Recently Searched
Combipara T Tablet 10'S
Choose Generic substitutes to Save up to 50% off 
₹0
INTRODUCTION
COMBIPARA T TABLET contains Aceclofenac, Paracetamol (Acetaminophen), and Thiocolchicoside which belongs to the group of medicines called Non-steroidal Anti-inflammatory drugs and Muscle relaxants. COMBIPARA T TABLET is used in adults for the management of acute inflammatory and painful conditions associated with muscle spasms, such as lower back pain, muscle spasm due to any injury, neck and shoulder pain, sciatica (type of nerve pain), degenerative vertebral disorders, ankylosing spondylitis (chronic back pain due to fusion of some bones of the spine), osteoarthritis, and rheumatoid arthritis.
Avoid drinking alcohol while taking COMBIPARA T TABLET. COMBIPARA T TABLET is not recommended for use in patients suffering from stomach ulcers, intestinal bleeding or have a history of stomach ulcers, severe kidney problems, liver failure, bleeding disorders, peripheral arterial disease (problem with blood circulation), heart problems such as heart attack, stroke, blockages in blood vessels of brain or heart or had a history of heart surgery for clearing blockages, rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption, therefore consult your doctor before taking.
COMBIPARA T TABLET should be used with caution in patients suffering from liver and kidney problems, seizures, stomach and bowel disorders, asthma or breathing problems, blood disorders (porphyria), recovering from major surgery, and alcohol dependence. Therefore, consult your doctor before taking it.
COMBIPARA T TABLET is not recommended for use in pregnant or breastfeeding women; therefore, consult your doctor before taking it. COMBIPARA T TABLET is not recommended for use in children below 16 years of age. COMBIPARA T TABLET should be used with caution in elderly patients (>65 years). Therefore, consult your doctor before taking it.
The most common side effects after taking COMBIPARA T TABLET are dizziness, nausea, diarrhoea, drowsiness, and stomach pain. Consult your doctor immediately if you experience any side effects or an allergic reaction after taking this medicine.
USES OF COMBIPARA T TABLET
COMBIPARA T TABLET is used in adults for the management of acute inflammatory and painful conditions associated with muscle spasms such as:
- lower back pain
- muscle spasm due to any injury
- neck and shoulder pain
- sciatica (type of nerve pain)
- degenerative vertebral disorders
- ankylosing spondylitis (chronic back pain due to the fusion of some bones of the spine)
- osteoarthritis, and rheumatoid arthritis
HOW COMBIPARA T TABLET WORKS
COMBIPARA T TABLET contains Aceclofenac, Paracetamol (Acetaminophen), and Thiocolchicoside, which work together to reduce pain and inflammation. Paracetamol and aceclofenac stop the formation of pain and inflammation-causing chemicals called prostaglandins, and thiocolchicoside acts in the brain and spinal cord on GABA receptors and helps to relieve muscle stiffness and muscle spasms.
DIRECTIONS FOR USE
Take COMBIPARA T TABLET as advised by your physician. Take COMBIPARA T TABLET with meals or after meals. Swallow COMBIPARA T TABLET as a whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the exact dose and duration of treatment for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF COMBIPARA T TABLET
COMMON
- dizziness
- nausea
- diarrhoea
- drowsiness (somnolence)
- stomach pain
- increased liver enzymes
UNCOMMON
- gas (flatulence)
- constipation
- vomiting
- mouth ulcers
- rashes, itching, skin inflammation, hives
- allergic skin reactions
- increased blood urea and creatinine level
RARE
- low blood iron levels
- vision problems
- heart failure
- high blood pressure
- shortness of breath
- stomach ulcers and bleeding
- urticaria
Stop taking COMBIPARA T TABLET and consult your doctor immediately in case you experience:
- diarrhoea
- severe allergic reaction-symptoms include fever, difficulty breathing, wheezing, stomach pain, vomiting, and swelling of the face and throat
- severe skin reactions such as stevens-johnnson syndrome and toxic epidermal necrolysis. These are potentially life-threatening, and they develop quickly forming large blisters and the skin peels away easily. These may appear in the mouth, throat, or eyes. These can be accompanied by fever, headache and aching of the joints
- meningitis-symptoms include high fever, headache, vomiting, blotchy red rashes, neck stiffness, and sensitivity to light
- kidney failure
- passing blood in stools or black tarry stools
- vomiting blood or any dark particles
- indigestion and acidity
- stomach pain and other abdominal problems
- blood disorder-symptoms include extreme tiredness, breathlessness, joint pain, repeated bruising and infections, and unexplained bruising or bleeding
- liver problems-symptoms include sudden weight loss, loss of appetite, jaundice, and feeling sick
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink plenty of water or fruit juices to stay hydrated. Don’t take any medicine on your own for treating diarrhoea. However, contact your doctor if the diarrhoea worsens.
