COLOSPA 135MG contains Mebeverine hydrochloride which belongs to a group of medicines called antispasmodics. It helps to relax the muscles of the gastro-intestinal tract (gut). Anticholinergics are a group of medicines which acts on the neurotransmitter, acetylcholine. They are also called antispasmodics. Anticholinergics prevent impulses from the parasympathetic nervous system from reaching the smooth muscle by blocking the action of acetylcholine which is responsible for contractions, cramps or spasms.
It is used in conditions such as irritable bowel syndrome and similar problems such as chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Irritable bowel syndrome (IBS) is a very common condition which causes spasm and pain in the gut or intestine. The intestine is long muscular tube which food passes down and so it can be digested. If the intestine goes into spasm and squeezes too tightly, you get pain. This medicine works by relieving the spasm, pain and other symptoms of IBS. Most people will not have problems with this medicine, but some may get some side effects, such as difficulty in breathing, swelling of face, neck, tongue or throat, skin rash, red itchy skin.