Deplatt CV Forte 75/20/150mg Capsule 10'S

Blood Clot Rx required

Best Price* ₹ 56.72 MRP ₹ 70.90
(Inclusive of all taxes) *10 Capsule(s) in a Strip * Mkt: Torrent Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

DEPLATT CV FORTE 75/20/150MG CAPSULE is a combination of Aspirin, Clopidogrel and Atorvastatin which belongs to the group of medicines called Antiplatelets and HMG-CoA reductase inhibitors respectively. DEPLATT CV FORTE 75/20/150MG CAPSULE is indicated in the treatment of patients with percutaneous coronary intervention (PCI) and myocardial infarction (also known as heart attack which occurs when blood flow to the heart muscle is blocked or interrupted).

Percutaneous coronary intervention (also known as angioplasty with stent) is a non-surgical procedure used among patients with heart problems (such as cardiogenic shock, acute severe heart failure or ischemic symptoms) to unclog blood vessels in the heart that have been narrowed by plaque buildup by placing a stent.        

Along treatment with DEPLATT CV FORTE 75/20/150MG CAPSULE follow a healthy low-fat diet as advised by your doctor to achieve better results. Avoid drinking alcohol during treatment with DEPLATT CV FORTE 75/20/150MG CAPSULE, as it could increase the risk of bleeding in the gastrointestinal tract.    

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in patients with severe liver or kidney disease, recent ischemic stroke, gout, active or recurrent peptic ulcer with or without gastrointestinal bleeding and bleeding disorders (such as bleeding in the brain or hemophilia).

DEPLATT CV FORTE 75/20/150MG CAPSULE is generally not recommended for use in pregnant or breastfeeding women and in children or adolescents (aged below 18 years). It should be used with caution in elderly patients (aged 70 years or above) because of increased risk of gastro-intestinal bleeding.

The most common side effects of taking DEPLATT CV FORTE 75/20/150MG CAPSULE are increased bleeding tendency, nausea, indigestion, diarrhea, stomach pain, constipation, muscle pain, dizziness and headache. Consult your doctor if any of these side effects worsen.  

USES OF DEPLATT CV FORTE 75/20/150MG CAPSULE

  • Treats patients with percutaneous coronary intervention (PCI) and myocardial infarction

HOW DEPLATT CV FORTE 75/20/150MG CAPSULE WORKS

DEPLATT CV FORTE 75/20/150MG CAPSULE effectively improves cardiac function and reduces the risk of heart problems, where clopidogrel acts by inhibiting platelet aggregation in the coronary arteries, aspirin acts by blocking the actions of an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets and atorvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol, thus preventing clot or plaque formation in the coronary arteries leading to an uninterrupted supply of oxygen and blood to the heart.

DIRECTIONS FOR USE

Take DEPLATT CV FORTE 75/20/150MG CAPSULE as advised by your physician. Swallow DEPLATT CV FORTE 75/20/150MG CAPSULE with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DEPLATT CV FORTE 75/20/150MG CAPSULE

COMMON

  • increased bleeding or bruising
  • hematoma (collection of blood outside the blood vessel)
  • epistaxis (bleeding from the nose)
  • indigestion, diarrhea, stomach pain, nausea, constipation
  • bleeding in the gut
  • dizziness and headache
  • allergic reaction
  • nasopharyngitis (cold)
  • muscle cramps or pain
  • joint pain, back pain, swelling of joints

UNCOMMON

  • tingling or prickling sensation in hands or feet
  • stomach and duodenal ulcer
  • rash, itching
  • blood in urine
  • loss of appetite, burping
  • weight gain
  • nightmare, difficulty falling asleep
  • blurred vision
  • ringing sensation in ears (tinnitus)
  • loss of sensation, altered taste
  • loss of memory
  • hair loss
  • muscle tiredness, fever
  • neck or chest pain
  • general discomfort, weakness
  • difficulty breathing

RARE

  • vertigo (spinning sensation)
  • breast enlargement in men (gynecomastia)
  • peripheral neuropathy (weakness, numbness and pain from nerve damage, usually in the hands and feet)
  • asthma attacks, bronchospasm
  • intracranial hemorrhage (bleeding in the brain)
  • cholestasis (a liver disease)

