Confinex 1mg Tablet 10'S

Constipation Rx required
NOT AVAILABLE

Best Price*  ₹ 132.00
MRP ₹165.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mfr: Abbott Healthcare Pvt Ltd * Country of Origin: NA



INTRODUCTION

CONFINEX 1MG contains prucalopride which belongs to the group of medicines called prokinetic agents. It is used in the treatment of chronic idiopathic constipation in adults, in whom laxatives do not work well enough. Chronic idiopathic constipation is a condition characterized by infrequent bowel movements or difficulty in passage of stools for a longer period without a known cause.

Prucalopride acts on the muscle wall of the gastrointestinal tract and restores the normal functioning of the bowel. Along with this treatment, eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Try to keep yourself more active by exercising regularly. The most common side effect of taking this medicine are headache, feeling sick, diarrhea and abdominal pain. These side effects mostly occur at the starting of therapy and usually disappear within a few days with treatment.

Always take CONFINEX 1MG as directed by your physician. It can be taken with or without food and drinks and at any time of the day. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Before taking this medicine, inform your doctor if you have obstruction or perforation of gut wall or severe inflammation of intestinal tract. This medicine is only meant for use in adults and should not be taken by children and adolescents up to 18 years. It is not recommended for use in pregnant and lactating women. Consult your doctor before taking this medicine.

USES OF CONFINEX 1MG

  • Chronic idiopathic constipation

HOW CONFINEX 1MG WORKS

Prucalopride is a selective stimulator of serotonin 5HT4-receptors, which is found throughout the gastrointestinal tract. Activation of serotonin 5HT4-receptors results in the release of acetylcholine which is the major excitatory neurotransmitter in the GI tract. This results in increased GI-motility. Additionally, prucalopride causes contraction of the muscle layer around the colon and relaxation of the circular muscle layer leading to the propulsion of luminal content.

DIRECTIONS FOR USE

Always use this medicine as directed by your physician. It can be taken with or without food and drinks and at any time of the day. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF CONFINEX 1MG

COMMON

  • headache
  • feeling sick (nausea) or being sick (vomiting)
  • diarrhea and stomach pain
  • decreased appetite
  • dizziness
  • disturbed digestion (dyspepsia)
  • bloating
  • tiredness

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with or just after a meal or a snack. Stick to simple meals. Do not eat rich or spicy food.

Bloating or wind:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.

Diarrhea:

Drink lots of fluids, like water or squash, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Headache:  

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Decreased appetite:

Eat when you expect to be hungry. Eat smaller meals more often than usual. Snack when you're hungry. Have nutritious snacks rich in calories and protein, such as dried fruit and nuts.

WARNING & PRECAUTIONS

PREGNANCY

CONFINEX 1MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

CONFINEX 1MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

KIDNEY

CONFINEX 1MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

CONFINEX 1MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic (hypersensitive) to prucalopride.

LUNGS

CONFINEX 1MG should be taken with caution in patients with severe lung disease. Consult your doctor for advice.

HEART DISEASE

CONFINEX 1MG should be taken with caution in patients with severe heart disease. Consult your doctor for advice.

OTHERS

Before taking this medicine, inform your doctor, if you:

  • have any serious nervous system or mental health problems, cancer, AIDS or a hormonal disorder
  • suffer from obstruction or perforation of gut wall, severe inflammation of intestinal tract, such as crohn’s disease, ulcerative colitis or toxic megacolon/megarectum

INTERACTIONS

Tell your doctor about all the medicines you use, including prescription and non-prescription medicines, and herbal supplements.

SYNOPSIS

Drug :   Prucalopride
Pharmacological Category :   Prokinetic agent, Selective serotonin 5HT4 agonist
Therapeutic Indication :   Chronic idiopathic constipation
Dosage Forms :   Tablet

MORE INFORMATION

Store at room temperature and keep out of reach of children.

FAQs ABOUT CONFINEX 1MG

Can CONFINEX 1MG be used during pregnancy?

No. This medicine is strictly not recommended for use during pregnancy. Consult your doctor before taking.

Can CONFINEX 1MG be taken with juice?

Yes. This medicine can be taken with food and drinks and at any time of the day.

Can CONFINEX 1MG cause dizziness?

Yes. This medicine may cause dizziness in some individuals, although not everybody gets them. Avoid travelling, driving or operate machines if you feel dizzy.

REFERENCES

1. KD. Tripathi. Drugs for Constipation and Diarrhea. Essentials of medical pharmacology. Seventh edition. 2013. Page – 675.

2. Keith A. Sharkey and John L. Wallace. Treatment of disorders of bowel motility and water flux; Antiemetics; Agents used in biliary and pancreatic disease. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1327.

3. Kenneth R. McQuaid. Drugs Used in the Treatment of Gastrointestinal Diseases. Basic and Clinical Pharmacology. 14th Edition. New York McGarw Hill Education 2018.  Page – 1100.

4. Movetis. Efficacy and Safety Study of Prucalopride to Treat Chronic Constipation. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2013] [Accessed 25th November 2020] https://clinicaltrials.gov/ct2/show/NCT00488137

5. Michael Camilleri, Hubert Piessevaux, Yan Yiannakou, Jan Tack, René Kerstens, Eamonn M. M. Quigley, MeiYun Ke, Susana Da Silva, and Amy Levine. Efficacy and Safety of Prucalopride in Chronic Constipation: An Integrated Analysis of Six Randomized, Controlled Clinical Trials. NCBI; PMC US National Library of Medicine, National Institute of Health. April 2016. [Accessed 25th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943977/

6. Anam Omer and Eamonn M.M. Quigley. An update on prucalopride in the treatment of chronic constipation. NCBI; PMC US National Library of Medicine, National Institute of Health. November 2017. [Accessed 25th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673021/

7. Sanico NV & Janssen Cilag S.P.A. Electronic Medicines Compendium (EMC); [Revised on June 2020] [Accessed 25th November 2020] https://www.medicines.org.uk/emc/files/pil.586.pdf

Manufacturer/Marketer Details

    Net Qty
    1
    Shelf Life
    NA
    Item Weight
    17.5
    No. of Units in a Kit
    NA
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