for use in patients liver diseases. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take DYAMIDE PLUS if you are allergic to Torsemide, Spironolactone or sulfonylureas (Ex. glimepiride, glipizide).

HEART DISEASE

DYAMIDE PLUS is not recommended for use in patients with heart diseases (such as low blood pressure or abnormal heart rate). Therefore, consult your doctor before taking it.

OTHERS

DYAMIDE PLUS is not recommended for use if you:

  • have high levels of potassium in your blood (hyperkalaemia)
  • have Addison’s disease (deficiency of cortisol and aldosterone)

Use in pediatrics:

There is no proper information regarding the use of DYAMIDE PLUS in children and adolescents (below 18 years). Therefore, consult your doctor before taking it.

Use in geriatrics:

DYAMIDE PLUS should be used with caution in elderly patients. Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interaction:

Before taking DYAMIDE PLUS, inform your doctor if you are taking any of the following:

  • cholestyramine (a medicine used to control blood cholesterol levels)
  • medicines that exert effects on heart function during emergency conditions (Ex. adrenaline, noradrenaline)
  • probenecid (a medicine used to treat gout)
  • lithium (a medicine used to treat mental illness)
  • medicines used to reduce anxiety and to induce sleep (Ex. phenobarbital) 
  • corticosteroids (used to treat inflammation) Ex. methylprednisolone
  • adrenocorticotropic hormone (used to treat cortisol deficiency)
  • medicines used to relax muscles (Ex. tubocurarine)
  • medicines used for pain relief (Ex. indomethacin, aspirin, morphine, fentanyl, codeine)
  • cardiac glycosides (used to treat cardiac failure) Ex. digoxin
  • carbenoxolone (a medicine used to treat ulcers)
  • medicines used to treat bacterial infections Ex. trimethoprim, sulfamethoxazole, ceftriaxone, cefazolin, gentamycin, streptomycin
  • cotrimoxazole (a medicine used to treat fungal infections)
  • cisplatin (used to treat cancer)
  • other potassium-sparing diuretics (used to treat fluid accumulation) Ex. eplerenone, aldactone
  • heparin and low molecular weight heparin (used to prevent blood clots)
  • potassium supplements (used to treat potassium deficiency) Ex. potassium chloride
  • medicines used to treat high blood pressure such as ACE inhibitors, angiotensin II blockers or beta-blockers (Ex. enalapril, telmisartan, valsartan, propranolol)
  • medicines used to treat diabetes (Ex. metformin, glimepiride)

B. Drug-Food Interaction:

Avoid foods rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes such as potassium chloride.

Overdosage:

If you or anyone else accidentally took more DYAMIDE PLUS, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include dehydration, low blood pressure, decreased body fluids and electrolytes levels, low blood sodium levels, abnormal blood potassium levels, increased RBC count, drowsiness, mental confusion, erythematous rash, nausea, vomiting, dizziness, diarrhoea, or liver problems.

SYNOPSIS

Drug :   Spironolactone, Torsemide
Pharmacological Category :  

Potassium sparing diuretics, Loop diuretics

Therapeutic Indication :  

Fluid Retention

Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep DYAMIDE PLUS out of reach of children
  • Store DYAMIDE PLUS at room temperature

FAQs ABOUT DYAMIDE PLUS

What is the use of DYAMIDE PLUS?

DYAMIDE PLUS is a prescription medicine used to treat edema associated with various heart, liver, or kidney problems. It removes excess water accumulated in the body via urine.

Can I take DYAMIDE PLUS daily?

Take DYAMIDE PLUS as advised by your physician. Your doctor will evaluate your health condition and suggests you the number of doses that needs to be taken per day.

What are the possible side effects of DYAMIDE PLUS?

The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, and increased urination. It may also cause impotence in men. Consult your doctor if any of the side effect bothers you. Also inform your doctor immediately if you experience irregular heartbeat, joint pain, muscle pain, extreme dizziness or fainting or rectal bleeding after taking DYAMIDE PLUS.

What is the best time to take DYAMIDE PLUS?

It is advisable to take DYAMIDE PLUS in the morning preferably after meals. This may avoid frequent urination at the night. However, consult your doctor regarding the time of administration of DYAMIDE PLUS.