Headache
Rest and relax. Drink plenty of water and electrolytes. Apply a pain-relieving balm to the head if required. Do not consume alcohol. However, contact your doctor if your headache does not improve.
Nausea And Vomiting
Take the medicine with or after a meal. Stick to simple meals. Avoid eating oily or spicy food. However, contact your doctor if nausea and vomiting worsen.
Skin Rash Or Itching
Avoid taking hot showers because they can irritate the skin and scratch the affected area. Apply moisturising cream regularly. Contact your doctor if the itching persists.
Stomach Pain
Try to rest and relax. Consume small meals regularly. Keep a heating pad on your stomach. If the stomach pain does not go away, see your doctor.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedCOMBIPARA T TABLET is not recommended for use in pregnant and breastfeeding women, therefore consult your doctor before taking it.
BREASTFEEDING
ContraindicatedCOMBIPARA T TABLET is not recommended for use in breastfeeding women as it passes through breast milk, therefore consult your doctor before taking it.
DRIVING AND USING MACHINES
Use with CautionAvoid driving or operating machinery while taking COMBIPARA T TABLET as it may cause dizziness, nausea, or drowsiness.
ALCOHOL
Consult your doctorAvoid drinking alcohol while taking COMBIPARA T TABLET.
KIDNEY
ContraindicatedCOMBIPARA T TABLET is not recommended for patients suffering from severe kidney failure, therefore consult your doctor before taking it.
LIVER
ContraindicatedCOMBIPARA T TABLET is not recommended for patients suffering from liver failure, therefore consult your doctor before taking it.
ALLERGY
ContraindicatedDo not take COMBIPARA T TABLET if you are allergic to Aceclofenac, Paracetamol (Acetaminophen), Thiocolchicoside, other NSAIDs such as aspirin, diclofenac, or any other ingredients of COMBIPARA T TABLET.
LUNGS
Use with CautionCOMBIPARA T TABLET should be used with caution in patients suffering from asthma or breathing problems, therefore consult your doctor before taking it.
HEART DISEASE
ContraindicatedCOMBIPARA T TABLET is not recommended for use in patients suffering from heart problems such as heart attack, stroke, blockages in blood vessels of the heart or having a history of heart surgery for clearing blockages, therefore consult your doctor before taking it. COMBIPARA T TABLET is not recommended for patients suffering from heart problems such as angina, therefore consult your doctor before taking it.
OTHERS
COMBIPARA T TABLET is not recommended for use if you have:
- stomach ulcers, intestinal bleeding or have a history of stomach ulcers
- bleeding disorders
- peripheral arterial disease (problem with blood circulation)
- blockages in blood vessels of the brain
- rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption
Before taking COMBIPARA T TABLET inform your doctor if you have:
- seizures
- stomach and bowel disorders such as ulcerative colitis, Crohn's disease (inflammatory bowel diseases), ulceration, bleeding or perforation in the gut or bowel
- blood disorders (porphyria)
- recovering from major surgery
- alcohol dependence
- chicken pox
- diabetes
- smoking habit
- high blood pressure
- raised cholesterol or triglycerides
- blood clots (thrombus)
Use in paediatrics:
COMBIPARA T TABLET is not recommended for use in children below 16 years of age, therefore consult your doctor before taking it.
