DOPACIN 40 Injection 5ml

Heart Failure Rx required
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Best Price* ₹ 36.00 MRP ₹ 40.00
(Inclusive of all taxes) * Mkt: Troikaa Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

DOPACIN 40 INJECTION contains Dopamine which belongs to the group of medicines called Sympathomimetic Agents. It stimulates the heart and improves blood supply to the vital organs such as heart, kidney, brain or gut.

It is used to treat shock (sudden loss of blood supply) and hypotension (low blood pressure) that is caused due to heart attack, open heart surgery, trauma (serious injury), poisoning or kidney failure. It can also restore heart functions in patients suffering from congestive heart failure (heart failure caused due to fluid buildup in the heart).

Before receiving DOPACIN 40 INJECTION, inform your doctor if you have any heart, kidney or liver problems. You must also inform your doctor if you have diabetes, glaucoma, enlarged prostate or thyroid problems.

Patients having an history of circulatory problems (like atherosclerosis, mitral value stenosis, etc.) must be carefully monitored for any changes in skin color or temperature of their fingers or toes after receiving DOPACIN 40 INJECTION. In case of any changes, they must consult their doctor immediately.

DOPACIN 40 INJECTION should not be used in patients with severe irregular or fast heartbeat. It should be used in pregnant or breastfeeding women only if it is considered necessary by the physician.

The most common side effects of receiving DOPACIN 40 INJECTION are irregular heartbeat, changes in blood pressure, dizziness, headache, and difficulty in breathing. Consult your doctor if any of these side effect trouble you. You must also inform your doctor immediately if you experience severe palpitations (racing heartbeat).

USES OF DOPACIN 40 INJECTION

It is used in adults to treat:

  • Shock (sudden decrease in blood flow to the vital organs)
  • Hypotension (low blood pressure)
  • Congestive Heart failure

HOW DOPACIN 40 INJECTION WORKS

DOPACIN 40 INJECTION is a peripheral vasostimulant. It stimulates the heart and relaxes the blood vessels supplying various vital organs (such as heart, kidney, brain and/or gut). This improves blood flow and oxygen supply to these organs which restores heart functions and reduces the risk of other circulatory problems. It also improves blood volume and increases the amount of urine produced by the kidneys.

DIRECTIONS FOR USE

DOPACIN 40 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DOPACIN 40 INJECTION

COMMON

  • irregular, rapid, or slow heart beats
  • chest pain, shortness of breath
  • signs of decrease in blood pressure (such as feel dizzy or faint, particularly when standing up or getting out of bed)
  • nausea or vomiting
  • headache, anxiety, tremor (feeling shaky)
  • increased urination
  • increase in blood sugar levels

UNCOMMON

  • mydriasis (dilation of pupil of the eye)
  • goose pimples (appearance of small points on the skin because you are cold or frightened)
  • high blood pressure

RARE

Contact your doctor immediately if you experience any of the following side effects while or after receiving DOPACIN 40 INJECTION:

  • signs of severe allergic reaction (such as sudden itchy skin rash (hives), swelling of
    the face, lips, mouth or throat, hands, feet, or ankles, which can cause difficulty in
    swallowing or breathing, feeling faint)
  • signs of poor blood circulation in fingers or toes (such as pain and changes in skin color)
  • pain or swelling at the site of injection during or immediately after the injection
  • severe palpitation (fast heartbeat)

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Stick to simple meals. Avoid eating rich or spicy food.

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS

PREGNANCY

DOPACIN 40 INJECTION should be used in pregnant women only if it is considered necessary by the physician. Your doctor will prescribe it to you only when the expected benefits outweigh the potential risk to the fetus. Therefore, inform your doctor before receiving DOPACIN 40 INJECTION if you are pregnant or think you may be pregnant.

BREASTFEEDING

There is no proper information regarding the use of DOPACIN 40 INJECTION during breastfeeding. Therefore, inform your doctor before receiving it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if you experience dizziness or difficulty in seeing in bright light after receiving DOPACIN 40 INJECTION.

ALCOHOL

Avoid consumption of alcohol before receiving DOPACIN 40 INJECTION.

KIDNEY

DOPACIN 40 INJECTION should be used with caution in patients with kidney diseases. Therefore, consult your doctor before receiving it.

LIVER

DOPACIN 40 INJECTION should be used with caution in patients with liver diseases. Therefore, consult your doctor before receiving it.

ALLERGY

Do not receive DOPACIN 40 INJECTION if you are allergic to Dopamine.

HEART DISEASE

DOPACIN 40 INJECTION is not recommended for use in patients who have irregular or fast heartbeats. Therefore, consult your doctor before receiving it.

OTHERS

DOPACIN 40 INJECTION is not recommended for use if you:

  • have a tumor that can increase the blood pressure (Ex. Pheochromocytoma)
  • have an overactive thyroid gland

Before receiving DOPACIN 40 INJECTION, inform your physician if you:

  • have diabetes
  • have a history of circulatory problems (Ex. Atherosclerosis, Mitral value stenosis)
  • have narrow-angle glaucoma (increased pressure in the eyes)
  • have benign prostatic hyperplasia (BPH) with urinary retention

Use in pediatrics:

The safety and effectiveness of DOPACIN 40 INJECTION have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.

