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Best Price* ₹ 107.14 MRP ₹ 133.92
(Inclusive of all taxes) *10 Capsule(s) in a Strip * Mkt: ZENVITA HEALTHCARE PVT LTD * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

DEX RABATO DSR CAPSULE is a combination of Domperidone and Dexrabeprazole which belongs to the group of medicines called Prokinetic Drugs and Proton pump inhibitors respectively. It is used to treat stomach ulcers (gastric or peptic ulcers) and gastroesophageal reflux disease (GERD; acid reflux causing irritation of food pipe).

It can also be used to reduce the signs of acidity, heartburn, indigestion, burping or bloating. It is typically used among patients who are not responding adequately to therapy with dexrabeprazole alone.

DEX RABATO DSR CAPSULE should be taken at least 15-30 minutes before meals. During treatment with DEX RABATO DSR CAPSULE your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects.

Before taking DEX RABATO DSR CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones.

DEX RABATO DSR CAPSULE is not recommended for use in patients having bleeding from the gut. It is also not suitable for use in pregnant or breastfeeding women. The most common side effects of taking DEX RABATO DSR CAPSULE are dry mouth, cough, sore throat, runny nose, diarrhea, constipation, stomach pain, flatulence and increased signs of infections. Consult your doctor if any of these side effect bothers you.

USES OF DEX RABATO DSR CAPSULE

It is used to treat:

  • Stomach ulcers (gastric or peptic ulcers)
  • Gastrointestinal Reflux disease (GERD; acid reflux causing irritation of food pipe)
  • Nausea and Vomiting
  • Acidity, Heartburn
  • Signs of indigestion (such as burping, bloating)

HOW DEX RABATO DSR CAPSULE WORKS

DEX RABATO DSR CAPSULE contains two medicines namely domperidone and Dexrabeprazole. Domperidone stimulates the gut and speeds up the movements of food from the stomach into the intestines. This action reduces chances for acid reflux and prevents the irritation of food pipe. It also blocks the transmission of nerve signals between the vomiting centers and brain which reduces the onset of nausea and vomiting.

Dexrabeprazole is a proton pump inhibitor. It reduces gastric acid secretion which promotes the healing of ulcers and esophageal lesions. It also provides relief from the unpleasant symptoms of the GI tract (such as acidity, bloating, burping and indigestion).

DIRECTIONS FOR USE

Take DEX RABATO DSR CAPSULE 15-30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking DEX RABATO DSR CAPSULE unless your doctor advice you to stop.

SIDE EFFECTS OF DEX RABATO DSR CAPSULE

COMMON

  • benign polyps in the stomach
  • dry mouth
  • cough, sore throat, runny nose
  • diarrhea, constipation, stomach pain, flatulence
  • nausea or vomiting
  • body pain, back pain
  • feeling weak
  • sleeplessness
  • headache, dizziness
  • increased infections

UNCOMMON

  • low sex drive
  • drowsiness, sleepiness
  • anxiety, nervousness
  • blocked sinuses
  • breast milk production in men and women
  • breast pain or tenderness
  • fragile bones (risk of bone fracture)
  • indigestion, belching
  • skin rash, redness or itching
  • muscle pains, joint pains, leg cramps
  • urinary tract infection

RARE

  • low WBC and platelet counts
  • loss of appetite
  • depression
  • problems in vision
  • stomach upset, mouth ulcers, taste disturbance
  • weight gain
  • kidney problems

Stop taking DEX RABATO DSR CAPSULE and inform your doctor immediately if you experience any of the following side effects such as:

  • severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
  • severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
  • signs of bleeding in the gut (such as bloody vomits/stools)
  • frequent infections, flu-like symptoms, sore throat, mouth ulcers
  • increased bleeding tendency
  • fast or irregular heartbeat, difficulty in breathing, feeling faint
  • fits
  • uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture
  • signs of kidney problems (such as low urine output, bloody urine, fever, rash and joint stiffness)
  • signs of infectious diarrhea (severe persistent watery diarrhea with severe stomach pain and fever)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try to take DEX RABATO DSR CAPSULE with or just after meals. Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if nausea worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Constipation:

Taking DEX RABATO DSR CAPSULE with meals may reduce the chances of constipation. However, if you experience constipation, eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

WARNING & PRECAUTIONS

PREGNANCY

DEX RABATO DSR CAPSULE is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.

