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*10 Tablet(s) in a Strip * Mkt: Ikon Remedies Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout


INTRODUCTION

DOMVENT 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine.

Nausea and vomiting are not a disease but symptoms of different conditions such as infections, food poisoning, motion sickness, overeating, blocked intestine, migraine, indigestion and many more.

DOMVENT 10MG TABLET can also be used for relief of postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn.

DOMVENT 10MG TABLET is not recommended for use in patients having heart or moderate to severe liver diseases, bleeding in the stomach or intestines, blockage or tear in your intestines, and tumors in the pituitary gland (prolactinoma). DOMVENT 10MG TABLET should be used with caution in patients having kidney diseases.

DOMVENT 10MG TABLET should be used with caution in pregnant women and should be used in breastfeeding women only if considered clearly necessary by the doctor. Ask for your doctor’s advice before taking it. DOMVENT 10MG TABLET should be used with caution in elderly patients (above 60 years of age).

DOMVENT 10MG TABLET should not be used in children below 12 years or weighing less than 35kgs. Consult with your child’s doctor. The common side effect of taking DOMVENT 10MG TABLET includes a dry mouth. Consult with your doctor if this worsens or doesn’t improve.

USES OF DOMVENT 10MG TABLET

Prevents nausea and vomiting associated with:

  • central or local origin
  • chemotherapy or radiotherapy
  • drugs
  • migraine

Relieves:

  • postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn

HOW DOMVENT 10MG TABLET WORKS

DOMVENT 10MG TABLET is has an anti-emetic property which acts by blocking a chemical messenger in the brain called dopamine, that transfers information through nerve endings. DOMVENT 10MG TABLET functions by inhibiting the muscle contraction that occurs naturally in the digestive system and enhances the peristaltic movement in the food pipe which helps in facilitating the digestion time faster, this causes calming down effect, thereby relieving nausea or vomiting sensation.

DIRECTIONS FOR USE

Take DOMVENT 10MG TABLET as advised by your physician. It can be taken before meals.

For Tablet, Capsule: Swallow DOMVENT 10MG TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse DOMVENT 10MG TABLET in the specified quantity of water as mentioned on the label. Consume the mixture immediately after reconstitution.

Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and disease condition. Continue to take DOMVENT 10MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.

SIDE EFFECTS OF DOMVENT 10MG TABLET

COMMON

  • dry mouth

UNCOMMON

  • decrease in sexual drive (libido) in men
  • feeling anxious
  • feeling drowsy
  • headaches
  • diarrhoea
  • itchy skin, rash
  • unusual production of breast milk (men and women)
  • painful or tender breasts
  • general feeling of weakness

RARE

Stop taking DOMVENT 10MG TABLET and consult your doctor immediately if you experience any of the following side effects

  • severe allergic reaction having symptoms such as swelling of the hands, feet, ankle, face, lips and throat which may cause difficulty in swallowing or breathing
  • itchy lumpy rash (hives), nettle rash (urticaria)
  • uncontrolled movements, which include irregular movements of eyes, an unusual move of the tongue, abnormal posture (Ex. twisted neck, trembling and muscle stiffness)
  • have a fast unusual heartbeat
  • seizures (fits)

HOW TO MANAGE SIDE EFFECTS

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhoea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if the headache doesn’t improve

Drowsiness:

Take adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the drowsiness doesn’t improve.

Itchy skin:

Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if the itching worsens.

WARNING & PRECAUTIONS

PREGNANCY

DOMVENT 10MG TABLET should be used with caution in pregnant women. Consult your doctor before taking it.

BREASTFEEDING

DOMVENT 10MG TABLET is not recommended for use in breastfeeding women as it may pass through breast milk. DOMVENT 10MG TABLET may cause unwanted side effects affecting the heart in a breastfed baby. It should only be used only if considered clearly necessary by the doctor. Consult your doctor before taking DOMVENT 10MG TABLET.

DRIVING AND USING MACHINES

DOMVENT 10MG TABLET does not affect the ability to drive or use machines. Yet do not drive or operate any machines if you feel dizzy after taking DOMVENT 10MG TABLET.

KIDNEY

DOMVENT 10MG TABLET should be taken with caution in patients with kidney problems such as kidney impairment or kidney failure. Your doctor might consider adjusting your dose. Consult your doctor before taking it.

ALLERGY

Do not take DOMVENT 10MG TABLET if you are allergic to domperidone or any other ingredients present in it.

