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Drug Information

What is Tamsulosin + Dutasteride combination used for?

Tamsulosin + Dutasteride combination is used for the treatment of enlarged prostate gland (benign prostatic hyperplasia-BPH).

Tamsulosin + Dutasteride combination may also be prescribed for other conditions as determined by the doctor.

How does Tamsulosin + Dutasteride combination work?

In Tamsulosin + Dutasteride combination, Tamsulosin belongs to the class of drugs called alpha blockers. It works by relaxing the muscles of the bladder and prostate gland. Thus, it helps in relieving the symptoms of BPH, such as difficulty in urination, urge to urinate and decreased urine volume.

Dutasteride belongs to the class of drugs called 5-alpha-reductase inhibitors. It works by blocking the enzyme that is responsible for the conversion of testosterone, which helps in the growth of the prostate gland. Inhibition of the enzyme helps in reducing the size of the gland and relieving the symptoms, such as difficulty urinating or urinary urgency.

How to take Tamsulosin + Dutasteride combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Tamsulosin + Dutasteride combination as prescribed by your doctor.

Swallow the capsule whole. Do not crush or chew the capsule. Take Tamsulosin + Dutasteride combination with or without food.

If you miss a dose of Tamsulosin + Dutasteride combination, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Tamsulosin + Dutasteride combination?

Drugs that interact with Tamsulosin + Dutasteride combination are:

  • Acetaminophen
  • Aspirin
  • Cholecalciferol
  • Clopidogrel
  • Cyanocobalamin
  • Esomeprazole
  • Furosemide
  • Levodopa
  • Metoprolol
  • Pregabalin
  • Rivaroxaban
  • Rosuvastatin
  • Tadalafil

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Tamsulosin + Dutasteride combination?

The following are the most common side effects of Tamsulosin + Dutasteride combination:

  • Nausea
  • Vomiting
  • Dizziness
  • Drowsiness
  • Inflammation
  • Itching
  • Fever
  • Shortness of breath

The following are the severe side effects, and you may require immediate medical attention:

  • Swelling of the face, throat and tongue
  • Trouble breathing
  • Allergic skin reactions
  • Decreased semen volume
  • Painful or difficult urination

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Tamsulosin + Dutasteride combination?

  • Seek doctor’s advice before taking any other drug or herbal products while on Tamsulosin + Dutasteride
  • Avoid Tamsulosin + Dutasteride combination during pregnancy or breastfeeding because the safe use of the drug is not yet established.
  • Do not consume alcohol while using Tamsulosin + Dutasteride combination as it may cause dizziness or blurred vision.
  • Avoid grapefruit and grape juice while on Tamsulosin + Dutasteride
  • Avoid Tamsulosin + Dutasteride combination in case of allergic reactions.
  • Keep the medication out of reach of children.

You are advised not to take Tamsulosin + Dutasteride combination if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Tamsulosin + Dutasteride combination?

  • Inform your doctor if you have any pre-existing liver or kidney diseases, bleeding problems etc.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform the doctor if you have any hypersensitivity to any of the drugs in Tamsulosin + Dutasteride

Frequently asked questions about Tamsulosin + Dutasteride combination

  1. Is it safe to use Tamsulosin + Dutasteride combination before undergoing cataract surgery?
  2. No, it is not advisable to use Tamsulosin + Dutasteride combination before undergoing a cataract surgery as it may increase the risk of side effects. Please inform the doctor about the usage of the drug before surgery.  

  3. Is it safe to plan for pregnancy while on Tamsulosin + Dutasteride combination?
  4. No, do not plan your pregnancy while using Tamsulosin + Dutasteride combination, as it may cause birth defects. However, please consult your doctor.

  5. Can I discontinue taking Tamsulosin + Dutasteride combination when I feel better?
  6. Do not stop taking Tamsulosin + Dutasteride combination abruptly unless instructed by the doctor. Discontinuing the medication suddenly may cause the illness to return.

  7. Can I recommend Tamsulosin + Dutasteride combination to a geriatric patient?
  8. No, it is not advisable to recommend Tamsulosin + Dutasteride combination to geriatric patients. Older adults may be sensitive to the side effects of the drug, such as low blood pressure and dizziness. Therefore, this may increase the risk of falling.

  9. Can I take Terazosin while using Tamsulosin + Dutasteride combination?
  10. It is not advisable to take Terazosin while on Tamsulosin + Dutasteride combination. Taking these drugs together may cause a decrease in the blood pressure. However, consult your doctor before taking the drug.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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