INTRODUCTION
DIPROBATE S LOTION is a combination of Betamethasone and Salicylic acid which belongs to the group of medicines called Topical Corticosteroids and Keratolytic agents respectively. It is used to treat subacute and chronic hyperkeratotic and dry skin diseases which respond to external topical steroid therapy. These conditions include psoriasis, keratosis palmaris et plantaris (keratinisation of the palm of the hand and the sole of the foot), chronic eczema or allergic skin diseases, endogenous eczema/atopic dermatitis, seborrhoeic eczema, dyshidrosis lemellosa sicca (itching, dry, squamous vesicles on palms of the hand, sides of fingers or foot-soles), lichen planus, lichen simplex and ichthyosis.
Before using DIPROBATE S LOTION your doctor may want to check your treatment regularly if you have a skin condition called psoriasis, or if you are having any raised bumps filled with pus under your skin. You are not recommended to smoke or go near naked flames while using DIPROBATE S LOTION as it may cause serious fire hazards. DIPROBATE S LOTION during pregnancy and lactation should only be considered if the expected benefit to the mother outweighs the risk to the foetus. Consult your doctor before using.
DIPROBATE S LOTION is not recommended in children under 1 year of age. Consult your doctor before using. It should be used with caution in elderly people. The common side effects of using DIPROBATE S LOTION are pruritus, local skin burning and skin pain. Consult your doctor if any of these symptoms bothers or persists for a longer duration.
USES OF DIPROBATE S LOTION
It is used to treat various skin condition such as :
- psoriasis
- keratosis palmaris et plantaris
- chronic eczema or allergic skin diseases
- endogenous eczema/atopic dermatitis
- seborrhoeic eczema
- dyshidrosis lemellosa sicca (itching, dry, squamous vesicles on palms of the hand, sides of fingers or foot-soles)
- lichen planus and lichen simplex
- ichthyosis
HOW DIPROBATE S LOTION WORKS
DIPROBATE S LOTION is a combination of Betamethasone and Salicylic acid. Betamethasone works by blocking the production of certain inflammatory mediators called prostaglandins in the body and thus reduces the redness and swelling. It has anti-inflammatory proteins which are responsible for removing the scaly layers of the skin and reduces the redness and itchiness caused by the various skin problems. Salicylic acid prevents the skin lesions by peeling the outer layer of the skin and helps to re-establish the normal skin by removing the dead skin. It also promotes the fast absorption of betamethasone into the skin.
DIRECTIONS FOR USE
Apply DIPROBATE S LOTION as directed by your physician. It is for external use only. Apply thin layer of this medicine on the affected area. Treated areas on the face need not be covered with a plaster or bandage. Avoid applying this medicine around your eyes, including eyelids, nose and mouth. Your doctor will prescribe the right dose depends on your age, body weight and severity of infection.
SIDE EFFECTS OF DIPROBATE S LOTION
COMMON
- pruritus
- local skin burning
- skin pain
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredDIPROBATE S LOTION during pregnancy should only be considered if the expected benefit to the mother outweighs the risk to the foetus. Consult your doctor before using.
BREASTFEEDING
Monitoring requiredDIPROBATE S LOTION during lactation should only be considered if the expected benefit to the mother outweighs the risk to the infant. Consult your doctor before using.
KIDNEY
Use with CautionDIPROBATE S LOTION should be used with caution in patients with kidney problems. It should be used for the shortest duration to achieve the desired clinical benefit. Consult your doctor before using.
LIVER
Use with CautionDIPROBATE S LOTION should be used with caution in patients with liver problems. It should be used for the shortest duration to achieve the desired clinical benefit. Consult your doctor before using.
ALLERGY
ContraindicatedDo not use DIPROBATE S LOTION of you are allergic to Betamethasone, Salicylic acid or any other ingredients of this medicine.
USE IN PEDIATRICS
ContraindicatedDIPROBATE S LOTION is not recommended for use in children below 1 year of age. Consult your doctor before using.