HEART DISEASE

DOMVENT 10MG TABLET is not recommended in patients suffering from heart problems such as prolonged QT corrected interval (reading in eco cardiogram (ECG) machine) or heart failure (heart cannot pump blood properly). Kindly consult a doctor before taking DOMVENT 10MG TABLET.

OTHERS

DOMVENT 10MG TABLET is not recommended for use if you:

  • tumor in the pituitary gland (prolactinoma)
  • history of blockage or tear in the intestine
  • hypokalemia (low level of potassium)
  • hyperkalemia (high level of potassium in the blood)
  • hypomagnesemia (low level of magnesium in the blood)
  • signs and symptoms of bleeding in the stomach or intestine (black tarry bowel motions or blood in your bowel motions)

Use in pediatrics:

DOMVENT 10MG TABLET is not recommended for use in children below 12 years of age or weighing less than 35 kgs. Consult with your child’s doctor before giving DOMVENT 10MG TABLET to your child.

Use in geriatrics:

DOMVENT 10MG TABLET should be used with caution for use over 60 years of age, as DOMVENT 10MG TABLET be associated with an increased risk of heart rhythm disorder and cardiac arrest. Consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking DOMVENT 10MG TABLET, inform your doctor if you are taking any of the following medicines:

  • medicines to treat fungal infections (Ex. ketoconazole, fluconazole, and voriconazole)
  • medicines to treat bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine)
  • medicine to treat heart problems or high blood pressure (Ex. amiodarone, dronedarone, quinidine, disopyramide, bepridil, dofetilide, sotalol, diltiazem, verapamil)
  • medicines to treat psychoses (Ex. haloperidol, pimozide, sertindole), medicine to treat depression (Ex. citalopram, escitalopram)
  • medicines to treat gastrointestinal disorders (such as cisapride, diphemanil, dolasetron, prucalopride)
  • medicines to treat allergies (Ex. mequitazine, mizolastine)
  • medicine to treat malaria (specifically halofantrine)
  • medicines to treat AIDS/HIV (Ex. ritonavir, atazanavir)
  • medicine to treat cancer (Ex. toremifene, vandetanib, vincamine)
  • medicine used to treat drug addiction (Ex. methadone)

Overdosage:

If you or anyone else accidentally took too much of DOMVENT 10MG TABLET, consult your doctor immediately. The symptoms might include feeling sleepy, confused, uncontrolled movements of the eye and tongue and abnormal posture (like a twisted neck).

SYNOPSIS

Drug :   Domperidone
Pharmacological Category :   Dopamine antagonists
Therapeutic Indication :   Nausea and Vomiting          
Dosage Forms :  

Tablets, Capsules, Dispersible tablets, Rapitab, Suspension, Oral Suspension, Syrup, Oral Drops, Drops 

MORE INFORMATION

  • Keep DOMVENT 10MG TABLET out of reach of children
  • Store DOMVENT 10MG TABLET at room temperature below 30°C

FAQs ABOUT DOMVENT 10MG TABLET

What is DOMVENT 10MG TABLET and why is it prescribed?

DOMVENT 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine. DOMVENT 10MG TABLET can also be used in relief of postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn.

How long can I take DOMVENT 10MG TABLET?

It is recommended that DOMVENT 10MG TABLET be taken for the shortest period and at the lowest dose. This is because DOMVENT 10MG TABLET can cause an irregular heartbeat when taken for a longer period or at a high dose. Ask for your doctor’s advice.

Can I take DOMVENT 10MG TABLET with antibiotics?

Use of DOMVENT 10MG TABLET with antibiotics like erythromycin, levofloxacin, and some antifungals is not recommended as this can cause interaction. Please consult your doctor for advice before using any antibiotics with DOMVENT 10MG TABLET.

Does DOMVENT 10MG TABLET increase milk secretion?

Yes, DOMVENT 10MG TABLET can increase milk secretion also known as galactorrhoea. This is an uncommon side effect of using DOMVENT 10MG TABLET. Talk to your doctor if you are experiencing this side effect while taking this medicine.

Does DOMVENT 10MG TABLET cause heart problems?

DOMVENT 10MG TABLET may be associated with an increased risk of heart problems (like an irregular heartbeat) and heart attacks. The risk also increases when DOMVENT 10MG TABLET is given together with other medicines.  Inform the doctor of your medication history when taking DOMVENT 10MG TABLET.

