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INTRODUCTION

CYCLOBID SUSPENSION is a combination of Dicyclomine and Paracetamol which belongs to the group of medicines called Antispasmodics and Analgesics, respectively. CYCLOBID SUSPENSION is used in paediatric patients to provide relief from spasmodic pain and discomfort due to biliary colic (abdominal pain), intestinal colic (intestinal pain), renal colic (sharp pain due to kidney dysfunction), and spasmodic dysmenorrhea (sharp pelvic pain at the start of menstrual flow).

CYCLOBID SUSPENSION is also used in paediatric patients to provide relief from the symptoms of irritable bowel syndrome (IBS) and functional bowel disease.

CYCLOBID SUSPENSION is not recommended for use in child allergic to Dicyclomine, and Paracetamol. It is also not recommended for use in children with obstructive uropathy (condition that occurs when urine cannot drain through the urinary tract), intestinal obstruction, severe ulcerative colitis (inflammatory bowel disease), glaucoma (increased eye pressure), and myasthenia gravis (weak and rapid fatigue of muscles).

Before administering CYCLOBID SUSPENSION, inform your doctor if your child has autonomic neuropathy (condition that occurs due to nerve damage to the nerves that control automatic functions of the body), hypertension (high blood pressure), hiatal hernia (condition marked by stomach pushing into the chest cavity), heart disease (such as coronary heart disease, congestive heart failure, cardiac tachyarrhythmia), kidney disease, and/or liver disease.

CYCLOBID SUSPENSION is not recommended for use in pregnant and breastfeeding women as it is intended to be used only in children. It is also not recommended for use in infants (aged less than 6 months) and in elderly patients. Consult your doctor before administering the medicine to the child.

The most common side effects of administering CYCLOBID SUSPENSION in child are hypersensitivity reaction (immune mediated reaction), dry mouth, stomach upset, bloating, flatulence, vomiting, and/or constipation. Consult your doctor if any of these symptoms becomes worse in the child.

USES OF CYCLOBID SUSPENSION

Used in pediatric patients:

  • To provide relief from spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic, spasmodic dysmenorrhea.
  • To provide relief from the symptoms of irritable bowel syndrome (IBS) and functional bowel disease

HOW CYCLOBID SUSPENSION WORKS

CYCLOBID SUSPENSION provides relief from spasmodic pain and discomfort, where Dicyclomine relieves abdominal cramps, pain, bloating and discomfort by relaxing the muscles in the stomach & gut and preventing the occurrence of sudden muscle contractions and Paracetamol provides relief from pain by blocking the action of prostaglandin (chemical messengers responsible for pain) thus providing reducing spasmodic pain and discomfort in affected children.

DIRECTIONS FOR USE

Administer CYCLOBID SUSPENSION in child as directed by your physician. Shake well before use. Your doctor will decide the correct dose and duration for your child depending upon the age, body weight and disease condition.

SIDE EFFECTS OF CYCLOBID SUSPENSION

COMMON

  • signs of hypersensitivity reaction (immune mediated reaction) such as red itchy welts, fever, itching, shortness of breath, wheezing, and/or runny nose
  • dry mouth
  • stomach upset, bloating, flatulence, vomiting, constipation

RARE

Stop administering CYCLOBID SUSPENSION and contact your doctor immediately if your child experience any of the following side effects:

  • signs of heat prostration (overheating of the body due to extreme weather conditions) such as fever, heat stroke

HOW TO MANAGE SIDE EFFECTS

Nausea/vomiting:

Have the child take this medicine just after a meal or a snack. Let the child stick to simple meals and avoid having rich or spicy food.

Constipation:

Ask the child to drink adequate amount of water and include plenty of fruits and vegetables in child’s diet. Constipation should go away after few days followed by its administration in the child. If it persists for longer time or becomes severe then consult your doctor.

Dry mouth:

Ask the child to drink plenty of cold water and sip on cold unsweetened drinks. Brush your child’s teeth twice a day. Consult and inform your doctor if the symptom persists or gets worse.