Use in geriatric:
COMBIPARA T TABLET should be used with caution in elderly patients (>65 years), therefore consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking COMBIPARA T TABLET, inform your doctor if you are taking any of the following medicine:
- non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen, and naproxen (medicines used for the treatment of pain and inflammation)
- zidovudine (a medicine used to treat HIV infection)
- antidiabetic medications such as metformin, glipizide, sitagliptin etc. (medicines used for the treatment of diabetes)
- cyclosporin, tacrolimus (medicines used for immune system suppression)
- steroids such as betamethasone, dexamethasone, estradiol, testosterone etc
- mifepristone (a medicine used to induce abortions)
- methotrexate (a medicine used for the treatment of cancer and autoimmune disorders)
- anticoagulants such as warfarin, and heparin (medicine that prevents blood from clotting)
- diuretics such as furosemide, spironolactone etc (medicines that help maintain body fluid balance)
- quinolone antibiotics such as ciprofloxacin, levofloxacin, etc (medicines used for the treatment of bacterial infections)
- antihypertensives such as losartan, enalapril, metoprolol, etc (medicines used for the treatment of high blood pressure)
- cardiac glycosides such as digoxin (medicines used for the treatment of irregular heartbeat and heart failure)
- anti-depressants such as lithium, fluoxetine, sertraline, etc (medicines used for the treatment of depression)
- colestyramine (a medicine used to lower cholesterol levels)
- metoclopramide and domperidone (medicines used for the treatment of nausea and vomiting)
Overdosage:
If you or anybody else accidentally takes too much of COMBIPARA T TABLET, then consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Aceclofenac, Paracetamol (Acetaminophen), Thiocolchicoside |
| Pharmacological Category | : | Non-steroidal Anti-inflammatory drugs, Muscle relaxants |
| Therapeutic Indication | : | Acute inflammatory and painful conditions and muscle spasms |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep COMBIPARA T TABLET out of reach from children
- Store COMBIPARA T TABLET below 30°C
FAQs ABOUT COMBIPARA T TABLET
Q: Can I take COMBIPARA T TABLET for a prolonged duration?
A: No, always take COMBIPARA T TABLET for the duration your doctor has suggested. Prolonged use (More than 7 days) of COMBIPARA T TABLET is not recommended.
Q: What is the best time to take COMBIPARA T TABLET?
A: Take COMBIPARA T TABLET preferably with meals or after meals to reduce side effects.
Q: Is COMBIPARA T TABLET safe for heart patients?
A: No, COMBIPARA T TABLET is not recommended for use in patients suffering from heart problems such as heart attack, stroke, blockages in blood vessels of the heart or who had a history of heart surgery for clearing blockages, therefore consult your doctor before taking.
Q: Can I use COMBIPARA T TABLET frozen shoulder?
A: Yes, you can use COMBIPARA T TABLET to relieve pain and discomfort associated with a frozen shoulder.
Q: What should I inform my doctor before taking COMBIPARA T TABLET?
A: Before taking COMBIPARA T TABLET, inform your doctor in case you have any pre-existing conditions like any diseases or allergies, alcohol use, and any other medicines that you might be taking it.
REFERENCES
1. KD Tripathi. Drugs Acting on Peripheral Nervous System. Essentials of Medical Pharmacology, 7th edition 2013. Page-358.
2. KD Tripathi. Non-steroidal Anti-steroidal Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology, 7th edition 2013. Page 204, 206.
3. Sanjeev Kumar, Seema Rani, Ramchander Siwach, Prem Verma. To compare the efficacy and safety of a fixed dose combination of thiocolchicoside and aceclofenac versus chlorzoxazone, aceclofenac and paracetamol in patients with acute lower backache associated with muscle spasm. National Centre for Biotechnology. NLM. National Institute of Health. Statpearls. July 2014. [Accessed on 2nd February 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137632/
4. Laboratories BTT. Electronic Medicines Compendium (EMC). [Revised in January 2016] [Accessed on 2nd February 2023] https://www.medicines.org.uk/emc/files/pil.2389.pdf
5. Crescent Pharma Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 2nd February 2023] https://www.medicines.org.uk/emc/files/pil.14044.pdf
6. Torrent Pharmaceuticals. Trizulu Tablet. (Aceclofenac + Paracetamol (Acetaminophen) + Thiocolchicoside). [Revised in May 2020] [Accessed on 2nd February 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2958.pdf
7. Sanofi Healthcare India Private Limited. Myoril Tablet (Thiocolchicoside). [Revised in November 2021] [Accessed on 2nd February 2023] https://www.sanofi.in/dam/jcr:59bd7929-a7a5-4049-9268-e9bb4e8b7206/Myoril%20Caps%20_API%20ccdsv4%20UNS%20rev%20Nov%202021.pdf
8. Reliable 1 Laboratories LLC. Paracetamol. [Revised in October 2021] [Accessed on 2nd February 2023] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25626b46-78f8-7226-e054-00144ff8d46c
9. IASIS pharma. Relief Capsules (Thiocolchicoside). [Revised in October 2014] [Accessed on 2nd February 2023] https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf
10. Thioford-AP (Aceclofenac + Paracetamol (Acetaminophen) + Thiocolchicoside). Leeford. [Accessed on 2nd February 2023] https://www.leeford.in/product/814/thioford-ap
AUTHOR DETAILS
Written By Dr. Dhivakaran R, BDS
Last updated on 04 Feb 2023 | 12:32 PM(IST)
ALTERNATE BRANDS View All
₹0
₹0
₹0
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
