Cobix 200mg Capsule 10'S

Pain relief Rx required

Best Price*  ₹ 102.40
MRP ₹128.00
(Inclusive of all taxes) *10 Capsule(s) in a Strip * Mkt: Cipla Ltd (Generics) * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

COBIX 200MG contains Celecoxib which belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAID’s). It is indicated to treat osteoarthritis, rheumatoid arthritis. It is also indicated for juvenile rheumatoid arthritis, ankylosing spondylitis, acute pain, primary dysmenorrhea and familial adenomatous polyposis.

This medicine works by blocking the release of chemical messengers which are responsible for pain and inflammation (redness and swelling). COBIX 200MG has anti-inflammatory, analgesic and antipyretic properties. It works by decreasing the activity of the enzyme called cyclooxygenase-2 (COX-2) that inhibits the synthesis of prostaglandin which are responsible for pain and inflammation.

Always take this COBIX 200MG exactly as prescribed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. Your doctor will give the right dose depends on your child’s age and body weight. The common side effects are stomach pain, dizziness and diarrhoea.

USES OF COBIX 200MG

Treats,

  • osteoarthritis
  • rheumatoid arthritis
  • juvenile rheumatoid arthritis (in children)
  • ankylosing spondylitis
  • acute pain
  • primary dysmenorrhea and
  • familial adenomatous polyposis

HOW COBIX 200MG WORKS

COBIX 200MG has anti-inflammatory, analgesic and antipyretic properties. It works by decreasing the activity of the enzyme called cyclooxygenase-2 (COX-2) that inhibits the synthesis of prostaglandin which are responsible for pain and inflammation.

DIRECTIONS FOR USE

Always take COBIX 200MG exactly as your doctor has told you. Swallow as a whole and do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF COBIX 200MG

SERIOUS

  • allergic reactions
  • pain in the chest
  • stomach pain or bleeding in the stomach
  • liver failure

COMMON

  • dizziness
  • stomach ache
  • diarrhoea
  • indigestion
  • urinary infections
  • shortness of breath
  • blocked or runny nose or flulike symptoms
  • difficulty sleeping
  • vomiting
  • headache
  • painful joints
  • high blood pressure

RARE

  • ulcers (bleeding) in the stomach
  • low levels of sodium
  • reduced number of white blood cells
  • difficulty coordinating and muscular movements
  • loss of hair
  • hallucinations
  • bleeding in the eye
  • irregular heartbeat
  • flushing
  • severe liver inflammation
  • menstrual disturbances (in women)

HOW TO MANAGE SIDE EFFECTS

Indigestion:

Stick to simple normal meals and do not eat rich or spicy foods.

Stomach ache:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

Headache:

Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller.

WARNING & PRECAUTIONS

PREGNANCY

COBIX 200MG is not recommended for use in the 1st trimester of pregnancy. Discuss the risks and benefits with your doctor.

BREASTFEEDING

COBIX 200MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or handle any machines while taking this medicine it may cause dizziness or drowsiness.

ALCOHOL

Consumption of alcohol is not recommended during treatment with COBIX 200MG.

KIDNEY

COBIX 200MG is not recommended in patients with active kidney diseases. Discuss the risks and benefits with your doctor.

LIVER

COBIX 200MG is not recommended in patients with active liver diseases. Discuss the risks and benefits with your doctor.

ALLERGY

Do not take if you are allergic (hypersensitive) to Celecoxib.

HEART DISEASE

COBIX 200MG is not recommended in patients with active heart diseases. Discuss the risks and benefits with your doctor.

OTHERS

Inform your doctor if you have or had,

  • ulcer or bleeding in stomach or intestines
  • asthma, nose polyps
  • severe nose congestion
  • inflammatory diseases  
  • blood circulation (peripheral arterial disease)
  • diabetes
  • raised blood pressure
  • increased cholesterol

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

  • sulphonamides, rifampicin (used to treat infections)
  • dextromethorphan (used to treat coughs)
  • ACE inhibitors or angiotensin II antagonists, beta blockers and diuretics (used for high blood pressure and heart failure)
  • fluconazole (used to treat fungal infections)
  • warfarin, apixaban (used to thin blood)
  • lithium (used to treat depression)
  • neuroleptics (used to treat some mental disorders)
  • methotrexate (used to treat rheumatoid arthritis)
  • carbamazepine, barbiturates (used to treat epilepsy)
  • ciclosporin and tacrolimus (immune system suppression)

SYNOPSIS

Drug :   Celecoxib
Pharmacological Category :   Analgesic, Nonsteroidal Anti-inflammatory Drug
Therapeutic Indication :   Acute pain, Ankylosing spondylitis, Juvenile idiopathic arthritis, Osteoarthritis, Primary dysmenorrhea, Rheumatoid arthritis
Dosage Forms :   Tablet, Capsule

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT COBIX 200MG

Does COBIX 200MG cause drowsiness?

It may cause drowsiness, if you experience any symptoms consult your doctor for advice.

How does COBIX 200MG work?

It works by inhibiting the formation of chemicals called prostaglandins in the body that cause pain and inflammation, thereby reducing the pain and swelling symptoms.

How long does it take COBIX 200MG to start working?

It takes approximately 3 hours after oral administration to reach peak concentrations. The pain relieving effects lasts for approximately 12 hours.

REFERENCES

1. KD Tripathi MD. NSAIDs and antipyretic-analgesics. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 205.

2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 991.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 233-234.

4. Li Gong Caroline F. Thorn, Monica M. Bertagnolli, Tilo Grosser, Russ B. Altman and Teri E. Kleina. Celecoxib pathways: pharmacokinetics and pharmacodynamics. April 2012, [Accessed Jan 7, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303994/

5. Pfizer, G.D. Searle.LLC. 1998. U.S. Food & Drug Administration; [Revised Dec, 2008] [Accessed Jan 7, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020998s027lbl.pdf

6. G.D. Searle & Co. 1998; [Accessed Jan 7, 2021] https://oncozine.com/wp-content/uploads/2017/07/Package-Insert-celecoxib.pdf

7. Milpharm Limited. APL Swift Services (Malta) Limited; Electronic Medicines Compendium (EMC); [Revised July, 2018] [Accessed Jan 7, 2021] https://www.medicines.org.uk/emc/files/pil.2117.pdf 

USEFUL DIAGNOSTIC TESTS

  • Calcium
  • Rheumatoid Factor - Agglutination
  • Rheumatoid Factor - Turbidometry
  • Rheumatoid Factor IgG Antibody
  • Rheumatoid Factor IgM Antibody

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    17.5
    Ingredient
    CELECOXIB 200MG
    Hsn Code
    30049069
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Cobix 200mg Capsule 10'S

Cobix 200mg Capsule 10'S Mkt: Cipla Ltd (Generics)

M.R.P.: Rs.128.00
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