WARNING & PRECAUTIONS

PREGNANCY

CYCLOBID SUSPENSION is not recommended for use in pregnant women as it is used only in children.

BREASTFEEDING

CYCLOBID SUSPENSION is not recommended for use in breastfeeding women as it is used only in children.

KIDNEY

CYCLOBID SUSPENSION should be used with caution in children with kidney disease. Consult your doctor before administering the medicine to the child.

LIVER

CYCLOBID SUSPENSION should be used with caution in children with liver disease. Consult your doctor before administering the medicine to the child.

ALLERGY

Do not administer CYCLOBID SUSPENSION if the child is allergic to Dicyclomine, Paracetamol, and/or any other ingredients of this medicine.

HEART DISEASE

CYCLOBID SUSPENSION should be used with caution in children with heart diseases such as coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, tachycardia. Consult your doctor before administering the medicine to the child.

OTHERS

CYCLOBID SUSPENSION is not recommended for use in child, if it has:

  • obstructive uropathy (condition that occurs when urine cannot drain through the urinary tract)
  • intestinal obstruction
  • severe ulcerative colitis (inflammatory bowel disease)
  • reflux esophagitis (inflammation of oesophagus)
  • acute bleeding with unstable cardiovascular status
  • glaucoma (increased eye pressure)
  • myasthenia gravis (weak and rapid fatigue of muscles).

Before administering CYCLOBID SUSPENSION, inform your doctor if the child has:

  • autonomic neuropathy (condition that occurs due to damage to the nerves that control automatic functions of the body)
  • hypertension (high blood pressure)
  • hiatal hernia (condition marked by stomach pushing into the chest cavity).

Use in Paediatrics:

CYCLOBID SUSPENSION is not recommended for use in infants (aged less than 6 months). Consult your doctor before administering the medicine to the child.

Use in Geriatrics:

CYCLOBID SUSPENSION is not recommended for use in elderly patients as it is used only in children.

INTERACTIONS

A.Drug - Drug interactions:

Before administering CYCLOBID SUSPENSION, inform your doctor if your child is taking any of the following medicine:

  • amantadine (used to treat Parkinson's disease)
  • antiarrhythmic agents (used to treat and prevent abnormal heartbeats) Ex.  disopyramide, flecainide
  • antihistamines (used to relive symptoms of allergy) Ex. cinnarizine, diphenhydramine
  • antipsychotic agents (medicines used to treat symptoms of psychosis) Ex. risperidone, quetiapine
  • benzodiazepines (used to treat severe anxiety/insomnia) such as alprazolam, chlordiazepoxide
  • MAO inhibitors (used to treat depression) Ex. isocarboxazid, phenelzine
  • narcotic analgesics (used to treat pain) Ex. meperidine
  • nitrates (used to treat angina pectoris) Ex.  nitroglycerin
  • sympathomimetic agents (used to treat cardiac arrest and low blood pressure) Ex. amphetamine, benzylpiperazine 
  • tricyclic antidepressants (used to treat depression) Ex. amitriptyline, amoxapine
  • other anticholinergics (medicines used to treat urinary dysfunction, peptic ulcer, irritable bowel disease) Ex. hyoscyamine
  • metoclopramide (used to stop nausea and vomiting)

Overdosage:

If the child or anyone else accidentally take too much of CYCLOBID SUSPENSION, consult and inform your doctor immediately or visit the nearby hospital. Symptoms of overdose are headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, muscular weakness, and/or convulsion.

SYNOPSIS

Drug :   Dicyclomine, Paracetamol
Pharmacological Category :   Antispasmodics, Analgesics
Therapeutic Indication :   Relief pain & and irritable bowel syndrome (IBS)
Dosage Forms :   Tablet, Suspension, Syrup

MORE INFORMATION

  • Keep CYCLOBID SUSPENSION out of reach of children
  • Do not store CYCLOBID SUSPENSION above 25°C

FAQs ABOUT CYCLOBID SUSPENSION

What is CYCLOBID SUSPENSION used for?

