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INTRODUCTION

COBATUS OD TABLET contains Mecobalamin which belongs to the group of medicines called Vitamins. COBATUS OD TABLET is used to treat peripheral neuropathies (peripheral nerve damage that affects hands, feet and arms), and megaloblastic anaemia (blood disorder that occurs due to abnormal production of red blood cells) caused by vitamin B12 deficiency in affected individuals.

COBATUS OD TABLET is not recommended for use in patients allergic to Mecobalamin, and/or other B12 containing medicines. It also not recommended for use in patients with Leber’s disease (inherited form of vision loss).

Before taking COBATUS OD TABLET, inform your doctor if you are in an occupation of handling mercury, and/or have kidney problems (such as renal failure)/liver problems (such as hepatic impairment).

COBATUS OD TABLET is not recommended for use in pregnant and breastfeeding women. It should be used with caution in children and adolescents (aged 6 months to 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.

The most common side effects of taking COBATUS OD TABLET are weakness, headache, back pain, muscle pain, indigestion, nausea, and/or vomiting. Consult your doctor if any of these side effects worsens.

USES OF COBATUS OD TABLET

  • Treats peripheral neuropathies
  • Treats megaloblastic anaemia (caused by vitamin B12 deficiency) in affected individuals

HOW COBATUS OD TABLET WORKS

COBATUS OD TABLET works by aiding in the synthesis of myelin (lipid rich material that covers nerve fibres) which helps in protecting the nerve fibres and thereby providing relief from painful diabetic neuropathy in affected individuals.   It also promotes nucleic acid synthesis in the bone marrow which helps in the maturation and division of erythroblasts thus preventing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.

DIRECTIONS FOR USE

Tablet:

Take COBATUS OD TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Oral Disintegrating Tablet:

Take COBATUS OD TABLET as advised by your physician. Place COBATUS OD TABLET inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Sublingual Tablet:

Take COBATUS OD TABLET as advised by your physician. Place COBATUS OD TABLET under the tongue till it dissolves. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF COBATUS OD TABLET

COMMON

  • weakness, headache, back pain, generalized pain, muscle pain
  • infection
  • indigestion, nausea, vomiting, diarrhoea
  • swollen tongue, burning/prickling sensation
  • anorexia (eating disorder)
  • rash

HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.

Nausea And Vomiting

Take COBATUS OD TABLET with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Talk with your doctor if the condition worsens.

Headache

If COBATUS OD TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking COBATUS OD TABLET. If it lasts more than a week or severe, inform your doctor.

Indigestion

Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese.  Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY
Contraindicated

COBATUS OD TABLET is not recommended for use in pregnant women. Consult your doctor before taking COBATUS OD TABLET.

BREASTFEEDING
Contraindicated

COBATUS OD TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking COBATUS OD TABLET.

KIDNEY
Use with Caution

COBATUS OD TABLET should be used with caution in patients with kidney problems such as renal failure. Consult your doctor before taking the medicine.

LIVER
Use with Caution

COBATUS OD TABLET should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before taking the medicine.

ALLERGY
Contraindicated

Do not take COBATUS OD TABLET if you are allergic to mecobalamin, other B12 containing medicines, and/or any other ingredients of this medicine.

OTHERS

COBATUS OD TABLET is not recommended for use if you:

  • have Leber’s disease (inherited form of vision loss)

Before taking COBATUS OD TABLET, inform your doctor if you:    

  • are in an occupation of handling mercury

Use in Paediatrics:

COBATUS OD TABLET should be used with caution in children and adolescents (aged 6 months to 18 years). Consult your doctor before administering the medicine to the child.

Use in Geriatrics:

COBATUS OD TABLET should be used with caution in elderly patients (aged above 65years). Consult your doctor before taking the medicine.