How long does it take for DYAMIDE PLUS to show the results?

It may take a few weeks for DYAMIDE PLUS to show the results, and so take DYAMIDE PLUS regularly as advised by your physician to see the optimum results.

Can DYAMIDE PLUS cause dizziness?

Yes, DYAMIDE PLUS may cause dizziness due to the loss of fluids from the body. To avoid this, keep yourself hydrated by drinking plenty of fluids. Avoid driving or operating any tools or machines if you feel dizzy. Consult your doctor if you experience extreme dizziness.

Can I consume alcohol while taking DYAMIDE PLUS?

Avoid consumption of alcohol while taking DYAMIDE PLUS as it might make you feel dizzy or faint even when you change posture.

Do I have any food restrictions while taking DYAMIDE PLUS?

Avoid food rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes containing potassium while taking DYAMIDE PLUS. It is because DYAMIDE PLUS can reabsorb potassium in the kidneys, and so additionally consumption of potassium rich foods or supplements may further increase the levels of potassium in the blood.

Do we need any laboratory investigations while taking DYAMIDE PLUS?

Yes. DYAMIDE PLUS may alter the electrolyte balance in your body, and make you feel tired or dehydrated very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and increase or decrease the dose of this medicine accordingly.

Can DYAMIDE PLUS reduce my weight?

DYAMIDE PLUS does not have any impact on reducing your weight. But, due to removal of excess water from the body, you may experience a slight reduction in body weight.

Can I take DYAMIDE PLUS to reduce my postpartum belly?

No. DYAMIDE PLUS is not indicated for use in postpartum women. Do not take DYAMIDE PLUS unless your doctor has prescribed it. It is not advisable to breastfeed while taking DYAMIDE PLUS. Consult your doctor before taking DYAMIDE PLUS.

Can DYAMIDE PLUS cause cancer?

No. Research does not suggest any risk of cancer while taking [GBNEYWORD]. If you are doubtful consult your doctor for advice.

 Can I take DYAMIDE PLUS on my own?

No. DYAMIDE PLUS is a prescription medicine. It should be used only when prescribed by a physician. Do not take DYAMIDE PLUS on your own without consulting your doctor.

Can DYAMIDE PLUS affect sense of hearing?

Yes, some rare cases of hearing loss have been reported with the use of DYAMIDE PLUS. This condition is often reversible after discontinuing therapy with DYAMIDE PLUS. Consult your doctor immediately if you experience any disturbances in the sense of hearing.

Can the use of DYAMIDE PLUS cause frequent urination?

Yes. DYAMIDE PLUS may cause frequent urination. It tends to excrete the accumulated fluid from the body in the form of urine. As a result, you may experience an increase in tendency to urinate. If this bothers you, contact your doctor.

Can the use of [GNKEYWORD] make me more tired?

Yes. DYAMIDE PLUS may make you feel tired easily because it removes the excess fluids from the body. This reduces your energy levels and make you feel very tired. To avoid this, keep yourself hydrated by drinking plenty of fluids. If you experience extreme tiredness that hinders your daily activities, consult your doctor for advice.

REFERENCES

1. K.D. Tripathi. Diuretics Essentials of pharmacology seventh edition, 2013 Page no – 581 and 587.

2. Juan Tamargo 1, Julian Segura, Luis M Ruilope. Diuretics in the treatment of hypertension. Part 2: loop diuretics and potassium-sparing agents. NIH. National Library of Medicine. National Centre for biotechnology information. Pubmed.gov. April 2014. [Accessed on 17th May 2022] https://pubmed.ncbi.nlm.nih.gov/24456327/

3. Cipla Ltd. Spironolactone/torsemide. Ciplamed.com. [Revised in April 2015]. [Accessed on 17th May 2022] https://www.ciplamed.com/content/dytor-plus-tablets

4. TORRENT PHARMACEUTICALS LTD. Spironolactone/torsemide [Revised in July 2016]. [Accessed on 17th May 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1818.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    SPIRONOLACTONE 50MG+Torasemide(Torsemide) 20 MG
    Hsn Code
    30049079
ALTERNATE BRANDS
Torget Plus 20mg Tablet 10'S
Prescription Hypertension Rx required
Rs.162.14
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