CYCLOBID SUSPENSION is used in paediatric patients to provide relief from spasmodic pain and discomfort due to biliary colic (abdominal pain), intestinal colic (intestinal pain), renal colic (sharp pain due to kidney dysfunction), and spasmodic dysmenorrhea (sharp pelvic pain at the start of menstrual flow). It is also used in paediatric patients to provide relief from the symptoms of irritable bowel syndrome (IBS) and functional bowel disease.

How to take CYCLOBID SUSPENSION?

CYCLOBID SUSPENSION provides relief from spasmodic pain and discomfort, where Dicyclomine relieves abdominal cramps, pain, bloating and discomfort by relaxing the muscles in the stomach & gut and preventing the occurrence of sudden muscle contractions and Paracetamol provides relief from pain by blocking the action of prostaglandin (chemical messengers responsible for pain) thus providing reducing spasmodic pain and discomfort in affected children.

What are the most common side effects of administering CYCLOBID SUSPENSION to a child?

The most common side effects of administering CYCLOBID SUSPENSION in child are hypersensitivity reaction (immune mediated reaction), dry mouth, stomach upset, bloating, flatulence, vomiting, and/or constipation. Consult your doctor if any of these symptoms becomes worse in the child.

What happens to the child if high dose of CYCLOBID SUSPENSION is administered?

If the child or anyone else accidentally take too much of CYCLOBID SUSPENSION, consult and inform your doctor immediately or visit the nearby hospital. Symptoms of overdose are headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, muscular weakness, and/or convulsion.

How CYCLOBID SUSPENSION works?

CYCLOBID SUSPENSION provides relief from spasmodic pain and discomfort, where Dicyclomine relieves abdominal cramps, pain, bloating and discomfort by relaxing the muscles in the stomach & gut and preventing the occurrence of sudden muscle contractions and Paracetamol provides relief from pain by blocking the action of prostaglandin (chemical messengers responsible for pain) thus providing reducing spasmodic pain and discomfort in affected children.

REFERENCES

1. KD. Tripathi. Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia. Essentials of medical pharmacology. Seventh edition. 2013. Page – 117.

2. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 206.

3. Dicyclomine. NIH National Library of Medicine. National center for biotechnology information. PubChem. October 2022. [Accessed on 3rd October 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Dicyclomine#section=Metabolism-Metabolites

4. Marta Józwiak-Bebenista, Jerzy Z Nowak. Paracetamol: mechanism of action, applications and safety concern.  NIH National Library of Medicine. National center for biotechnology information. PubMed.gov. 2014. [Accessed on 3rd October 2022] https://pubmed.ncbi.nlm.nih.gov/24779190/

5. Entera Health, Inc. DailyMed. NIH National Library of Medicine. National center for biotechnology information. [Revised in April 2015] [Accessed on 3rd October 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=f4c97f34-31ce-4459-930a-353e200aad70&type=display

6. Leeford Healthcare Limited. LEEMOL-DC SYRUP. [Accessed on 3rd October 2022] https://www.leeford.in/product/353/leemol-dc-syrup

7. Innovative Pharmaceuticals Pvt Ltd. Cyclobrex Suspension. [Accessed on 3rd October 2022] https://www.innovativepharma.in/product/cyclobrex-suspension/

8. Care Formulation Labs Pvt Ltd. CARESPAS. [Accessed on 3rd October 2022] https://careformulationlabs.com/product/carespas-3/

PRODUCT DETAILS

    Country Of Origin
    India
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ALTERNATE BRANDS
CYCLOBREX Suspension 60ml
Prescription Muscle Spasm Rx required
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CYCLOBID Suspension 60ml

CYCLOBID Suspension 60ml Mkt: Ikon Remedies Pvt Ltd

M.R.P.: Rs.58.95
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