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Drug Information for COMEDOLYTIC Cream 20gm

What is COMEDOLYTIC Cream used for?

COMEDOLYTIC Cream capsule is used for the treatment of acute promyelocytic leukaemia.

COMEDOLYTIC Cream cream/gel is used for the treatment of acne, fine lines, wrinkles and other skin diseases.

COMEDOLYTIC Cream may also be prescribed for other conditions as determined by the doctor.

How does COMEDOLYTIC Cream work?

COMEDOLYTIC Cream belongs to the class of drugs called retinoids. COMEDOLYTIC Cream capsule works by promoting the growth and maturation of blood cells in the bone marrow. Thus, it helps in reducing the symptoms of the condition.

COMEDOLYTIC Cream cream/gel works by decreasing the adherence of follicular epithelial cells, which decreases the formation of blackheads. It also stimulates the mitotic activity, which helps in the growth of follicular epithelial cells. Thus, it causes extrusion of the blackheads.     

How to use COMEDOLYTIC Cream?

The dosage and the drug form depend on the age, weight and medical condition of an individual.

  • Swallow the capsule whole. Do not crush or chew the capsule. Take COMEDOLYTIC Cream with or without food.
  • Apply a thin layer of cream/gel on the affected area and rub it gently.

If you miss a dose of COMEDOLYTIC Cream, please use it once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

The overdose symptoms of COMEDOLYTIC Cream topical may include:

  • Excessive redness
  • Peeling of the skin
  • Discomfort

You must seek immediate medical care if you experience any of the above symptoms.

What are the drugs that interact with COMEDOLYTIC Cream?

The drugs that interact with COMEDOLYTIC Cream capsule are:

  • Albuterol
  • Aripiprazole
  • Cetirizine
  • Cholecalciferol
  • Clonazepam
  • Cyanocobalamin
  • Diphenhydramine
  • Duloxetine
  • Escitalopram
  • Lamotrigine
  • Montelukast
  • Pregabalin
  • Sertraline

The drug that interacts with COMEDOLYTIC Cream topical is:

  • Clindamycin Topical
  • Methoxsalen
  • Resorcinol Topical
  • Sulphur Topical
  • Verteporfin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of COMEDOLYTIC Cream?

The following are the most common side effects of COMEDOLYTIC Cream capsule :

  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Dry mouth
  • Drowsiness
  • Weakness
  • Mouth ulcers
  • Profuse sweating

The following are the most common side effects of COMEDOLYTIC Cream topical :

  • Allergy
  • Itching
  • Dry skin
  • Rash
  • Inflammation
  • Redness

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions COMEDOLYTIC Cream?

  • Seek doctor’s advice before taking any other drug or herbal products while on COMEDOLYTIC Cream
  • Do not exceed the dose more than what is prescribed.
  • Do not drive or operate heavy machinery if COMEDOLYTIC Cream capsule causes dizziness or blurred vision.
  • Inform your doctor if you have rapid swelling of lips, throat and tongue.
  • Do not stop using the medication abruptly unless instructed by the doctor. Suddenly stopping the medication may cause the illness to return.

You are advised not to use COMEDOLYTIC Cream if:

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before using COMEDOLYTIC Cream?

  • Tell your doctor if you are allergic to COMEDOLYTIC Cream or similar drugs.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform your doctor if you have any pre-existing depression, liver or heart diseases.

Frequently Asked Questions about COMEDOLYTIC Cream

  1. Does COMEDOLYTIC Cream topical treat sunburn?
  2. No, COMEDOLYTIC Cream topical is not used to treat sunburn. However, please consult your doctor before using COMEDOLYTIC Cream.

  3. How long is COMEDOLYTIC Cream prescribed?
  4. The duration of treatment depends on the severity of the condition. Therefore, please consult your doctor.

  5. Can I recommend COMEDOLYTIC Cream capsule to a person having acne symptoms?
  6. No, do not recommend COMEDOLYTIC Cream to a person with acne, as the severity of the condition may not be the same for every individual. However, do not recommend any drug without the doctor’s consent.

  7. Is it safe to use cosmetics while using COMEDOLYTIC Cream topical?
  8. It is advised not to apply any cosmetics for about 60 minutes after the use of COMEDOLYTIC Cream.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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