Coekastle AX Tablet 10'S

INTRODUCTION

COEKASTLE AX TABLET is a combination of Ambroxol, Levocetirizine and Montelukast which belong to a group of medicines called Mucolytics, Antihistamines and Leukotriene receptor antagonists respectively. It is used to treat chronic obstructive pulmonary disorder, asthma, allergic rhinitis and bronchitis.

Chronic obstructive pulmonary disorder is a chronic inflammatory lung disease that causes obstructed airflow from the lungs which is generally characterized by symptoms such as breathing difficulty, cough, mucus production and wheezing.

Asthma is a lung disease which causes airways to get narrow, swollen and blocked by excess mucus that is characterized by symptoms such as breathing difficulty, cough and wheezing.

Bronchitis is an infection of the main airways of the lungs (bronchi) that cause airways to become irritated and inflamed which is generally characterized by symptoms such as cough, production of mucus, weakness, shortness of breath and chest discomfort.

Avoid taking COEKASTLE AX TABLET, if you are allergic to Ambroxol, Levocetirizine or Montelukast.

Before taking COEKASTLE AX TABLET inform your doctor if you have hepatic impairment and kidney problems such as renal impairment.

COEKASTLE AX TABLET should be used with caution during pregnancy only if it is clearly necessary. It is not recommended for use in breastfeeding women as it can pass through breast milk.

COEKASTLE AX TABLET is not recommended for use in children and adolescents (below 15 years). Consult your doctor before taking COEKASTLE AX TABLET.

The most common side effects of taking COEKASTLE AX TABLET are sleeplessness, skin rash, vomiting, abdominal pain, excess sleepiness, common cold and weakness. Consult your doctor if any of these above side effects gets worse.

USES OF COEKASTLE AX TABLET

It is used to treat:

• Chronic obstructive pulmonary disorder
• Asthma and allergic rhinitis
• Bronchitis

HOW COEKASTLE AX TABLET WORKS

COEKASTLE AX TABLET provides symptomatic relief from chronic obstructive pulmonary disorder, asthma, allergic rhinitis and bronchitis. Ambroxol provides relief from symptoms of nasal congestion, allergic cough and rhinorrhea by thinning and loosening the mucus in the nose, windpipe and lungs. Levocetirizine provides relief from itching, swelling and rashes by blocking the effects of a chemical messenger called histamine in the body (which is responsible for producing allergic reactions in the body). Montelukast prevents allergic rhinitis by blocking leukotriene (a chemical messenger) that results in the reduction of inflammation of the airways which provides relief to the symptoms associated with allergies.

DIRECTIONS FOR USE

Take COEKASTLE AX TABLET as advised by your physician. Swallow COEKASTLE AX TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF COEKASTLE AX TABLET

HOW TO MANAGE SIDE EFFECTS

Headache:

If COEKASTLE AX TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking COEKASTLE AX TABLET. If it lasts more than a week or severe, inform your doctor.

Dry mouth :

Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.

Nausea and Vomiting:

Try to take COEKASTLE AX TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult and inform your doctor if the symptom gets worse.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.

Tiredness:

Try to take rest and drink plenty of fluids. Avoid or limit the consumption of alcohol. Try to take COEKASTLE AX TABLET at a time when you can sit down (or lie down) when the symptoms are at their worst. Avoid driving or using tools or machinery until you feel well.

Indigestion:

Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea or alcohol and lose weight if you are obese. Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

COEKASTLE AX TABLET should be used with caution during pregnancy only if it is clearly necessary. Consult your doctor before taking COEKASTLE AX TABLET.

BREASTFEEDING

COEKASTLE AX TABLET is not recommended for use in breast-feeding women as it may pass through the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines as you may feel reduced mental alertness, dizziness and drowsiness after taking COEKASTLE AX TABLET.

ALCOHOL

Avoid consumption of alcohol while taking COEKASTLE AX TABLET because it may reduce mental alertness.

KIDNEY

COEKASTLE AX TABLET should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before taking COEKASTLE AX TABLET.

LIVER

COEKASTLE AX TABLET should be used with caution in patients with hepatic impairment. Consult your doctor before taking COEKASTLE AX TABLET.

