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Comtrix CV Tablet 10'S
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INTRODUCTION
COMTRIX CV TABLET is a combination of Cefixime and Clavulanic Acid which belongs to the group of medicines called Antibiotics. It is used to treat bacterial infections of the ear, nose, throat, respiratory tract (bronchus, lungs), urinary tract and genital tract. It can also be used in the treatment of typhoid fever.
A bacterial infection can be defined as a proliferation of various harmful strains of bacteria within the body. They can affect any part(s) of the body including the respiratory tract, urinary tract, reproductive tract, eyes, ears, skin, soft tissue or bones.
Take COMTRIX CV TABLET for the stipulated duration as instructed by the doctor to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control.
COMTRIX CV TABLET is suitable for use both in adults and in children aged 10 years or older. Before taking COMTRIX CV TABLET inform your doctor if you have any stomach problems or kidney problems. You must also inform your doctor if you are pregnant or breastfeeding before taking COMTRIX CV TABLET as a precaution.
The most common side effects of taking COMTRIX CV TABLET are nausea, vomiting, diarrhea, stomach pain and bloating. Inform your doctor if they trouble you.
USES OF COMTRIX CV TABLET
It is used in adults and in children (aged 10 years or above) to treat bacterial infections such as:
- Ear infections (Ex. otitis media)
- Throat infections (such as tonsillitis and pharyngitis)
- Respiratory tract infections (such as bronchitis and pneumonia)
- Urinary tract infections (such as cystitis, cystourethritis, pyelonephritis)
- Genital tract infections (such as gonorrhoea)
- Typhoid fever
HOW COMTRIX CV TABLET WORKS
COMTRIX CV TABLET is a powerful antibiotic. It contains two medicines namely, cefixime and clavulanic acid. Cefixime kills the susceptible bacteria by blocking the bacterial cell wall synthesis.
Clavulanic acid stops the bacteria from producing toxic proteins (such as beta lactamases) that can reduce the effects of antibiotics. Collectively, these actions destroy the susceptible bacteria, prevent their further growth and multiplication which in turn reduces the severity of the infection.
DIRECTIONS FOR USE
Take COMTRIX CV TABLET as advised by your physician. It can be taken with or without food.
For Tablets: Swallow the medicine with a glass of water. Do not crush or chew the medicine
For Dispersible Tablet: Disperse the medicine in required quantity of water before consumption. Consume the dispersed medicine immediately after dissolution. Do not swallow the medicine as a whole or crush or chew it.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not skip doses or stop taking COMTRIX CV TABLET without consulting your doctor as it may increase the severity of the infection.
SIDE EFFECTS OF COMTRIX CV TABLET
COMMON
- nausea, vomiting
- stomach pain, indigestion, flatulence
- headaches
- dizziness
- itching in genitals or vaginal area
RARE
Stop taking COMTRIX CV TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
- severe skin reactions (such as widespread skin rash, blistering, peeling or bleeding on any part of the skin with fever, chills, enlarged lymph nodes and malaise or pink or reddish skin lesions on palms or soles)
- unusual bleeding or bruising, bleeding from the nose or gums with pale skin, tiredness, chills and shortness of breath
- fever or flu-like symptoms
- bloody urine or difficulties in urination
- signs of brain damage (such as fits with or without confusion, lack of alertness and unusual muscle movements)
- signs of stomach damage causing severe uncontrollable watery diarrhoea along with fever and weakness
HOW TO MANAGE SIDE EFFECTS
Nausea or vomiting:
Take COMTRIX CV TABLET with, or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Please consult your doctor immediately if you experience severe nausea and vomiting.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
WARNING & PRECAUTIONS
PREGNANCY
COMTRIX CV TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor for advice before taking it.
BREASTFEEDING
COMTRIX CV TABLET should be used with caution among breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machines if your ability is affected by COMTRIX CV TABLET.
ALCOHOL
Avoid consumption of alcohol while taking COMTRIX CV TABLET as it might make you feel dizzier.
KIDNEY
COMTRIX CV TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take COMTRIX CV TABLET if you are allergic to Cefixime or Clavulanic acid.
OTHERS
Before taking COMTRIX CV TABLET, inform your doctor if you:
- have ever had colitis (inflammation of the colon)
- are going to have any blood or urine test in the upcoming days
Use in paediatrics:
COMTRIX CV TABLET can be used in children and adolescents aged 10 years or older if prescribed by the physician. However, consult your doctor for advice.
