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INTRODUCTION

DOXOMONT TABLET is a combination of Doxofylline and Montelukast which belongs to the group of medicines called Bronchodilators and Leukotriene Receptor Antagonists respectively. It is used to treat asthma and chronic obstructive pulmonary disease (COPD).

It can also be used to reduce airway inflammation (such as bronchitis), apnea (lack of breathing), seasonal allergic rhinitis (nasal congestion, repeated sneezing, nasal itching or a red, watery and itchy eyes) and other respiratory diseases associated with bronchospasm (tightening of airways).

Before taking DOXOMONT TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have hypertension, hyperthyroidism, stomach ulcers or any concomitant infections as a precaution.

DOXOMONT TABLET is not recommended for use in patients with severe hypotension or heart problems (such as myocardial infarction). It is also not suitable for use in breastfeeding women.

Inform your doctor before taking DOXOMONT TABLET if you are pregnant or planning to become pregnant. The most common side effects of taking DOXOMONT TABLET are nausea, vomiting, upper stomach pain, headache, irritability, upper respiratory tract infections, lack of sleep, skin rash and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.

USES OF DOXOMONT TABLET

It is used to treat and prevent:

  • Asthma & COPD
  • Bronchitis (inflammation of the airways)
  • Apnea (breathing stops for a brief period)
  • Seasonal allergic rhinitis (nasal congestion, repeated sneezing, nasal itching or a red, watery and itchy eyes)
  • Exercise induced bronchospasm (narrowing of airways)

HOW DOXOMONT TABLET WORKS

DOXOMONT TABLET is a bronchodilator with anti-inflammatory properties. It blocks the release of certain chemicals (such as phosphodiesterase, leukotrienes) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways and reduces airway inflammation. This allows the air to pass through more freely through the airways which makes breathing easier.

DIRECTIONS FOR USE

Take DOXOMONT TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose, duration of therapy and number of doses per day depending upon your age, body weight and disease condition.

Do not stop taking DOXOMONT TABLET once your symptoms subside without consulting your doctor.

SIDE EFFECTS OF DOXOMONT TABLET

COMMON

  • nausea, vomiting
  • upper stomach pain
  • headache
  • irritability
  • lack of sleep (insomnia)
  • abnormal or rapid heartbeat
  • fast breathing
  • upper respiratory tract infection
  • diarrhoea
  • skin rash or itching
  • fever
  • increased liver enzymes

UNCOMMON

  • nosebleed
  • dry mouth, indigestion
  • bruising
  • joint pain, muscle cramps
  • bedwetting in children
  • weakness, tiredness, feeling unwell
  • dizziness, drowsiness
  • oedema

RARE

  • hyperglycemia (high blood sugar levels)
  • albuminuria (presence of albumin in urine)

Stop taking DOXOMONT TABLET and consult your doctor immediately if you experience any of the following side effects:

  • allergic reactions (swelling of the face, lips, tongue and/or throat which may cause difficulty in breathing or swallowing)
  • behaviour and mood related changes (anxiety, aggressive behaviour or hostility, depression, suicidal thoughts, hallucinations)
  • increased bleeding tendency
  • feeling shaky (tremor)
  • strong, fast or irregular heartbeats
  • flu-like symptoms accompanied with pins and needles, numbness of arms or legs, worsening of pulmonary symptoms and/or rash
  • cardiac arrhythmias
  • fits (tonic-clonic seizures)

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take DOXOMONT TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

PREGNANCY

DOXOMONT TABLET should be used in pregnant women only if it is considered necessary by the physician. Your doctor will prescribe you with DOXOMONT TABLET after evaluating the risks and benefits of the therapy.

BREASTFEEDING

DOXOMONT TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

DOXOMONT TABLET does not affect your ability to drive or operate machines. However, do not drive or handle any heavy tools or machines if your ability is affected by DOXOMONT TABLET.

KIDNEY

DOXOMONT TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

LIVER

DOXOMONT TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Talk to your doctor before taking DOXOMONT TABLET if you are allergic to Montelukast, Doxofylline or to any other similar medicines (such as etophylline, aminophylline).

HEART DISEASE

DOXOMONT TABLET is not recommended for use in patients with heart problems (such as heart attack or myocardial infarction). It should be used with caution in patients with congestive heart failure. Therefore, consult your doctor before taking it.

OTHERS

DOXOMONT TABLET is not recommended for use if you:

  • have severe hypotension (low blood pressure)
  • have an asthma attack

Before taking DOXOMONT TABLET tell your doctor if you:

  • have concomitant infections
  • have hypertension (high blood pressure)
  • have severe hypoxemia (low oxygen levels in blood)
  • have hyperthyroidism
  • have chronic cor pulmonale (right side of the heart fails to function properly)
  • have peptic ulcer

Use in Pediatrics:

There is no adequate information regarding the use of DOXOMONT TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

Use in Geriatrics:

DOXOMONT TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking DOXOMONT TABLET, inform your doctor if you are taking any of the following medicines such as:

  • other methylxanthines (used to treat respiratory problems) Ex. etophylline, aminophylline
  • medicines used to treat bacterial infections (such as erythromycin, troleandomycin, lincomycin, clindamycin)
  • allopurinol (a medicine used to treat gout)
  • cimetidine (a medicine used to treat stomach ulcers)
  • influenza vaccine
  • propranolol (a medicine used to treat heart problems)
  • phenytoin (a medicine used to treat fits)
  • sympathomimetic drugs (medicines used to increase heart rate and hypertension) Ex. ephedrine
  • medicines used to treat fits (Ex. phenobarbital, phenytoin)
  • rifampicin (a medicine used to treat tuberculosis)
  • medicines used to relieve fever, pain and inflammation (Ex. aspirin, ibuprofen)
  • gemfibrozil (a medicine used to control blood cholesterol levels)

B. Drug-Food Interactions:

Limit the consumption of foods and beverages rich in caffeine (such as coffee) while taking DOXOMONT TABLET.