ALLERGY

Do not take COEKASTLE AX TABLET if you are allergic to Ambroxol, Levocetirizine, Montelukast or any of its ingredients of this medicine.

INTERACTIONS

A. Drug - Drug Interactions:

Before taking COEKASTLE AX TABLET inform your doctor if you are taking any of the following medicine:

• antipyrine (used to decrease pain and inflammation)
• pseudoephedrine (medicine used to relieve nasal congestion caused by colds, allergies and hay fever)
• ketoconazole (used to treat fungal infections)
• theophylline (used to treat the symptoms of asthma, bronchitis and other lung diseases)
• cimetidine (medicine used to treat peptic ulcer and stomach acidity)
• amoxicillin, cefuroxime, erythromycin, azithromycin (medicines used to treat bacterial infections)
• ritonavir (used to treat HIV)
• acetyl-salicylic acid (used for mild to moderate pain and to treat fever)  
• medicines used to relieve pain, reduce inflammation and fever (Ex. ibuprofen, naproxen, diclofenac)
• phenobarbital, phenytoin (used for treatment of epilepsy)
• rifampicin (medicine used to treat tuberculosis and other infections)
• gemfibrozil (used for treatment of high cholesterol)

Overdosage:

If you or anyone else accidentally takes too much of COEKASTLE AX TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are drowsiness, abdominal pain, sleepiness, thirst, headache, vomiting and hyperactivity.

SYNOPSIS

MORE INFORMATION

• Keep the medicine out of reach in children
• Store COEKASTLE AX TABLET at room temperature

FAQs ABOUT COEKASTLE AX TABLET

Q: What COEKASTLE AX TABLET is used for?

A: COEKASTLE AX TABLET is used to treat chronic obstructive pulmonary disorder (inflammatory lung disease), asthma and allergic rhinitis which  is also used to treat bronchitis (viral lung disease).

Q: Who should avoid taking COEKASTLE AX TABLET?

A: COEKASTLE AX TABLET is not recommended for use in patients allergic to Ambroxol, Levocetirizine or Montelukast and recommended for use in breastfeeding women and in children and adolescents (below 15 years of age).

Q: What are the side effects of COEKASTLE AX TABLET?

A: The most common side effects of taking COEKASTLE AX TABLET are sleeplessness, skin rash, vomiting, abdominal pain, excess sleepiness, common cold and weakness. Consult and inform your doctor if any of these side effects gets worse.

Q: What happens if you take more COEKASTLE AX TABLET than your required dose?

A: If you or anyone else accidentally takes too much of COEKASTLE AX TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are drowsiness, abdominal pain, sleepiness, thirst, headache, vomiting and hyperactivity in adults.

Q: Can COEKASTLE AX TABLET be taken by pregnant or breastfeeding women?

A: COEKASTLE AX TABLET should be used with caution in pregnant women and recommended in breastfeeding women since it may pass through mother’s milk. Consult your doctor before taking this medicine.

REFERENCES

1. KD. Tripathi. Histamine &  Antihistaminics and Drugs for Cough and Bronchial Asthma. Seventh edition, 2013. Page – 167, 219 & 228.

2. Ahmad Kantar, Ludger Klimek, Dorotheea Cazan, Annette Sperl, Ulrike Sent and Margarida Mesquita. An overview of efficacy and safety of ambroxol for the treatment of acute and chronic respiratory diseases with a special regard to children. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in March 2020] [Accessed on 16th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137760/

3. UCB, Inc. U.S. Food & Drug Administration. [Revised in January 2008] [Accessed on 16th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022064s009lbl.pdf

4. La Renon Healthcare Pvt Ltd. Montegress- XL. [Revised in 2018] [Accessed on 16th June 2022] https://www.larenon.com/wp-content/uploads/2019/01/12.-MONTEGRESS-XL-LBL-FINAL.pdf

5. Amarox Limited. Electronic medicines compendium (EMC). [Revised in November 2020] [Accessed on 16th June 2022] https://www.medicines.org.uk/emc/files/pil.13555.pdf

USEFUL DIAGNOSTIC TESTS

• Sputum test

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 21 Jan 2023 | 06:00 PM(IST)