Dilgel Gel 30gm

Haemorrhoid Rx required
OUT OF STOCK

Best Price*  ₹ 78.48
MRP ₹98.10
(Inclusive of all taxes) * Mfr: Cadila Pharmaceuticals Ltd * Country of Origin: India



INTRODUCTION

DILGEL contains diltiazem which belongs to a group of medicines called calcium-channel blockers. It is used to promote healing and reduce the pain in anal fissure. An anal fissure is a small cut or tear that has occurred in the skin inside your anus. Symptoms may include severe and sharp pain, irritation and tenderness. Certain fissures may heal quickly, while others can take several months to heal.

Local application of DILGEL causes inhibition of extracellular calcium influx across the smooth muscle cell membranes present on the application site (anus). This reduced intracellular calcium concentrations will increase muscle relaxation and reduces pressure and increases blood flow to the area to allow healing to occur.

The most common side effects of taking this medicine are headache, light-headedness or dizziness, local itching, soreness or rectal bleeding. Your doctor will let you know how long you should continue treatment for. In most cases this will be for six to eight weeks. Apply the gel just inside and around the anus (back passage) as instructed by your doctor. A finger covering such as cling film, disposable glove or finger cot may be used to apply the gel.

USES OF DILGEL

  • Anal fissure (a tear in the skin of the lower half of the anal canal)

HOW DILGEL WORKS

Local application of DILGEL causes inhibition of extracellular calcium influx across the smooth muscle cell membranes present on the application site (anus). This reduced intracellular calcium concentrations will increase muscle relaxation and reduces pressure and increases blood flow to the area to allow healing to occur.

DIRECTIONS FOR USE

Use the gel twice daily (morning and evening) or as directed by your doctor. It is for external use only. Wash your hands before and after application of the cream to ensure hygiene is maintained. Apply the gel just inside and around the anus (back passage) as instructed by your doctor. A finger covering such as cling film, disposable glove or finger cot may be used to apply the gel.

SIDE EFFECTS OF DILGEL

COMMON

  • headache
  • light-headedness or dizziness
  • local itching, soreness or rectal bleeding

HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol.

Light-headedness or dizziness:

Try to rest and relax. Eat simple meals. Do not drive or operate any machinery while you are feeling dizzy.

WARNING & PRECAUTIONS

PREGNANCY

DILGEL should be used with caution in pregnant women. Consult your doctor before using this medicine.

BREASTFEEDING

DILGEL should be used with caution in breastfeeding women. Consult your doctor before using this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any tools or machines if your ability is affected by this medicine.

ALLERGY

Do not use this medicine if you are allergic (hypersensitive) to diltiazem or any other ingredients in this medicine.

HEART DISEASE

DILGEL should be used with caution in patients having high blood pressure or any other heart disease. Consult your doctor before taking.

INTERACTIONS

Talk to your doctor, if you are using,

  • medicines used to treat high blood pressure such as doxazosin, tamsulosin, atenolol, propranolol or acebutolol
  • medicines used to treat angina (such as glyceryl trinitrate or isosorbide trinitrate)

SYNOPSIS

Drug :   Diltiazem
Pharmacological Category :   Calcium channel blockers
Therapeutic Indication :   Anal fissures
Dosage Forms :   Tablet, Capsule, Topical gel, Injection

MORE INFORMATION

Store DILGEL at temperaure not exceeding 25ºC

FAQs ABOUT DILGEL

Can DILGEL cause dizziness?

Yes. This medicine can cause dizziness in some individuals, although not everybody gets them. Try to rest and relax. Eat simple meals. Do not drive or operate any machinery while you are feeling dizzy.

What are the uses of DILGEL?

It is used to treat anal fissure (a tear in the skin of the lower half of the anal canal).

REFERENCES

1. Gerald G. Briggs and Roger K. Freeman. D. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 1184-1186.

2. Ventrus Biosciences, Inc. Efficacy and Safety Study with Diltiazem Hydrochloride Cream to Treat Anal Fissures. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on January 2014] [Accessed 23rd November 2020] https://clinicaltrials.gov/ct2/show/NCT01690221

3. Bikash Medhi, Ajay Prakash, Sujata Upadhyay, Deonis Xess, T. D. Yadav and L. Kaman. Comparison of Observational and Controlled Clinical Trials of Diltiazem in the Treatment of Chronic Anal Fissure. NCBI; PMC US National Library of Medicine, National Institute of Health. October 2011. [Accessed 23rd November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236256/

4. NHS. Guy’s and St. Thomas. NHS foundation trust. Diltiazem hydrochloride 2% cream. [Revised on June 2020] [Accessed 23rd November 2020] https://www.guysandstthomas.nhs.uk/resources/patient-information/pharmacy/diltiazem-hydrochloride-2-cream.pdf

5. Chesterfield Royal Hospital. NHS foundation trust. Diltiazem 2% hydrochloride cream. [Revised on August 2017] [Accessed 23rd November 2020] https://www.chesterfieldroyal.nhs.uk/application/files/8815/4142/8195/Diltiazem_2_Hydrochloride_Cream.pdf

Manufacturer/Marketer Details

    Net Qty
    1
    Shelf Life
    NA
    Item Weight
    40
    No. of Units in a Kit
    NA
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