BREASTFEEDING

DEX RABATO DSR CAPSULE is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or handle heavy tools or machines if your ability is affected by DEX RABATO DSR CAPSULE.

ALCOHOL

Avoid consumption of alcohol while taking DEX RABATO DSR CAPSULE, as it could aggravate your existing condition.

KIDNEY

DEX RABATO DSR CAPSULE should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

LIVER

DEX RABATO DSR CAPSULE should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take DEX RABATO DSR CAPSULE if you are allergic to Domperidone, Dexrabeprazole or to any other proton pump inhibitors (such as rabeprazole, omeprazole).

HEART DISEASE

DEX RABATO DSR CAPSULE is not recommended for use in patients with heart problems such as prolongation of QT interval or congestive heart failure. Therefore, consult your doctor before taking it.

OTHERS

DEX RABATO DSR CAPSULE is not recommended for use if you:

  • have bloody stools or bleeding in the gut
  • have blockage or tear in the intestines
  • have severe fluid or electrolyte disturbances
  • have prolactinoma (a non-cancerous tumor of pituitary gland)
  • have low blood potassium or magnesium levels

Before taking DEX RABATO DSR CAPSULE inform your doctor if you:

  • have osteoporosis
  • have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
  • are going to test Chromogranin A level
  • have tumor in the stomach

Use in Pediatrics:

DEX RABATO DSR CAPSULE is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use in Geriatrics:

DEX RABATO DSR CAPSULE should be used with caution in elderly patients (aged 65 years and above). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking DEX RABATO DSR CAPSULE inform your doctor if you are taking any of the following medicines such as:

  • other medicines used to treat gastrointestinal problems (Ex. cisapride, dolasetron, prucalopride, diphemanil)
  • medicines used to treat heart problems or hypertension (Ex. digoxin, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem or verapamil)
  • medicines used to treat HIV infection (Ex. atazanavir, nelfinavir, saquinavir)
  • medicines used to treat fungal infections (such as ketoconazole, itraconazole, posaconazole)
  • antipsychotics (used to treat mental illness) Ex. haloperidol, pimozide, sertindole
  • antidepressants (used to treat depression) Ex. escitalopram or citalopram, fluvoxamine, St John’s wort
  • antibiotics (used to treat bacterial infections) Ex. moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin or amoxicillin
  • medicines used to treat malaria (Ex. halofantrine, lumefantrine)
  • antihistamines (used to treat allergies) Ex. mizolastine, mequitazine
  • medicines used to treat cancer (Ex. toremifene, vandetanib, vincamine, erlotinib, dasatinib, nilotinib)
  • methotrexate (used to treat cancer and auto-immune disease)
  • bepridil (used to treat hypertension)
  • methadone (used to relieve pain)
  • apomorphine (a medicine used to reduce abnormal muscle movements)

Overdosage:

If you or anyone else accidentally took more DEX RABATO DSR CAPSULE, contact your doctor immediately or go to a hospital straight away. Symptoms of overdosage might include sleepiness, confusion, uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture.

SYNOPSIS

Drug :   Domperidone, Dexrabeprazole
Pharmacological Category :   Dopamine (D2) Receptor antagonists, Proton Pump Inhibitors
Therapeutic Indication :   Peptic ulcer, GERD
Dosage Forms :   Tablet, Capsule

MORE INFORMATION

  • Keep DEX RABATO DSR CAPSULE out of the sight and reach of children
  • Store DEX RABATO DSR CAPSULE at room temperature

FAQs ABOUT DEX RABATO DSR CAPSULE

What is DEX RABATO DSR CAPSULE used for?

DEX RABATO DSR CAPSULE is used to treat peptic ulcers and GERD. It can also be used to treat nausea, vomiting, bloating, burping, acidity and heartburn.

How and when to take DEX RABATO DSR CAPSULE?

Take DEX RABATO DSR CAPSULE at least 15-30 minutes before meals. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

How long should I take DEX RABATO DSR CAPSULE?

You need to take DEX RABATO DSR CAPSULE for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition

What is the best time to take DEX RABATO DSR CAPSULE?

DEX RABATO DSR CAPSULE must be taken before meals to avoid gastrointestinal side effects.

What to do if I forgot to take a dose of DEX RABATO DSR CAPSULE?