Use in geriatrics:
COMTRIX CV TABLET should be used with caution in the elderly patients. Therefore, consult your doctor for advice before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking COMTRIX CV TABLET, inform your doctor if you are taking any of the following medicines such as:
- warfarin (a medicine used for blood thinning)
- carbamazepine (a medicine used for epilepsy)
Overdosage:
If you or anyone else accidentally took more COMTRIX CV TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Cefixime, Clavulanic acid |
| Pharmacological Category | : | Cephalosporins, Beta-Lactamase Inhibitors |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Dispersible Tablet, Cap tab, Dry syrup,Oral solution, Oral suspension |
MORE INFORMATION
- Keep COMTRIX CV TABLET out of reach of children
- Store COMTRIX CV TABLET at room temperature
FAQs ABOUT COMTRIX CV TABLET
What is the use of COMTRIX CV TABLET?
COMTRIX CV TABLET is used to treat bacterial infections of the ear, nose, throat, respiratory tract (bronchus, lungs), urinary tract and genital tract. It can also be used in the treatment of typhoid fever.
How COMTRIX CV TABLET works in my body?
COMTRIX CV TABLET is a powerful antibiotic with bacteriostatic properties. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis. It can also remain unaffected by the toxic proteins produced by the bacteria (such as beta lactamases). Collectively, these actions destroy the susceptible bacteria, prevent their further growth and multiplication and reduce the severity of the infection.
Can COMTRIX CV TABLET be used in patients with kidney problems?
COMTRIX CV TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
How should I take COMTRIX CV TABLET?
Take COMTRIX CV TABLET as advised by your physician. It can be taken with or without food. For Tablets, swallow the medicine with a glass of water. Do not crush or chew the medicine. For dispersible tablets, disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.
For how long should I take COMTRIX CV TABLET?
Take COMTRIX CV TABLET for the stipulated duration as prescribed by your doctor. Do not skip the medicine or stop taking it on your own as it can cause the infection to reappear.
Can COMTRIX CV TABLET be given to pregnant women?
COMTRIX CV TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor for advice before taking it.
What precautions should I follow while taking COMTRIX CV TABLET?
Before taking COMTRIX CV TABLET inform your doctor if you have stomach or kidney problems. You must also inform your doctor if you are pregnant or breastfeeding. Regularly visit your doctor for check-up and perform all medical tests recommended by your doctor without fail. Take COMTRIX CV TABLET for the stipulated duration recommended by your doctor to achieve better results. Failing to do so may cause the symptom to re-occur.
What are the common side effects of taking COMTRIX CV TABLET?
The most common side effects of taking COMTRIX CV TABLET are nausea, vomiting, diarrhea, stomach pain and bloating. Inform your doctor if they trouble you.
Can I stop taking COMTRIX CV TABLET once my symptoms subside?
Do not stop taking COMTRIX CV TABLET once your symptoms subside. It is important to take the full course of COMTRIX CV TABLET to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control. It may also cause your symptoms to reappear.
Can the use of COMTRIX CV TABLET cause diarrhea?
COMTRIX CV TABLET may cause diarrhea in some individuals. If you experience diarrhea, drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens contact your doctor immediately.
What should I do if I forgot to take a dose of COMTRIX CV TABLET?
If you forgot to take a dose of COMTRIX CV TABLET, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose to compensate the forgotten dose.
REFERENCES
1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. 7th Edition, 2013. Page – 728, 724.
2. Ketan Pakhale, G K Tandon, Tanmay Bansal, Vineet Jain, Dhiraj Dhoot, Saiprasad Patil, Hanmant Barkate. The efficacy and safety of short course therapy with Cefixime in URTI in Indian Scenario. IP Journal of Otorhinolaryngology and Allied Science. [Accessed on 24th November 2022] https://www.joas.co.in/html-article/12482
3. Sanofi. Electronic Medicines Compendium (EMC). [Revised in April 2021]. [Accessed on 24th November 2022] https://www.medicines.org.uk/emc/files/pil.5534.pdf
4. Torrent Pharmaceuticals Ltd [Revised in August 2019] [Accessed on 24th November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1725.pdf
5. Cipla Ltd. Omnix CV Tablets (Cefixime+Clavulanic Acid). [Revised on July 2022]. [Accessed on 24th November 2022] https://www.ciplamed.com/content/omnix-cv-tablets-0
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear Examination
- Kidney Function Test
PRODUCT DETAILS
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