Stop taking DEPLATT CV FORTE 75/20/150MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:

  • severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat and neck, difficulty in breathing or swallowing)
  • thrombotic thrombocytopenic purpura (a blood disorder that causes blood clots in capillaries throughout the body)
  • hemorrhagic vasculitis (inflammation of the blood vessels with bleeding)
  • abnormal heavy or prolonged menstrual periods
  • severe skin disorders with fever (Ex. lyell’s syndrome, steven-johnsons syndrome, erythema nodosum, erythema multiforme)
  • rhabdomyolysis (muscle rupture with fever), myositis (inflammation of the muscle) or tendinopathy (painful tendons)

HOW TO MANAGE SIDE EFFECTS

Nausea:

Try to take DEPLATT CV FORTE 75/20/150MG CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if the symptom does not improve.

Diarrhea:

Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom does not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve.

Constipation

Eat fiber rich foods such as fresh fruits, vegetables, cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom does not improve.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in pregnant women. However, consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE. Women of child-bearing potential should use suitable contraceptive method to avoid pregnancy while taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

BREASTFEEDING

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

DRIVING AND USING MACHINES

DEPLATT CV FORTE 75/20/150MG CAPSULE does not impair your ability to drive or operate any machines. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

ALCOHOL

Avoid consumption of alcohol while taking DEPLATT CV FORTE 75/20/150MG CAPSULE as it may increase the risk of stomach bleeding and aggravate your existing condition. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

KIDNEY

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in patients having severe kidney disease and should be used with caution in patients with kidney impairment. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE. 

LIVER

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in patients having severe liver impairment and active liver disease (including persistent elevations of serum transaminases exceeding three times the upper limit) and should be used with caution in patients with liver impairment. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

ALLERGY

Do not take DEPLATT CV FORTE 75/20/150MG CAPSULE if you are allergic to Clopidogrel, Atorvastatin, Aspirin or Prostaglandin synthetase inhibitors (Ex. naproxen, ibuprofen, mefenamic acid and indomethacin).

LUNGS

DEPLATT CV FORTE 75/20/150MG CAPSULE should be used with caution in patients with interstitial lung disease or other respiratory problems such as hay fever, asthma or chronic respiratory diseases due to increased risk of bronchospasm and asthma attacks. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

HEART DISEASE

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in patients with recent ischemic stroke and should be used with caution in patients with high blood pressure. Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

OTHERS

DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use if you:

  • have active or recurrent peptic ulcer with or without gastrointestinal bleeding
  • have bleeding disorders (Ex. bleeding in the brain, hemophilia or others)
  • have thrombocytopenia (decreased platelet count)
  • have gout
  • have menorrhagia (abnormally heavy bleeding during menstruation)

Before taking DEPLATT CV FORTE 75/20/150MG CAPSULE, inform your doctor if you:

  • have an underactive thyroid gland
  • have family history of hereditary muscular disorders
  • have family history of muscle problems following treatment with cholesterol-lowering medicines
  • upcoming planned surgery (including dental surgery)
  • dehydration problem
  • diabetes
  • are alcoholic

Use in pediatrics:

DEPLATT CV FORTE 75/20/150MG CAPSULE is generally not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice.

Use in geriatrics:

DEPLATT CV FORTE 75/20/150MG CAPSULE should be used with caution in elderly patients (aged 70 years and above) because of increased risk of gastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly). Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

INTERACTIONS

A. Drug-Drug interactions:

Before taking DEPLATT CV FORTE 75/20/150MG CAPSULE inform to your doctor, if you are taking any of these medicines:

