INTRODUCTION

CLOTROL F CREAM is a combination of Clobetasol and Fusidic acid which belongs to the group of medicines called Corticosteroids and Antibiotics respectively. It is used to treat skin infections such as impetigo (crusty and swollen patch on the skin with pus), psoriasis (itching), eczema, or dermatitis. It can also be used to treat cuts and wounds which are infected.

Eczema or dermatitis is a term for several different types of skin swelling that cause dry, itchy skin and rashes on the face, elbows, behind the knees, and on the hands and feet.

During course of the treatment your doctor might regularly examine your skin to avoid any unwanted side effects.

Avoid smoking while using CLOTROL F CREAM. Consult your doctor before using the medicine.

CLOTROL F CREAM is not recommended for use in children (ages less than 1 year). Before using CLOTROL F CREAM, inform your doctor if you have skin conditions like acne, rosacea, perioral dermatitis, viral or fungal skin infections, blisters caused by any infection, or if you are using it on your child.

CLOTROL F CREAM should be used with caution in pregnant women. CLOTROL F CREAM is not recommended for use in breastfeeding women.

The most common side effect of using CLOTROL F CREAM is skin irritation. Contact your doctor if any of the side effects worsen.

USES OF CLOTROL F CREAM

It is used to treat skin conditions such as:

• impetigo
• psoriasis
• eczema, or dermatitis
• infected cuts and wounds

HOW CLOTROL F CREAM WORKS

CLOTROL F CREAM treats skin infection where Clobetasol induces certain proteins (lipocortins), that control the production of inflammatory mediators like prostaglandins and leukotrienes, thus controlling inflammation, and Fusidic acid works against the bacteria by interfering with their protein synthesis.

DIRECTIONS FOR USE

Use CLOTROL F CREAM as directed by the physician. It is for external use only. Clean and dry the affected area and apply the medicine. Check the label for directions before use. Your doctor will decide the right dose depends on the age, body weight and disease condition.

SIDE EFFECTS OF CLOTROL F CREAM

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before using CLOTROL F CREAM, inform your doctor if you are using, have used, or might use any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

If you or anyone else accidentally use too much of CLOTROL F CREAM, contact your doctor immediately.

SYNOPSIS

MORE INFORMATION

• Keep CLOTROL F CREAM out of reach of children
• Do not store above 30°C

FAQs ABOUT CLOTROL F CREAM

For how long can I use CLOTROL F CREAM?

Use CLOTROL F CREAM for as long as your doctor advises you to. If you use it over a long time or in large amounts it may increase your chances of getting side effects, and your skin may get more sensitive to the medicine. You should not use it for a long time on your face.

What special precautions should I take while using CLOTROL F CREAM?

Take special care if you are going to use CLOTROL F CREAM near your eyes. Do not smoke or go near flames as it may cause severe burns. Cloth that has been in contact with this medicine burns more easily and is a serious fire hazard. Consult your doctor in case of any concerns.

What if I accidently get CLOTROL F CREAM in my eye?

If you accidentally get CLOTROL F CREAM in your eye, immediately wash it out with cold water. Then wash your eye with eyewash if possible. You may feel stinging in your eye. If you begin to have any problems with your sight or your eye is hurting, contact your doctor immediately.

Can I stop using CLOTROL F CREAM?

Do not stop using CLOTROL F CREAM unless your doctor advises you to stop. If you have any more doubts regarding the use of this medicine, ask your doctor.

What if I forget to apply a dose of CLOTROL F CREAM?

If you forget to apply a dose of CLOTROL F CREAM, do it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not use the medicine twice to make up for a forgotten dose.

Can CLOTROL F CREAM be used on infants?

No. CLOTROL F CREAM is not recommended for children (below 1 year of age). Your doctor will decide the correct dose or select a suitable alternative therapy for your child.

Can CLOTROL F CREAM be used in breastfeeding?

Before using CLOTROL F CREAM, inform your doctor if you are breast-feeding, or are planning to do so. CLOTROL F CREAM is not recommended for use during breast feeding. If you do use it when breast-feeding, do not apply it on your breast area so that the baby does not accidentally ingest the medicine.

REFERENCES

1. KD. Tripathi. Macrolide and other Antibacterial Antibiotics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 759.

2. PubChem Compound Summary for CID 5311051, Clobetasol. National Center for Biotechnology Information. June 2022. [Accessed on 25th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Clobetasol#section=Mechanism-of-Action

3. LEO Laboratories Limited. Electronic Medicines Compendium (EMC). [Revised in November 2019] [Accessed on 25th June 2022] https://www.medicines.org.uk/emc/files/pil.5510.pdf

4. Tiofarma B.V. Health Products Regulatory Authority (HPRA). [Revised in January 2018] [Accessed on 25th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/pil-2192536-14022018143249-636542155701250000.pdf

USEFUL DIAGNOSTIC TESTS

• Patch testing