COMBOLIN Respule 5x2.5ml

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Drug Information for COMBOLIN Respule 5x2.5ml


  • COMBOLIN which contains Ipratropium bromide and Levosalbutamol which belongs to bronchodilators
  • It works by opening your airways







What COMBOLIN is used for?

  • It is used to treat Chronic Obstructive Pulmonary Disease(COPD)
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Talk to your doctor before using this medicine, if you:

  • are allergic to Ipratropium, Levosalbutamol, Atropine or any of the other ingredients
  • have a heart problem called ‘hypertrophic obstructive cardiomyopathy’
  • have a very fast heart beat
  • have glaucoma (increased pressure in the eye)
  • have diabetes
  • have an over-active thyroid gland
  • have problems passing urine
  • are undergoing surgery
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  • Do not use this medicine if you are pregnant, likely to get pregnant or are breast-feeding
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  • COMBOLIN is not recommended for children under 12 years of age
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  • You may feel dizzy, or have difficulty in focusing, or blurred vision while taking this medicine
  • If this happens do not drive or use tools or machines
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Tell your doctor if you are taking or have taken,

  • other medicines used for treating lung problems
  • steroid medicines such as prednisolone
  • diuretics such as furosemide, thiazides
  • fluoxetine used for depression
  • medicines called anti-cholinergic used to treat colic pain, parkinson’s disease, problems passing urine or lack of control of your bladder or bowels
  • propranolol used to treat heart problems, high blood pressure, anxiety or migraine
  • fenoterol used for breathing problems
  • digoxin used for heart failure
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  • Always take this medicine exactly as your doctor has told you
  • Do not swallow or give this medicine by injection
  • Open the pouch and remove the strip of unit dose vials
  • Carefully separate a new dose unit from the strip
  • Do not use if it is already open or if the liquid inside is discolored
  • Twist off the top
  • Always hold it upright while you do this
  • Squeeze all the contents of the dose unit into the nebulizer chamber
  • If your doctor has told you that your medicine needs to be diluted, you will be given ‘sterile sodium chloride 0.9%’ solution
  • Your doctor will tell you how to do this
  • After you have finished, dispose of any leftover medicine carefully
  • It is important to keep your nebulizer clean
  • If any of the liquid or mist accidentally gets into your eyes you may get painful, stinging or red eyes, dilated pupils, blurred vision, see colors or lights
  • If this happens, talk to your doctor for advice

If you take more COMBOLIN

  • If you use more of this medicine than you should, talk to a doctor or go to a hospital straight away

If you forget to take COMBOLIN

  • If you forget a dose, take it as soon as you remember it
  • However, if it is time for the next dose, skip the missed dose
  • Do not take a double dose to make up for a forgotten dose

If you stop taking COMBOLIN

  • Talk to your doctor before stopping this medicine
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Like all medicines, this medicine can cause side effects, although not everybody gets them





  • wheezing, difficulties in breathing
  • allergic reactions
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  • lactic acidosis which may cause hyperventilation
  • shortness of breath even though there may be improvement in your wheezing
  • cold feet and hands
  • irregular heartbeat or thirst
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  • feeling nervous, shaky or dizzy
  • dry mouth
  • cough, headache
  • nausea
  • throat irritation
  • increase in blood pressure
  • increased heart rate or uneven heart beats (palpitations)
  • voice problems (‘dysphonia’)
  • skin reactions
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  • irregular heart beat
  • regular but abnormally fast heart rate (supraventricular tachycardia)
  • chest pain (due to heart problems such as angina)
  • blurred vision, dilated pupils, glaucoma, painful, stinging, or red eyes, swelling of the eyes, see colours or lights
  • increased sweating
  • unexpected tightening of the chest immediately after inhaling the medicine
  • dry throat, swelling of the throat
  • difficulty in breathing or speaking due to a brief spasm of your vocal muscles
  • inflammation of the mouth
  • muscle cramps, muscle weakness and pain
  • difficulty in passing urine
  • fall in blood pressure
  • mood changes
  • unusually low levels of potassium in your blood (called ‘hypokalemia’)
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  • Store at room temperature (15-25°C)
  • Do not freeze
  • Do not use if the liquid is discolored
  • Keep out of reach of children
  • Do not use this medicine after the expiry date
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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