  • other anticoagulants (used for blood thinning) Ex. warfarin, coumarin, heparin, phenindione
  • other cholesterol-lowering medicines (Ex. clofibrate, gemfibrozil, fenofibrate, ezetimibe, colestipol)
  • other non-steroidal anti-inflammatory drugs (Ex. ibuprofen, indomethacin)
  • medicines used to treat HIV infection (Ex. glecaprevir/pibrentasvir, delavirdine, ritonavir with lopinavir and/or atazanavir or sofosbuvir with velpatasvir and voxilaprevir)
  • st. john's wort (herbal medicine), selective serotonin reuptake inhibitors (used to treat depression) Ex. fluoxetine, sertraline, paroxetine or fluvoxamine 
  • medicines used to treat stomach ulcers such as antacids (Ex. aluminium hydroxide, magnesium hydroxide) and proton-pump inhibitors (Ex. omeprazole or esomeprazole)
  • other medicines used during percutaneous coronary intervention (Ex. abciximab, eptifibatide and tirofiban)
  • antibiotics (used to treat bacterial infections) such as macrolides (Ex. azithromycin, telithromycin, erythromycin, roxithromycin, and clarithromycin) or fusidic acid
  • medicines used to treat epilepsy (Ex. phenytoin, valproic acid, stiripentol)
  • medicines used to treat diabetes (Ex. insulin, glipizide, glimepiride)
  • ciclosporin or tacrolimus (used to prevent graft rejection or treat auto-immune disease)
  • azole antifungal agents (used to treat fungal infection) Ex. clotrimazole, fluconazole
  • methotrexate (used to treat cancer or other auto-immune diseases)
  • lithium (used to treat mental illness)
  • corticosteroids (used to treat pain and inflammation) Ex. prednisolone, dexamethasone
  • acetazolamide (used to treat or prevent altitude sickness)
  • mifepristone (used to prevent pregnancy)
  • metoclopramide (used to treat vomiting)
  • deferasirox (used to treat iron overload)
  • zafirlukst (used to prevent asthmatic symptoms)
  • digoxin, amiodarone and verapamil (used to treat abnormal heart rhythm)
  • angiotensin-converting enzyme (ACE) inhibitors such as captopril, enalapril and diuretics such as hydrochlorothiazide (used to treat high blood pressure)
  • rifampin (used to treat tuberculosis)
  • colchicine, probenecid or sulfinpyrazone (used to treat gout)

B. Drug - Food interaction:

During treatment with DEPLATT CV FORTE 75/20/150MG CAPSULE, do not take more than one or two small glasses of grapefruit juice per day because large quantities of grapefruit juice can alter the effects of this medicine.

Overdosage:

If you or anyone else accidentally take too much of DEPLATT CV FORTE 75/20/150MG CAPSULE, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of DEPLATT CV FORTE 75/20/150MG CAPSULE includes increased bleeding, confusion, disorientation, coma, convulsions, vomiting (sometimes with blood), increased body temperature, low blood sugar levels, tinnitus (ringing in the ears), vertigo (spinning sensation), sweating, warm extremities with bounding pulses, kidney failure, increased respiratory rate and hyperventilation. 

SYNOPSIS

Drug :   Aspirin, Clopidogrel, Atorvastatin
Pharmacological Category :   Antiplatelets, HMG-CoA reductase inhibitors
Therapeutic Indication :   Percutaneous coronary intervention, Myocardial infarction
Dosage Forms :   Tablet, Capsule

MORE INFORMATION

  • Keep DEPLATT CV FORTE 75/20/150MG CAPSULE out of reach of children
  • Store DEPLATT CV FORTE 75/20/150MG CAPSULE at room temperature

FAQs ABOUT DEPLATT CV FORTE 75/20/150MG CAPSULE

Q: Can I try to get pregnant while taking DEPLATT CV FORTE 75/20/150MG CAPSULE?

A: No, DEPLATT CV FORTE 75/20/150MG CAPSULE should be discontinued from use if you are trying to get pregnant because it may cause severe abnormalities to the growing fetus. Also, it is advised that women of child-bearing potential should use suitable contraceptive method to avoid pregnancy while taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

Q: Can I consume alcohol while taking DEPLATT CV FORTE 75/20/150MG CAPSULE?

A: No, avoid consumption of alcohol while taking DEPLATT CV FORTE 75/20/150MG CAPSULE as it could aggravate your existing disease condition and increase the risk of bleeding. Before taking DEPLATT CV FORTE 75/20/150MG CAPSULE inform your doctor if you are alcoholic.  

Q: Can DEPLATT CV FORTE 75/20/150MG CAPSULE cause dizziness?

A: Yes, DEPLATT CV FORTE 75/20/150MG CAPSULE may cause dizziness in some people. To manage this effect, try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve.

Q: What to do if I forget to take DEPLATT CV FORTE 75/20/150MG CAPSULE?

