CORTENT N Cream 20gm

INTRODUCTION

CORTENT N CREAM is a combination of Clobetasol and Neomycin which belongs to the group of medicines called Corticosteroids and Antibiotics. It is used to treat resistant dermatoses (skin infections) with secondary fungal infections. Ex. psoriasis (except widespread plaque psoriasis) and recalcitrant dermatoses.

CORTENT N CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, pruritus without inflammation, perianal and genital pruritus, and perforated ear drum. Contact your doctor before applying.

CORTENT N CREAM should be used with caution in patients with kidney disease, psoriasis. Contact your doctor before applying.

CORTENT N CREAM is generally not recommended for use in pregnancy. Contact your doctor before applying. CORTENT N CREAM is generally not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

CORTENT N CREAM is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.

CORTENT N CREAM should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before applying.

The most common side effects of this medicine are pruritus, skin burning or skin pain. Contact your physician if any of the symptoms worsen.

USES OF CORTENT N CREAM

It is used to treat:

• resistant dermatoses (skin infections) with secondary fungal infection Ex. psoriasis (except widespread plaque psoriasis)
• recalcitrant dermatoses

HOW CORTENT N CREAM WORKS

CORTENT N CREAM helps to treat infection, where Clobetasol belongs to corticosteroids which blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Neomycin is an antibiotic which stops the growth of bacteria in the skin. Together, treats skin infection effectively.

DIRECTIONS FOR USE

Apply CORTENT N CREAM as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes.

SIDE EFFECTS OF CORTENT N CREAM

WARNING & PRECAUTIONS

PREGNANCY

Contraindicated

CORTENT N CREAM is not recommended for use in pregnancy. Contact your doctor before applying.

BREASTFEEDING

Contraindicated

CORTENT N CREAM is not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

KIDNEY

Use with Caution

CORTENT N CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.

ALLERGY

Contraindicated

Do not use CORTENT N CREAM if you are allergic to Clobetasol or Neomycin or to any other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug interactions:

Tell your doctor before using CORTENT N CREAM if you are taking the following medicines:

• ritonavir (medicines used for HIV infections)
• itraconazole (medicines used for fungal infections)
• aminoglycosides like amikacin, gentamicin (medicines used for bacterial infections)
• neuromuscular blocking agents like atracurium, pancuronium (medicines used in anaesthesia)

Overdosage:

If you or anyone else accidentally uses too much of CORTENT N CREAM, consult your doctor immediately or visit the nearby hospital. Acute overdosage is very unlikely, however, in the case of chronic overdosage or misuse, hypercortisolism-like symptoms may occur.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store CORTENT N CREAM below 25°C

FAQs ABOUT CORTENT N CREAM

Q: What are the possible side effects of applying CORTENT N CREAM?

A: The most common side effects of this medicine are pruritis, skin burning sensation or skin pain. Contact your physician if any of the symptoms worsen.

Q: How CORTENT N CREAM works?

A: CORTENT N CREAM helps to treat infection where Clobetasol is a corticosteroid which blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Neomycin is an antibiotic which stops the growth of bacteria in the skin. Together, treats skin infection effectively.

Q: For what conditions CORTENT N CREAM is used?

A: CORTENT N CREAM is used to treat resistant dermatoses (skin infections) with secondary fungal infections, Ex. psoriasis (except widespread plaque psoriasis) and recalcitrant dermatoses. Contact your doctor before applying.

Q: Can I stop using CORTENT N CREAM when my symptoms are relieved?

A: No, do not stop using CORTENT N CREAM and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Q: How long do the effects of this CORTENT N CREAM last?

A: The amount of time for which CORTENT N CREAM remains active in your body is not clinically established.

Q: Who should not apply CORTENT N CREAM?

A: CORTENT N CREAM is not recommended for use in patients with pregnancy, breast feeding women, children under 2 years of age, rosacea, acne vulgaris, perioral dermatitis, pruritus without inflammation, perianal and genital pruritus, and perforated ear drum. Contact your doctor before applying.

REFERENCES

1. K.D. Tripathi. Corticosteroids, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 289, 792, 750.

2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051

3. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin

4. GlaxoSmithKline Pharmaceuticals Limited. Clobetasol propionate and neomycin. [Revised in July 2020] [Accessed on 24th June 2022] https://india-pharma.gsk.com/media/6415/tenovate-gn.pdf

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 25 Jan 2023 | 07:04 PM(IST)