Use in geriatrics:

DOPACIN 40 INJECTION should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before receiving it.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving DOPACIN 40 INJECTION, inform your physician if you are taking any of the following medicines such as:

  • general anesthetics (medicines that causes loss of consciousness and sensation) Ex. halothane, isoflurane, cyclopropane, desflurane, enflurane and sevoflurane
  • other medicines used to treat heart problems (Ex. reserpine, propranolol, atenolol, prazosin, digoxin, amiodarone, quinidine)
  • antidepressants (used to treat depression) Ex. fluoxetine, sertraline, paroxetine, isocarboxazid, selegiline, phenelzine, citalopram, escitalopram and amitriptyline
  • phenytoin (a medicine used to treat fits or seizures)
  • ergotamine (a medicine used to treat migraine headache)
  • guanethidine (a medicine used to treat high blood pressure)
  • entacapone (a medicine used to treat Parkinson’s disease)
  • doxapram (used as a respiratory stimulant)
  • metoclopramide (a medicine used to treat gastro-intestinal motility disorders)
  • thyroid hormones (used to treat thyroid deficiencies) Ex. levothyroxine, thyroxine.

Overdosage:

DOPACIN 40 INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual side effects.

SYNOPSIS

Drug :   Dopamine
Pharmacological Category :   Catecholamines
Therapeutic Indication :   Low Blood Pressure, Shock, Congestive Heart Failure
Dosage Forms :   Injection

MORE INFORMATION

  • Keep DOPACIN 40 INJECTION out of reach of children
  • Store DOPACIN 40 INJECTION at room temperature
  • Protect from light and moisture

FAQs ABOUT DOPACIN 40 INJECTION

Can DOPACIN 40 INJECTION be used to treat anaphylactic shock?

DOPACIN 40 INJECTION can be considered as a drug of choice for anaphylactic reactions. It contains dopamine which helps in stimulating the heart and blood vessels. It can restore blood pressure and improve blood circulation to all vital organs. Although, DOPACIN 40 INJECTION can treat anaphylactic shock, you doctor might treat you with other drugs (like adrenaline) depending upon your condition.

Can DOPACIN 40 INJECTION cause fast heart rate?

Yes. DOPACIN 40 INJECTION may make your heartbeat faster. To avoid this, your doctor will constantly monitor your heartbeat while administering DOPACIN 40 INJECTION. However, if you experience any abnormally high heart rate with shortness of breath, inform your doctor immediately.

Can DOPACIN 40 INJECTION cause anxiety?

Yes. DOPACIN 40 INJECTION may make you feel anxious. However, it does not affect every individual. Try to rest and relax. Meditation and breathing exercise can work. If your symptom worsens, please consult your doctor.

Can DOPACIN 40 INJECTION increases blood pressure?

Yes. DOPACIN 40 INJECTION can be used to restore your blood pressure during emergency conditions like shock, heart attack, traumatic injury, blood poisoning etc.

What precautions do I need to follow while taking DOPACIN 40 INJECTION?

Patients receiving DOPACIN 40 INJECTION must inform their doctor about their pre-existing disease condition like diabetes, glaucoma, thyroid problems, liver problems, kidney problems or heart problems. You must also inform your doctor before receiving DOPACIN 40 INJECTION if you have a previous history of circulatory problems. If you are pregnant or breastfeeding, inform your doctor before DOPACIN 40 INJECTION is given to you as a precaution.

Can DOPACIN 40 INJECTION be used on infants?

No. DOPACIN 40 INJECTION is generally used in adults. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.

How long does it take for DOPACIN 40 INJECTION to show its effects?

DOPACIN 40 INJECTION is administered in the vein (intravenously) for faster onset of action. It can start acting within 5 minutes of administration.

Who should avoid taking DOPACIN 40 INJECTION?

DOPACIN 40 INJECTION is not recommended for use in patients having any forms of tumors, overactive thyroid gland or abnormally fast or irregular heart rate. It should be used with caution among patients with diabetes, BPH and liver or kidney disease. Therefore, consult your doctor before receiving it.

Can I take DOPACIN 40 INJECTION to treat BPH?

DOPACIN 40 INJECTION can increase the production of urine and can protect your kidneys from damage caused due to low blood supply. Although, it might reduce few urinary symptoms of benign prostatic hyperplasia (BPH) it cannot be used as a sole agent to treat BPH. Moreover, patients with BPH must inform their doctor before receiving DOPACIN 40 INJECTION.

REFERENCES

1. KD. Tripathi. Drugs acting on ANS. Essentials of medical pharmacology. Seventh edition. 2013. Page – 134.

2. Gerald G. Briggs and Roger K. Freeman. D. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 1353.

3.Thomas Auchet, Marie Alix Regnier, Nicolas Girerd, and Bruno Levy. Outcome of patients with septic shock and high-dose vasopressor therapy. Springer Open. April 2017. [Accessed on 2nd April 2022] https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-017-0261-x

4. Uri Elkayam, Tien M.H. Ng, Parta Hatamizadeh, Munir Janmohamed and Anilkumar Mehra. Renal Vasodilatory Action of Dopamine in Patients with Heart Failure Magnitude of Effect and Site of Action. AHA Journals. January 2008. [Accessed on 21st September 2022] https://www.ahajournals.org/doi/epub/10.1161/CIRCULATIONAHA.107.737106

5. Hospira UK Limited. Electronic Medicines Compendium (EMC). [Revised in January 2022] Accessed on 21st September 2022] https://www.medicines.org.uk/emc/files/pil.3789.pdf

6. Hospira, Inc. U.S. Food & Drug Administration. [Revised in April 2021] [Accessed on 21st September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/018826s047lbl.pdf

7. Martindale Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in July 2018] [Accessed on 21st September 2022] https://www.medicines.org.uk/emc/files/pil.3346.pdf

PRODUCT DETAILS

    Country Of Origin
    India
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