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Drug Information

What is Zuclopenthixol used for?

Zuclopenthixol is used for the treatment of psychological disorders, such as psychosis, mania and schizophrenia.

Zuclopenthixol may also be prescribed for other conditions as determined by the doctor.

How does Zuclopenthixol work?

Zuclopenthixol belongs to the class of drugs called anti-psychotic agents. This drug acts by blocking dopamine and other neurotransmitters in the brain. It also increases the blood flow to the brain. Thus, it promotes mood and calms down the individual.

How to administer Zuclopenthixol?

The dosage and the drug form depend on the age, weight and medical condition of an individual.

Zuclopenthixol injection should be administered only under the supervision of a healthcare provider. Do not self-medicate.

In case of a missed dose, please contact your healthcare provider.

The overdose symptoms of Zuclopenthixol may include:

  • Convulsions
  • Drowsiness
  • Extrapyramidal symptoms
  • Hyperthermia
  • Hypotension
  • Hypothermia
  • Increased heart rate
  • Muscle stiffness
  • Seizures
  • Shock
  • Somnolence
  • Unconsciousness

You must seek immediate medical care if you experience any of the above symptoms.

What are the drugs that interact with Zuclopenthixol?

Drugs that interact with Zuclopenthixol include the following:

  • Apomorphine
  • Cisapride
  • Clozapine
  • Erythromycin
  • Guanethidine
  • Levodopa
  • Lithium
  • Methadone
  • Metoclopramide
  • Moxifloxacin
  • Piperazine
  • Saquinavir

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Zuclopenthixol?

The following are the most common side effects of Zuclopenthixol:

  • Abdominal pain
  • Abnormal reflexes
  • Anxiety
  • Changes in appetite
  • Changes in walking pattern
  • Constipation
  • Diarrhoea
  • Difficulty in breathing
  • Dizziness
  • Drowsiness
  • Fainting
  • Flatulence
  • Headache
  • High fever
  • Hyperprolactinemia
  • Increased heart rate
  • Increased or decreased saliva production
  • Increased thirst
  • Indigestion
  • Insomnia
  • Muscle stiffness
  • Nausea
  • Numbness of the limbs
  • Pain at the injection site
  • Postural hypotension
  • Shortness of breath
  • Slurry speech
  • Urinary incontinence
  • Vertigo
  • Vomiting

The following are the severe side effects and you may require immediate medical attention:

  • Blood dyscrasia
  • Blurry vision
  • Breast enlargement in men
  • Liver enlargement
  • Neuroleptic malignant syndrome
  • Problems in penis erection and ejaculation
  • Seizures
  • Sexual dysfunction
  • Swelling of the face, lips and throat
  • Tardive dyskinesia

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while receiving Zuclopenthixol?

  • Avoid using the medicine if you are allergic to Zuclopenthixol or similar drugs.
  • Avoid consumption of alcohol as it may alter the absorption of Zuclopenthixol.
  • Do not drive or operate heavy machinery if Zuclopenthixol causes dizziness or blurred vision.
  • Avoid Zuclopenthixol during pregnancy or breastfeeding as the safe use of the drug is not yet established.
  • Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
  • Do not exceed the dose more than what is prescribed.
  • Be cautious while taking Zuclopenthixol if you have any kidney or liver impairment.

You are advised not to receive Zuclopenthixol if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before receiving Zuclopenthixol?

  • Tell your doctor if you have any history of heart, liver and kidney disorders.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform the doctor if you have any history of allergic reaction with the usage of Zuclopenthixol.
  • Notify the doctor if you are pregnant or breastfeeding.

Frequently asked questions about Zuclopenthixol

  1. Should I follow any special dietary instructions while receiving Zuclopenthixol?
  2. Avoid consumption of alcohol while using Zuclopenthixol injection, as it increases the risk of the positive or negative effect of the drug in the body.

  3. I am on Zuclopenthixol for schizophrenia. Can I stop the drug if I feel better?
  4. It is not advised to immediately stop receiving Zuclopenthixol injection once you feel better.

  5. Can I alter the dose of Zuclopenthixol?
  6. No, it is not advised to alter the dose of Zuclopenthixol without doctor’s consent.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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