INTRODUCTION

COXET 90MG contains Etoricoxib which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It helps in reducing pain and swelling in the joints and muscles of people aged 16 years and older with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout. It is also used as a short-term treatment of moderate pain after dental surgery in people 16 years of age and older.

Arthritis is a condition resulting from gradual breakdown of cartilage that cushions ends of the bones resulting in swelling, pain, tenderness and stiffness of joints. Inflammatory disease of spine and large joints is termed as ankylosing spondylitis. Gout is a condition characterized by sudden, recurring attacks of painful inflammation and redness in joints due to deposition of mineral crystals in the joint.

Always take this medicine exactly as doctor has told you. It can be taken with or without food. COXET 90MG is not recommended for use in children and adolescents under 16 years of age. Do not drive or use tools or machines if you experience dizziness or sleepiness. The most common side effects are stomach pain, swelling of legs and/or feet due to the fluid retention, dizziness, headache, palpitations, irregular heartbeat, increased blood pressure, wheezing or shortness of breath (bronchospasms), constipation, gastritis, heartburn, diarrhea, indigestion, nausea and vomiting.

USES OF COXET 90MG

• reduce pain and swelling in the joints
• treat moderate pain after dental surgery in people 16 years of age and older

HOW COXET 90MG WORKS

COXET 90MG works by blocking the action of a substance in body called cyclo-oxygenase. Cyclo-oxygenase in response to injury or diseases produce prostaglandins which cause the pain, swelling and inflammation. This inhibition results analgesics and anti-inflammatory action.

DIRECTIONS FOR USE

Always take this medicine exactly as doctor has told you. It can be taken with or without food.

SIDE EFFECTS OF COXET 90MG

HOW TO MANAGE SIDE EFFECTS

Skin itching:

Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking:

• anticoagulants such as warfarin
• rifampicin (an antibiotic)
• methotrexate (treat rheumatoid arthritis)
• ciclosporin or tacrolimus (immunosuppressant)
• lithium (used to treat depression)
• medicines used to help control high blood pressure and heart failure
• salbutamol (a medicine for asthma)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT COXET 90MG

Can COXET 90MG be used in pregnant women?

No. It is not recommended for use in the pregnant women. Consult your doctor before taking this medicine.

How quickly does COXET 90MG work?

The onset of pain relief was rapid, with similar benefit reported within 4 hours of the first dose of this medicine.

How COXET 90MG works?

It helps to reduce the pain and swelling (inflammation) in the joints and muscles of people 16 years of age and older with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

REFERENCES

1. Peter Brooks and Paul Kubler; Etoricoxib for arthritis and pain management, [Published on 2006] [Accessed 11 Nov 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661646/

2. K.D.Tripathi, Essentials of medical pharmacology, NSAIDs and antipyretic-analgesics, Chapter 14  – Autacoids and related drugs, Page - 192, 205, 206, 213.

3. Zentiva Pharma UK Limited; Electronic Medicines Compendium (EMC); [Revised on 02/2020] [Accessed 11 Nov 2020] https://www.medicines.org.uk/emc/files/pil.668.pdf

4. Salutas Pharma GmbH, Otto-von-Guericke-Allee 1, 39179 Barleben, Germany; Electronic Medicines Compendium (EMC); [Revised on 12/2016] [Accessed 11 Nov 2020] https://www.hpra.ie/img/uploaded/swedocuments/2182549.PA0711_232_004.ea52bce2-53d4-4ed2-b4e5-37c0522f0cee.000001PIL.170110.pdf