Does DOMVENT 10MG TABLET cause dry mouth?

Yes, DOMVENT 10MG TABLET can cause dry mouth. A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

What is the best time to take DOMVENT 10MG TABLET?

It is recommended to take DOMVENT 10MG TABLET before meals. If taken after meals, absorption of the medicine is somewhat delayed. Patients should try to take each dose of DOMVENT 10MG TABLET at a scheduled time to avoid missing a dose.

REFERENCES

What is DOMVENT 10MG TABLET and why is it prescribed?

DOMVENT 10MG TABLET contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in the prevention of nausea and vomiting associated with central or local origin, chemotherapy or radiotherapy, drugs or migraine. DOMVENT 10MG TABLET can also be used in relief of postprandial symptoms of fullness, nausea, epigastric bloating and belching (burping) that is occasionally accompanied by stomach discomfort and heartburn.

How long can I take DOMVENT 10MG TABLET?

It is recommended that DOMVENT 10MG TABLET be taken for the shortest period and at the lowest dose. This is because DOMVENT 10MG TABLET can cause an irregular heartbeat when taken for a longer period or at a high dose. Ask for your doctor’s advice.

Can I take DOMVENT 10MG TABLET with antibiotics?

Use of DOMVENT 10MG TABLET with antibiotics like erythromycin, levofloxacin, and some antifungals is not recommended as this can cause interaction. Please consult your doctor for advice before using any antibiotics with DOMVENT 10MG TABLET.

Does DOMVENT 10MG TABLET increase milk secretion?

Yes, DOMVENT 10MG TABLET can increase milk secretion also known as galactorrhoea. This is an uncommon side effect of using DOMVENT 10MG TABLET. Talk to your doctor if you are experiencing this side effect while taking this medicine.

Does DOMVENT 10MG TABLET cause heart problems?

DOMVENT 10MG TABLET may be associated with an increased risk of heart problems (like an irregular heartbeat) and heart attacks. The risk also increases when DOMVENT 10MG TABLET is given together with other medicines.  Inform the doctor of your medication history when taking DOMVENT 10MG TABLET.

Does DOMVENT 10MG TABLET cause dry mouth?

Yes, DOMVENT 10MG TABLET can cause dry mouth. A dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

What is the best time to take DOMVENT 10MG TABLET?

It is recommended to take DOMVENT 10MG TABLET before meals. If taken after meals, absorption of the medicine is somewhat delayed. Patients should try to take each dose of DOMVENT 10MG TABLET at a scheduled time to avoid missing a dose.


REFERENCES

1. KD Tripathi. Antiemetics. Essentials of Medical Pharmacology. Eighth edition. 2019. Page - 414.

2. Rhew K, Han N, Oh JM. Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. August 2019. [Accessed on 3rd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719182/

3. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubchem. Domperidone. [Accessed on 3rd November 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone

4. Savio C Reddymasu, Irfan Soykan, Richard W McCallum. Domperidone: review of pharmacology and clinical applications in gastroenterology. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. September 2007. [Accessed on 3rd November 2022] https://pubmed.ncbi.nlm.nih.gov/17488253/

5. S.C. Zentiva S.A. Electronic Medicines Compendium (emc). [Revised in April 2021] [Accessed on 3rd November 2022] https://www.medicines.org.uk/emc/files/pil.4177.pdf

6. Torrent Pharmaceuticals Ltd. Domstal DT (Domperidone). [Revised in February 2022]. [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/3082.pdf

7. Torrent Pharmaceuticals Ltd. Domstal (Domperidone). [Revised in April 2022]. [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1623.pdf

8. Torrent Pharmaceuticals Ltd. Domstal OD (Domperidone). [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/408.pdf

9. Janssen-Cilag (New Zealand) Ltd. Medsafe. [Revised in November 2020]. [Accessed on 3rd November 2022] https://www.medsafe.govt.nz/profs/Datasheet/m/motiliumtab.pdf

10. Morepen Laboratories Ltd. DOM DT 20mg, DOM DT 5mg [Accessed on 03rd November 2022] https://www.morepen.com/medicus/antibiotics

USEFUL DIAGNOSTIC TESTS

  • Whole Abdomen Ultrasound

AUTHOR DETAILS

Written By Dr. Priyanka Goel, BDS
Last updated on 10 Nov 2022 | 04:39 PM(IST)

PRODUCT DETAILS

    Country Of Origin
    India
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