INTERACTIONS

A. Drug-Drug interactions:

Before taking COBATUS OD TABLET, inform your doctor if you are taking any of the following medicine:

  • neomycin (used to prevent/treat bacterial skin infections)
  • amino salicylic acid (used to treat tuberculosis)
  • histamine H2-antagonists (used to treat and prevent recurrence of duodenal ulcers) Ex. ranitidine, famotidine 
  • colchicine (used in the treatment of gout)
  • oral contraceptives (used to prevent pregnancy) Ex. ethinyl estradiol and norethindrone
  • chloramphenicol (used to treat bacterial infections)
  • omeprazole (used to treat gastric & duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease)

Overdosage:

If you or anyone else accidentally take too much of COBATUS OD TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

SYNOPSIS

Drug :   Mecobalamin
Pharmacological Category :   Vitamin B12
Therapeutic Indication :   Peripheral neuropathy, Megaloblastic anaemia
Dosage Forms :   Tablet, Oral disintegrating strip, Injection, Nasal spray

MORE INFORMATION

  • Keep COBATUS OD TABLET out of reach of children
  • Store COBATUS OD TABLET below 30°C

FAQs ABOUT COBATUS OD TABLET

Q. What is COBATUS OD TABLET used for?

A. COBATUS OD TABLET is used to treat peripheral neuropathies (peripheral nerve damage that affects hands, feet and arms), and megaloblastic anaemia (blood disorder that occurs due to abnormal production of red blood cells) which occurs due to deficiency of vitamin B12 in affected individuals.

Q. How COBATUS OD TABLET be taken?

A. Tablet:

Take COBATUS OD TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Oral Disintegrating Tablet:

Take COBATUS OD TABLET as advised by your physician. Place COBATUS OD TABLET inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Sublingual Tablet:

Take COBATUS OD TABLET as advised by your physician. Place COBATUS OD TABLET under the tongue till it dissolves. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q. What are the side effects of COBATUS OD TABLET?

A. The most common side effects of taking COBATUS OD TABLET are weakness, headache, back pain, muscle pain, indigestion, nausea, and/or vomiting. Consult your doctor if any of these side effects worsens.

Q. How COBATUS OD TABLET works?

A. COBATUS OD TABLET works by aiding in the synthesis of myelin (lipid rich material that covers nerve fibres) which helps in protecting the nerve fibres and thereby providing relief from painful diabetic neuropathy in affected individuals.   It also promotes nucleic acid synthesis in the bone marrow which helps in the maturation and division of erythroblasts thus preventing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.

Q. Can COBATUS OD TABLET be used in pregnant and breastfeeding women?

A. No, COBATUS OD TABLET is not recommended for use in pregnant and breastfeeding women since it may cause some undesirable effects to the foetus and breastfed baby. Consul your doctor before taking COBATUS OD TABLET.

REFERENCES

1. KD. Tripathi. Drugs affecting blood and blood formation, Vitamins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 606.

2. Advait Vasavada; Devang Sanghavi. Cyanocobalamin.  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. September 2022. [Accessed on 4th November 2022] https://www.ncbi.nlm.nih.gov/books/NBK555964/

3. A S M Al Amin; Vikas Gupta. Vitamin B12 (Cobalamin).  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed on 4th November 2022] https://www.ncbi.nlm.nih.gov/books/NBK559132/

4. Rabia G Sezer, Abdulkadir Bozaykut, Handan A Akoglu, Gül N Özdemir. The Efficacy of Oral Vitamin B12 Replacement for Nutritional Vitamin B12 Deficiency.  NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov.  March 2018. [Accessed on 4th November 2022] https://pubmed.ncbi.nlm.nih.gov/29189512/

5. Emmanuel Andrès, Thomas Vogel, Laure Federici, Jacques Zimmer,  Ecaterina Ciobanu, and Georges Kaltenbach. Cobalamin Deficiency in Elderly Patients: A Personal View. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. May 2008.  [Accessed on 4th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672039/

6. Getz Pharma (Pvt) Ltd. Nervon. [Accessed on 4th November 2022] https://getzpharma.com/wp-content/uploads/2016/08/Nervon-Range-Leaflet-Export-GA.pdf

7. Mova Pharmaceutical Pvt Ltd. MOVACOBAL MD 3. [Accessed on 4th November 2022] http://movapharma.com/cod-division.php

8. Micro Labs Ltd. Meconerv Tablet. [Accessed on 4th November 2022] https://www.microlabsltd.com/elibrary/node/1908

9. Kivonyx Healthcare. Vibicol SL. [Accessed on 4th November 2022] https://www.kivonyx.com/product/Vibicol-SL

USEFUL DIAGNOSTIC TESTS

  • Nerve conduction test
  • Complete blood count

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    MECOBALAMIN (METHYLCOBALAMIN) 1500MCG
    Hsn Code
    30045090
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Cobatus OD Tablet 10'S

Cobatus OD Tablet 10'S Mkt: Icon Life Sciences

₹73.00 MRP₹ 944.89
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