USE IN GERIATRICS
Use with CautionDIPROBATE S LOTION should be used with caution in elderly patients. Consult your doctor before using
OTHERS
DIPROBATE S LOTION is not recommended for use if you:
- have rosacea
- have acne vulgaris
- have pruritis without inflammation
- have perianal and genital pruritis
- have perioral dermatitis
- have primary infected skin lesions caused by infection with fungi, viruses or bacteria
- have ulcerated skin lesions
- have a child with dermatoses (in children under one year of age, including dermatitis and napkin eruptions)
INTERACTIONS
A. Drug-Drug interactions:
Before using DIPROBATE S LOTION, inform your doctor if you are taking any of the following medicines:
- ritonavir (used to treat HIV infection)
- itraconazole (used to treat fungal infection)
Overdosage:
If you or anyone else accidentally uses too much of DIPROBATE S LOTION, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Betamethasone, Salicylic acid |
| Pharmacological Category | : | Topical Corticosteroids, Keratolytic agents |
| Therapeutic Indication | : | Skin infections |
| Dosage Forms | : | Cream, Lotion, Ointment |
MORE INFORMATION
- Keep DIPROBATE S LOTION out of reach of children
- Store below 25°C
FAQs ABOUT DIPROBATE S LOTION
Q: How DIPROBATE S LOTION works?
A: DIPROBATE S LOTION is a combination of Betamethasone and Salicylic acid. Betamethasone works by blocking the production of certain inflammatory mediators called prostaglandins in the body and thus reduces the redness and swelling. It has anti-inflammatory proteins which are responsible for removing the scaly layers of the skin and reduces the redness and itchiness caused by the various skin problems. Salicylic acid prevents the skin lesions by peeling the outer layer of the skin and helps to re-establish the normal skin by removing the dead skin. It also promotes the fast absorption of betamethasone into the skin.
Q: How to use DIPROBATE S LOTION?
A: Always apply DIPROBATE S LOTION as directed by your physician. Apply a thin layer of this medicine on the affected area. Treated areas on the face need not be covered with a plaster or bandage. Do not use this medicine on your face for more than 5 days. Avoid applying this medicine around your eyes, including eyelids, nose and mouth.
Q: What are the common side effects of DIPROBATE S LOTION?
A: The most common side effects of DIPROBATE S LOTION are dryness and scaling, burning, stinging, itchy skin and skin pain. Consult your doctor if any of these symptoms bothers you.
Q: Is DIPROBATE S LOTION safe to use in children?
A: DIPROBATE S LOTION is not recommended for use in children below 1 year of age. In children under 12 years of age, long-term continuous topical corticosteroid therapy should be avoided where possible, as adrenal suppression can occur. Consult your doctor before using this medicine.
REFERENCES
1. KD. Tripathi: Drugs acting on skin and mucous membrane. Essentials of medical pharmacology. Eighth edition. 2019. Page –949,954.
2. Fred F. Ferri MD. Betamethasone Dipropionate. [Accessed on 31st May 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/betamethasone-dipropionate
3. Organon Pharma (UK) Limited, 2022 (EMC). [Revised in March 2022] [Accessed on 31st May 2022] https://www.medicines.org.uk/emc/files/pil.1450.pdf
4. Betamethasone Dipropionate + Salicyclic acid Lotion (Indications). Central Drugs Standard Control Organization. October 2009. [Accessed on 31st May 2022] https://cdscoonline.gov.in/CDSCO/Drugs
5. Cipla med. Saslic /saslic DS facewash. [Revised in January 2010] [Accessed on 31st May 2022] https://www.ciplamed.com/content/saslic-saslic-ds-facewash
6. Glaxosmithkline Pharmaceuticals Ltd. [Revised in April 03, 2018] [Accessed on 31st May 2022] https://india-pharma.gsk.com/media/6350/betnovate-skin-cream.pdf
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