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CLOVIVA PLUS CREAM is a combination of Clobetasol and Gentamicin which belongs to the group of medicines called Corticosteroids and Antibiotics respectively. It is used to treat bacterial infections and inflammations of the skin.
During the treatment your doctor might regularly examine your skin to avoid any untoward side effects.
Avoid smoking while using CLOVIVA PLUS CREAM. Consult your doctor before using this medicine.
CLOVIVA PLUS CREAM is not recommended for use in children (ages less than 1 year). Before using CLOVIVA PLUS CREAM, inform your doctor if you have skin conditions like fungal infections, severe flushing on and around your nose, spotty red rash around your mouth, infected or itchy skin around the genitals.
CLOVIVA PLUS CREAM should be used with caution in pregnant women. CLOVIVA PLUS CREAM is not recommended for use in breastfeeding women.
The most common side effects of using CLOVIVA PLUS CREAM are burning, pain, irritation or itching where the medicine is applied. Contact your doctor if any of the side effects worsen.
CLOVIVA PLUS CREAM treats affected skin where Clobetasol induces certain proteins (lipocortins), that control the production of inflammatory mediators like prostaglandins and leukotrienes, thus reducing inflammation, and Gentamicin binds to 30s ribosomal subunit, disrupting mRNA translation, resulting in the formation of shortened or non-functional proteins.
Apply CLOVIVA PLUS CREAM as directed by your physician. It is for external use only. Apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes. Your doctor will decide the right dose depends on your age, body weight and severity of infection.
Stop using CLOVIVA PLUS CREAM and consult your doctor immediately if you experience any of the following side effects:
CLOVIVA PLUS CREAM should be used with caution in pregnant women. Consult your doctor before using the medicine.
CLOVIVA PLUS CREAM is not recommended for use in breastfeeding women. Consult your doctor before using the medicine.
Do not use CLOVIVA PLUS CREAM if you are allergic to Clobetasol, Gentamicin, or any other ingredients of this medicine.
CLOVIVA PLUS CREAM is not recommended for use if you:
Before using CLOVIVA PLUS CREAM inform your doctor if you:
Use in Pediatrics:
CLOVIVA PLUS CREAM is not recommended for use in children (less than 1 year of age). Consult your doctor before using the medicine.
A. Drug-Drug interactions:
Before using CLOVIVA PLUS CREAM, inform your doctor if you are taking any of the following medicine:
If you or anyone else accidentally applies too much of CLOVIVA PLUS CREAM, contact your doctor immediately or visit nearby hospital.
|Pharmacological Category||:||Corticosteroid, Antibiotics|
|Therapeutic Indication||:||Bacterial skin infections|
Q: For how long can I use CLOVIVA PLUS CREAM?
A: Use CLOVIVA PLUS CREAM for as long as your doctor advises you to. If you use it over a long time or in large amounts it may increase your chances of getting side effects, and your skin may get more sensitive to the medicine.
Q: What special precautions should I take while using CLOVIVA PLUS CREAM?
A: Take special care if you are going to use CLOVIVA PLUS CREAM near your eyes. Do not smoke or go near flames as it may cause severe burns. Consult your doctor in case of any concerns.
Q: What if I accidently get CLOVIVA PLUS CREAM in my eye?
A: If you accidentally get CLOVIVA PLUS CREAM in your eye, immediately wash it out with plenty of water. If you begin to have any problems with your sight or your eye is hurting, contact your doctor immediately.
Q: Can I stop using CLOVIVA PLUS CREAM?
A: Do not stop using CLOVIVA PLUS CREAM without asking your doctor as abrupt discontinuation might worsen your condition. If you have any more doubts regarding the use of this medicine, ask your doctor.
Q: What if I forget to apply a dose of CLOVIVA PLUS CREAM?
A: If you forget to apply a dose of CLOVIVA PLUS CREAM, do it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not apply extra medicine to make up for a forgotten dose.
Q: Can CLOVIVA PLUS CREAM be used on infants?
A: No. CLOVIVA PLUS CREAM is not recommended for children (below 1 year of age). Your doctor will decide the correct dose or select a suitable alternative therapy for your child.
Q: Can CLOVIVA PLUS CREAM be used in breastfeeding?
A: CLOVIVA PLUS CREAM is not recommended for use during breast feeding. Do not apply it on your breast area so that the baby does not accidentally ingest the medicine.
1. KD. Tripathi. Aminoglycosides Antibiotics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 747.
2. PubChem Compound Summary for CID 5311051, Clobetasol. National Center for Biotechnology Information. June 2022. [Accessed on 27th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Clobetasol#section=Mechanism-of-Action
3. Bruno J. Chaves; Prasanna Tadi. Gentamicin. StatPearls [Internet]. StatPearls Publishing. May 2022. [Accessed on 27th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK557550/#article-22211.s3
4. Glaxo Operations UK Limited. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 27th June 2022] https://www.medicines.org.uk/emc/files/pil.939.pdf
5. Padagis Israel Pharmaceuticals Ltd. Gentamicin. [Revised in September 2021] [Accessed on 27th June 2022] file:///C:/Users/NMSLAP468/Downloads/20210925_4cfbe37e-11d6-46fc-b287-0561387b17b7.pdf
6. Wellona Pharma. Clobetasol propionate + Gentamicin. [Accessed on 27th June 2022] https://wellonapharma.com/product/finished/clobetasol-propionate-and-gentamicin-cream
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