If you forgot to take a dose of DEX RABATO DSR CAPSULE, take it as soon as you remember. However, if it is time for the next dose of DEX RABATO DSR CAPSULE, skip the missed dose and take the next one regularly. Do not take a double dose of DEX RABATO DSR CAPSULE to compensate the missed ones.

What are the most common side effects of taking DEX RABATO DSR CAPSULE?

The most common side effects of taking DEX RABATO DSR CAPSULE are dry mouth, cough, sore throat, runny nose, diarrhea, constipation, stomach pain, flatulence and increased signs of infections. Consult your doctor if any of these side effect bothers you.

Can I stop taking DEX RABATO DSR CAPSULE without consulting your doctor?

No. You should not stop taking DEX RABATO DSR CAPSULE without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using DEX RABATO DSR CAPSULE, consult your doctor for advice.

Will taking a higher dose of DEX RABATO DSR CAPSULE be more effective?

No, taking a higher dose of DEX RABATO DSR CAPSULE will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

What precautions do I need to follow while taking DEX RABATO DSR CAPSULE?

Make sure to take DEX RABATO DSR CAPSULE 30 minutes before meals. Before taking DEX RABATO DSR CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones. Do not take DEX RABATO DSR CAPSULE without consulting your doctor if you are pregnant or breastfeeding. Regularly visit your doctor and take all the blood tests recommended by your him/her without fail.

Can I take medication for high blood pressure along with DEX RABATO DSR CAPSULE?

It is not advisable to take medicines to control blood pressure while taking DEX RABATO DSR CAPSULE without consulting your doctor as they have known interactions with this medicine.

Can DEX RABATO DSR CAPSULE be used in pregnant women?

DEX RABATO DSR CAPSULE is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.

How to take DEX RABATO DSR CAPSULE?

You must take DEX RABATO DSR CAPSULE as advised by your physician. Try to take DEX RABATO DSR CAPSULE 30 minutes before and swallow it with a glass of water. Do not crush or chew the medicine.

How much DEX RABATO DSR CAPSULE should I take?

DEX RABATO DSR CAPSULE should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

Can DEX RABATO DSR CAPSULE cause constipation?

Yes. Constipation is a common side effect of using DEX RABATO DSR CAPSULE. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if this side effect bothers you.

Can DEX RABATO DSR CAPSULE cause dry mouth?

Yes. Dry mouth is a common side effect of using DEX RABATO DSR CAPSULE. Contact your doctor if this side effect bothers you.

REFERENCES

1. KD. Tripathi. Antiemetic, Prokinetic and Digestant drugs & Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of medical pharmacology. Seventh edition. 2013. Page – 666 & 653.

2. Nur Fathurah Zamani, Afifah Sjamun Sjahid, Tuan Hairulnizam Tuan Kamauzaman, Yeong Yeh Lee and Md Asiful Islam. Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Journal of Clinical Medicine. August 2022. [Accessed on 17th December 2022]. https://www.mdpi.com/2077-0383/11/18/5268/htm

3. Balkanpharma Dupnitsa AD. Electronic Medicines Compendium (EMC). [Revised in September 2022]. [Accessed on 17th December 2022]. https://www.medicines.org.uk/emc/files/pil.2842.pdf

4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in March 2021]. [Accessed on 17th December 2022]. https://www.medicines.org.uk/emc/files/pil.556.pdf

5. Hetero Healthcare Pvt Ltd. Dirab D 30mg Capsule. [Accessed on 17th December 2022]. https://www.heterohealthcare.com/dirab-d-30-capsule

6. Central Drugs Standard Control Organization. Dexrabeprazole 10mg (EC) + Domperidone 30mg SR Capsules. June 2008. [Accessed on 17th December 2022]. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf

7. Texas Pharmaceutical Private Limited. Dextop DSR (Dexrabeprazole 10mg+Domperidone 30mg). [Accessed on 17th December 2022]. https://www.texasusa.in/product/dextop-dsr/

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    DEXRABEPRAZOLE 10 mg+DOMPERIDONE 30 mg
    Hsn Code
    30049039
ALTERNATE BRANDS
DEXOL D Capsule 10's
Prescription Ulcer/Reflux/Flatulence Rx required
Rs.79.00
DEXLET D Capsule 10's
Prescription Ulcer/Reflux/Flatulence Rx required
Rs.115.00
DEXTOP DSR Capsule 10's
Prescription Ulcer/Reflux/Flatulence Rx required
Rs.115.00
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