A: You should take DEPLATT CV FORTE 75/20/150MG CAPSULE immediately when you remember. If it is time for your next dose of DEPLATT CV FORTE 75/20/150MG CAPSULE skip the dose and follow your regular dose schedule. Do not double the dose of DEPLATT CV FORTE 75/20/150MG CAPSULE to match up your missed dose.  

Q: Is DEPLATT CV FORTE 75/20/150MG CAPSULE safe to use in patients with liver disease?

A: DEPLATT CV FORTE 75/20/150MG CAPSULE is not recommended for use in patients with severe liver impairment and active liver disease (including persistent elevations of liver enzymes exceeding three times the upper limit) and should be used with caution in patients with liver impairment. Your doctor will regularly monitor your liver function tests during treatment with DEPLATT CV FORTE 75/20/150MG CAPSULE to prevent the risk of liver damage.  

Q: Can DEPLATT CV FORTE 75/20/150MG CAPSULE be used in elderly patients?

A: DEPLATT CV FORTE 75/20/150MG CAPSULE should be used with caution in elderly patients (aged 70 years and above) because of increased risk of gastro-intestinal bleeding and perforation when used for prolonged duration (if prolonged therapy is essential, patients should be reviewed regularly). Consult your doctor before taking DEPLATT CV FORTE 75/20/150MG CAPSULE.

REFERENCES

1. KD. Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis and Hypolipidemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 629-633 & 636-638

2. Jeffery I. Weitz. Blood coagulation and Anticoagulant, Fibrinolytic and Antiplatelet Drugs. Thomas P. Bersot. Drug therapy for hypercholesterolemia and dyslipidemia. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 868-870 & 892-898

3. Ospedale Misericordia e Dolce. Atorvastatin and Clopidogrel High Dose in Stable Patients With Residual High Platelet Activity (ACHIDO). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in January 2012] [Accessed on 7th October 2021] https://clinicaltrials.gov/ct2/show/NCT01335048

4. Hospital do Coracao. Statins Evaluation in Coronary Procedures and Revascularization Trial (SECURE-PCI). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in June 2019] [Accessed on 7th October 2021] https://clinicaltrials.gov/ct2/show/NCT01448642

5. Goeng Bae Kim, Jeong Kyung Kim, Sul Park, Jae Jin Jeong, Hyung Sik Yoon, Sang Hun Ko, Jae Ee Ko, Soo Jin Park, Seon Woo Nam, Jae Hwan Lee and Min Soo Hyon. Effect of Atorvastatin and Clopidogrel Co-Administration After Coronary Stenting in Korean Patients With Stable Angina. NCBI; PMC US National Library of Medicine, National Institute of Health. January 2011. [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040400/

6. Rolf P Kreutz, Jeffrey A Breall Anjan Sinha, Elisabeth von der Lohe, Richard J Kovacs and David A Flockhart. Simultaneous administration of high-dose atorvastatin and clopidogrel does not interfere with platelet inhibition during percutaneous coronary intervention. NCBI; PMC US National Library of Medicine, National Institute of Health. June 2016. [Accessed on 7th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902146/

7. HamidReza Pourhosseini , Reza Lashkari, Arya Aminorroaya, Danesh Soltani, Arash Jalali, Masih Tajdini. Effects of high dose atorvastatin before elective percutaneous coronary intervention on highly sensitive troponin T and one year major cardiovascular events; a randomized clinical trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2019 [Accessed on 7th October 2021] https://pubmed.ncbi.nlm.nih.gov/30671535/

8. Torrent Pharmaceuticals Ltd. Deplatt-CV. Torrentian.com. [Revised in July 2019]. [Accessed on 7th October 2021] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2538.pdf

9. Torrent Pharmaceuticals Ltd. Deplatt-CV 20 Forte (Clopidogrel, Atorvastatin and Aspirin Capsules). Torrentian.com. [Revised in July 2019] [Accessed on 7th October 2021]  https://www.torrentian.com/pisheet/Upload/PI_Sheet/2741.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test
  • Liver function test
  • Complete blood count

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    ASPIRIN 150MG+ATORVASTATIN 20MG+CLOPIDOGREL 75MG
    Hsn Code
    30049099
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