DUZELA 20mg Capsule 10's

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Drug Information

What is Duloxetine Hydrochloride used for?

Duloxetine Hydrochloride capsule/tablet is used for the treatment of the following:

  • Depression
  • Anxiety disorders
  • Symptoms of peripheral neuropathy in diabetic patients
  • Fibromyalgia
  • Chronic back pain

Duloxetine Hydrochloride may also be prescribed for other conditions as determined by the doctor.

How does Duloxetine Hydrochloride work?

Duloxetine Hydrochloride belongs to the class of drugs called selective serotonin and norepinephrine reuptake inhibitor (SNRI). The drug acts by stabilizing the action of certain chemicals in the CNS that cause depression and anxiety. Thus, it inhibits the pain signals from reaching the brain and controls the actions associated with serotonergic and noradrenergic activity in the central nervous system.

How to take Duloxetine Hydrochloride?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Duloxetine Hydrochloride capsule/tablet as prescribed by your doctor.

  • Swallow the tablet/capsule Do not crush or chew the tablet/capsule. Do not tear open the capsule. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Duloxetine Hydrochloride, please take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of Duloxetine Hydrochloride include the following:

  • Severe drowsiness
  • Fainting
  • Trouble breathing
  • Agitation
  • Lack of coordination
  • Restlessness
  • Shivering
  • Trembling
  • Loss of bladder control

You must seek immediate medical care if you experience any of the above symptoms.

What are the drugs that interact with Duloxetine Hydrochloride?

Drugs that interact with Duloxetine Hydrochloride include the following:

  • Acetaminophen
  • Aspirin
  • Chlorpheniramine
  • Ciprofloxacin
  • Ergotamine
  • Fluoxetine
  • Imipramine
  • Methenamine
  • Naltrexone
  • Pentazocine
  • Salicylamide
  • Tramadol
  • Zolmitriptan

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Duloxetine Hydrochloride?

The following are the most common side effects of Duloxetine Hydrochloride:

  • Nausea
  • Loss of appetite
  • Dry mouth
  • Tiredness
  • Increased sweating
  • Fatigue
  • Constipation
  • Drowsiness

The following are the severe side effects and you may require immediate medical attention:

  • Upper abdominal pain
  • Hallucinations
  • Muscle twitching
  • Profuse sweating
  • Lack of coordination
  • Tremors
  • Seizures
  • Changes in blood pressure

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Duloxetine Hydrochloride?

  • Avoid using the medicine if you are allergic to Duloxetine Hydrochloride or similar drugs.
  • Seek doctor’s advice before taking any other drug or herbal products while on Duloxetine Hydrochloride.
  • Do not stop using the medication abruptly unless instructed by the doctor. Discontinuing the medication suddenly may cause the illness to return.
  • Avoid consumption of alcohol as it may alter the absorption of Duloxetine Hydrochloride .
  • Do not drive or operate heavy machinery if Duloxetine Hydrochloride causes dizziness or blurred vision.
  • Be cautious while taking Duloxetine Hydrochloride in geriatric patients as they are more sensitive to the risk of side effects.

You are advised not to take Duloxetine Hydrochloride if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Duloxetine Hydrochloride?

  • Tell your doctor if you have any history of drug addiction or suicidal thoughts.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Tell your doctor if you have any history of severe kidney or liver diseases.
  • Inform your doctor before taking Duloxetine Hydrochloride during breastfeeding because the safe use of the drug is not yet established.

Frequently Asked Questions about Duloxetine Hydrochloride

  1. What are the contraindications of Duloxetine Hydrochloride?
  2. Avoid Duloxetine Hydrochloride medicine if you are using MAO indicators. Please consult your doctor before taking Duloxetine Hydrochloride.

  3. Is it safe to take Duloxetine Hydrochloride while suffering from Parkinson’s disease?
  4. Inform your doctor before taking Duloxetine Hydrochloride medication while suffering from Parkinson’s disease.

  5. Is it safe to alter the dose of Duloxetine Hydrochloride?
  6. No. Altering the dose of Duloxetine Hydrochloride is not advisable as it can increase the risk of side effects.

  7. Do I need to be monitored for any laboratory parameters while taking Duloxetine Hydrochloride?
  8. Diabetic patients need to monitor their blood glucose levels as Duloxetine Hydrochloride can affect the sugar levels in the body.

  9. Is it safe to take Duloxetine Hydrochloride during pregnancy?
  10. Consult your doctor before taking Duloxetine Hydrochloride medication during pregnancy as it can cause harm to the unborn baby.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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