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Drug Information

What is Formoterol Fumarate + Tiotropium Bromide combination used for?

Formoterol Fumarate + Tiotropium Bromide combination is used for the treatment of chronic obstructive pulmonary disease (COPD). This combination reduces the severity of following signs and symptoms in patients with COPD:

  • Tightness in the chest
  • Wheezing
  • Shortness of breath
  • Chronic cough with sputum

Formoterol Fumarate + Tiotropium Bromide may also be prescribed for other conditions as determined by the doctor.

How does Formoterol Fumarate + Tiotropium Bromide combination work?

Formoterol Fumarate + Tiotropium Bromide is a combination of long-acting beta-agonist and anticholinergic agent respectively. Formoterol fumarate inhibits the release of inflammatory mediators such as histamines and leukotrienes, and helps in the relaxation of bronchial muscles.

Tiotropium Bromide acts on certain receptors in the bronchioles of the lung and prevents the spasm of the airway wall. Thus, Formoterol Fumarate + Tiotropium Bromide combination relieves the symptoms of COPD by bronchodilation and aids in easier breathing.

How to use Formoterol Fumarate + Tiotropium Bromide combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual.

Formoterol Fumarate + Tiotropium Bromide combination should be inhaled by mouth using an inhaler and should never be swallowed directly. Before using it, shake the inhaler for at least 10 seconds.

If you miss a dose of Formoterol Fumarate + Tiotropium Bromide combination, please use it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

The overdose symptoms of Formoterol Fumarate + Tiotropium Bromide combination may include:

  • Muscle pain
  • Seizures
  • Shortness of breath

What are the drugs that interact with Formoterol Fumarate + Tiotropium Bromide combination?

Drugs that interact with Formoterol Fumarate + Tiotropium Bromide combination  include the following:

  • Atropine
  • Atenolol
  • Furosemide
  • Hydrochlorothiazide
  • Phenelzine
  • Potassium chloride
  • Pramlintide
  • Prednisone
  • Propranolol
  • Salmeterol
  • Secretin
  • Theophylline
  • Trimethobenzamide
  • Triprolidine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Formoterol Fumarate + Tiotropium Bromide combination?

The following are the most common side effects of Formoterol Fumarate + Tiotropium Bromide combination:

  • Cough
  • Constipation
  • Dry mouth and throat
  • Dizziness
  • Stomach upset
  • Stuffy nose

The following are the severe side effects and you may require immediate medical attention:

  • Blurred vision
  • Bronchitis
  • Rash
  • Rapid heartbeat (tachycardia)
  • Nausea
  • Sinusitis
  • Chest pain
  • Tremors

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions Formoterol Fumarate + Tiotropium Bromide combination?

  • Avoid using the medicine if you are allergic to Formoterol Fumarate + Tiotropium Bromide combination or similar drugs.
  • Seek doctor’s advice before taking any other drug or herbal products while on Formoterol Fumarate + Tiotropium Bromide combination.
  • Avoid Formoterol Fumarate + Tiotropium Bromide combination during pregnancy or breastfeeding because the safe use of the drug is not yet established.

You are advised not to use Formoterol Fumarate + Tiotropium Bromide combinationif:

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Formoterol Fumarate + Tiotropium Bromide combination?

  • Tell your doctor if you have any history of kidney problem, glaucoma, urinary problems, heart disease, high blood pressure, or congestive heart failure, epilepsy, diabetes, overactive thyroid or irregular heartbeat.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.

Frequently asked questions about Formoterol Fumarate + Tiotropium Bromide combination

:

  1. I am on Formoterol Fumarate + Tiotropium Bromide combination for chronic obstructive pulmonary disease. Can I stop the drug if I feel better?
  2. No, you should not discontinue Formoterol Fumarate + Tiotropium Bromide combination without consulting your doctor.

  3. How should Formoterol Fumarate + Tiotropium Bromide combination be stored?
  4. Store the drug below 25°C in a cool and dry place. Avoid exposure to direct sunlight.

  5. Can I take other medications while on Formoterol Fumarate + Tiotropium Bromide combination?
  6. It is important to consult your doctor before taking any other drug with Formoterol Fumarate + Tiotropium Bromide combination, because certain combination of drugs may cause serious side effects that worsen the condition.

  7. What are the other formulations available for Formoterol Fumarate + Tiotropium Bromide combination?
  8. Formoterol Fumarate + Tiotropium Bromide combination is available only in the form of an inhaler.

  9. How long should I take Formoterol Fumarate + Tiotropium Bromide combination?
  10. You must use the inhaler as recommended by the doctor. Do not discontinue the drug until advised by the doctor.

Disclaimer:

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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