Overdosage:

If you or anyone else accidentally took more DOXOMONT TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include stomach pain, sleepiness, thirst, headache, vomiting and hyperactivity.

SYNOPSIS

Drug :   Doxofylline, Montelukast
Pharmacological Category :   Methylxanthines, Leukotriene receptor antagonists
Therapeutic Indication :   Bronchial Asthma, Chronic Obstructive Pulmonary Disease, Apnea, Allergic rhinitis, Bronchospasm
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep DOXOMONT TABLET out of reach of children
  • Store DOXOMONT TABLET at room temperature

FAQs ABOUT DOXOMONT TABLET

Q: How DOXOMONT TABLET works?

A: DOXOMONT TABLET is a bronchodilator with anti-inflammatory properties. It blocks the release of certain chemicals (such as phosphodiesterase, leukotrienes) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways and reduces airway inflammation. This allows the air to pass through more freely through the airways which makes breathing easier.

Q: What is the use of DOXOMONT TABLET?

A: DOXOMONT TABLET is used to treat asthma and chronic obstructive pulmonary disease (COPD). It can also be used to reduce airway inflammation (such as bronchitis), apnea (lack of breathing), seasonal allergic rhinitis (nasal congestion, repeated sneezing, nasal itching or a red, watery and itchy eyes) and other respiratory diseases associated with bronchospasm (tightening of airways).

Q: Can I take DOXOMONT TABLET daily?

A: DOXOMONT TABLET is generally prescribed as two/three doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.

Q: Is DOXOMONT TABLET effective?

A: Yes. DOXOMONT TABLET effectively controls the symptoms of asthma, COPD and other breathing problems, by relaxing the smooth muscles of the airways. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier

Q: What will happen if I consume a high dose of DOXOMONT TABLET than prescribed by my doctor?

A: Do not consume a higher dose of DOXOMONT TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose, is not working for you, consult your doctor for advice.

Q: Is DOXOMONT TABLET safe?

A: DOXOMONT TABLET is considered safe at doses prescribed by the physician. However, it may cause few side effects such as nausea, vomiting, upper stomach pain, headache, irritability, upper respiratory tract infections, lack of sleep, skin rash and fast heartbeat or breathing in some individuals. Contact your doctor if they bother you.

Q: What should I do if I forgot to take a dose of DOXOMONT TABLET?

A: If you forgot to take a dose of DOXOMONT TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of DOXOMONT TABLET to compensate the missed dose.

Q: Will taking a higher dose of DOXOMONT TABLET be more effective?

A: No. Do not take a higher dose of DOXOMONT TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.

Q: I’m pregnant. Can I take DOXOMONT TABLET?

A: DOXOMONT TABLET should be used in pregnant women only if it is considered necessary by the physician. Your doctor will prescribe you with DOXOMONT TABLET after evaluating the risks and benefits of the therapy.

Q: Can DOXOMONT TABLET be used in children?

A: There is no adequate information regarding the use of DOXOMONT TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

Q: Can I stop using DOXOMONT TABLET once my symptoms subside?

A: No. Continue to use DOXOMONT TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.

Q: Can DOXOMONT TABLET be used on an asthma attack?

A: No. DOXOMONT TABLET is only used to prevent or manage the symptoms of asthma. If your asthma or breathing gets worse suddenly, contact your doctor immediately or go to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler for treating your condition.

Q: How to take DOXOMONT TABLET?

A: Take DOXOMONT TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Q: What are the side effects of taking DOXOMONT TABLET?

A: The most common side effects of taking DOXOMONT TABLET are nausea, vomiting, upper stomach pain, headache, irritability, upper respiratory tract infections lack of sleep, skin rash and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.

REFERENCES

1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. Page – 227 & 228.

2. Paola Rogliani, Luigino Calzetta, Josuel Ora, Mario Cazzola & Maria Gabriella Matera. Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis. BMC. Multidisciplinary Respiratory Medicine. August 2019. [Accessed on 15th November 2022]. https://mrmjournal.biomedcentral.com/articles/10.1186/s40248-019-0189-0

3. Saifullah Baig, Rashid Ahmed Khan, Kamran Khan and Nadeem Rizvi. Effectiveness and Quality of Life with Montelukast in Asthma – A double-blind randomized control trial. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. May-June 2019. [Accessed on 29th October 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572966/

4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC) [Revised in September 2020] [Accessed on 27th December 2022]. https://www.medicines.org.uk/emc/files/pil.1243.pdf

5. A.B.C Farmaceutici S.P.A. Doxofylline. [Revised in March 2011] [Accessed on 15th November 2022]. https://www.abcfarmaceutici.it/uploads/news/40_file3_en.pdf

6. Central Drugs Standard Control Organization (CDSCO). Doxofylline MR Tablet 650mg. Doxofylline Tablet (400mg), Doxofylline ER tablets 400mg/800mg (addl. Strength), Doxofylline tablets & Syrup. [Accessed on 27th December 2022]. https://cdscoonline.gov.in/CDSCO/Drugs

6. Doxoford M. Leeford Healthcare Pvt Ltd. [Accessed on 27th December 2022]. https://www.leeford.in/product/943/doxoford-m

PRODUCT DETAILS

    Country Of Origin
    India
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DOXOMONT Tablet 10's

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