CUFLIFT Expectorant 100ml

INTRODUCTION

CUFLIFT EXPECTORANT is a combination of Ambroxol, Guaiphenesin and Terbutaline which belongs to the group of medicines called Mucolytics, Expectorant and Beta agonists respectively. CUFLIFT EXPECTORANT is used in the relief of cough associated with bronchitis, bronchial asthma, emphysema, and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist (lung and airway diseases that have excessive and thick mucus formation, swelling and inflammation of airways, making it difficult to breath).

Before taking CUFLIFT EXPECTORANT, inform your doctor if you have or have ever had a stomach ulcer, pre-existing ischaemic heart disease or those patients with significant risk factors for ischaemic heart disease, thyrotoxicosis (condition in which you have too much thyroid hormone in your body), diabetes mellitus or hypertension.

CUFLIFT EXPECTORANT should be used with caution in pregnant and breastfeeding women, and elderly patients. CUFLIFT EXPECTORANT is recommended in children to relive symptoms after calculating the correct dose according to their weight and body mass. The common side effects of CUFLIFT EXPECTORANT are tremor (shaky hands), headache, tachycardia (heat beats faster), palpitations (feeling aware of your heartbeat), muscle spasms and hypokalaemia (low plasma potassium levels). Consult your doctor immediately if you feel any of these side effects.

USES OF CUFLIFT EXPECTORANT

• Used to relieve cough associated with bronchitis, bronchial asthma, emphysema, and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist

HOW CUFLIFT EXPECTORANT WORKS

CUFLIFT EXPECTORANT is a combination of Ambroxol, Guaiphenesin and Terbutaline. Ambroxol thins and loosens mucus making it easier to cough out. Guaiphenesin belongs to expectorant which decreases the stickiness of mucus and helps in its removal from the airways. Terbutaline works by relaxing the muscles in the airways and widens the airways.

DIRECTIONS FOR USE

Take CUFLIFT EXPECTORANT as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF CUFLIFT EXPECTORANT

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Nausea And Vomiting

Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

There are no adequate and well-controlled studies of CUFLIFT EXPECTORANT in pregnant women. It should be administered with caution in pregnancy. Consult your doctor for advice.

BREASTFEEDING

Use with Caution

CUFLIFT EXPECTORANT should be used with caution during breastfeeding. Consult your doctor for advice.

DRIVING AND USING MACHINES

Use with Caution

CUFLIFT EXPECTORANT does not influence the capacity of driving or operating any machines. Consult your doctor for advice.

KIDNEY

Use with Caution

CUFLIFT EXPECTORANT should be used with caution in patients with kidney diseases. Consult your doctor for advice.

LIVER

Use with Caution

CUFLIFT EXPECTORANT should be used with caution in patients with liver diseases. Consult your doctor for advice.

ALLERGY

Contraindicated

Do not take CUFLIFT EXPECTORANT if you are allergic to Ambroxol, Guaiphenesin, Terbutaline or any other ingredients of this medicine.

HEART DISEASE

Use with Caution

CUFLIFT EXPECTORANT should be used with caution in patients with heart diseases. Consult your doctor for advice.

USE IN PEDIATRICS

Consult your doctor

Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor for advice before taking CUFLIFT EXPECTORANT.

USE IN GERIATRICS

Use with Caution

CUFLIFT EXPECTORANT should be used with caution in elderly patients. Consult your doctor for advice.

INTERACTIONS

A. Drug-Drug interactions:

Before taking CUFLIFT EXPECTORANT, inform your doctor if you are taking any of the following medicine:

• medicines used to treat high blood pressure (Ex. propranolol)
• diuretics (Ex. spironolactone)
• monoamine oxidase inhibitors used to treat depression (Ex. isocarboxazid)
• methyl xanthine to treat lung disorders (Ex. aminophylline)
• corticosteroids used to treat severe infections (Ex. deflazacort)
• antibiotics used to treat infections. (Ex. as ampicillin, amoxicillin, erythromycin)

Overdosage:

If you or anyone else accidentally takes too much of CUFLIFT EXPECTORANT, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are abdominal pain, agitation, palpitations (being of your heartbeat), seizures/fits, hypertension, hypotension (fainting) tachycardia (increased heartbeat) nervousness, headache, tremor, dry mouth, nausea, vomiting, dizziness, fatigue, malaise (weakness) insomnia (sleeplessness).

SYNOPSIS

MORE INFORMATION

• Keep CUFLIFT EXPECTORANT out of reach of children
• Store at room temperature

FAQs ABOUT CUFLIFT EXPECTORANT

Q: What is CUFLIFT EXPECTORANT used for?

A: CUFLIFT EXPECTORANT is used in the relief of cough associated with bronchitis, bronchial asthma, emphysema, and other bronchopulmonary disorders where bronchospasm, mucous plugging and problems of expectoration co-exist (lung and airway diseases that have mucus, swelling, inflammation making it difficult to breath).

Q: How is CUFLIFT EXPECTORANT useful in treating severe cough?

A: CUFLIFT EXPECTORANT is a combination of Ambroxol, Guaiphenesin and Terbutaline.  Ambroxol improves the mucus transport by breaking down acid mucopolysaccharide fibres and makes the sputum thinner and less viscous and therefore more easily removed. Guaiphenesin increases respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Terbutaline predominantly stimulates beta 2-receptors (these a kind of receptors present in airway smooth muscles) thus producing relaxation of bronchial smooth muscle. When the medicine is given in combination, it makes breathing easier and relives the discomfort.

Q: How to use CUFLIFT EXPECTORANT?

A: Take CUFLIFT EXPECTORANT as advised by your physician. Shake well before use. May be taken with or without food. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: What are the common side effects seen with CUFLIFT EXPECTORANT?

A: CUFLIFT EXPECTORANT also has few side effects like tremor, feeling sick (nausea) or being sick (vomiting), pain in the upper part of your abdomen, diarrhoea, elevation in liver enzymes, nervousness, dizziness and drowsiness, headache, anxiety, palpitation, rapid heart rate, shortness of breath, chest discomfort, weakness. Consult your doctor if you experience these side effects.

Q: Will CUFLIFT EXPECTORANT be more effective if taken in more than recommended doses?

A: No, taking a higher than the recommended dose may not be more effective, rather it may   increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, consult your doctor for advice.

REFERENCES

1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Chapter 16 Essentials of medical pharmacology. Seventh edition. 2017.

2. K. Lakshmi Narasimha Rao, Ch. Krishnaiah, K. Sudheer Babu, K. Padmaja Reddy. Development and validation of a stability-indicating LC method for simultaneous determination of related compounds of guaifenesin, terbutaline sulphate and Ambroxol HCl in cough syrup formulation. Jan 2012. [Accessed on 25th June 2022] https://www.sciencedirect.com/science/article/pii/S1319610312000099

3. Cipla med. Ambroxol + Guaiphenesin +Terbutaline. [Revised in Nov 2013] [Accessed on  July 2022] https://www.ciplamed.com/content/cheston-plus-syrup

4. Cipla med. Ambroxol + Guaiphenesin +Terbutaline. [Revised in Aug 2015] [Accessed on July 2022] https://www.ciplamed.com/content/axalin-expectorant

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 14 Feb 2023 | 10:36 AM(IST)