INTRODUCTION

CLINVAN contains Clindamycin which belongs to the group of medicines called Topical antibiotics. It is used for the topical treatment of acne vulgaris. Acne vulgaris is a common skin condition that occurs in teens, when hair follicles of the skin plug with oil and dead skin cells. Symptoms includes inflammation, large, reddish pus-filled pimples and formation of comedones.

CLINVAN effectively removes dark spots, blackheads and impurities present in the skin. It also has anti-inflammatory and rapid healing action and prevents further bacterial infection. It is a mild cleanser with deep moisturizing properties. Clindamycin kills the pimple-causing bacteria by inhibiting the bacterial protein synthesis. If your skin feels too dry after using this soap, you can apply a moisturizer suitable for you.

Along with the treatment, try to eat less oily or spicy food. Avoid oil-based cosmetics and make-up products to achieve better results. It may cause application site reactions such as itching, redness or burning sensation in some individuals. It is usually temporary and disappears with time. Although it is a safe medicine, it may very rarely cause bowel problems which should be informed to doctor immediately. CLINVAN should be used with caution in children and adolescents under 18 years. Consult your doctor before using.

USES OF CLINVAN

• Treats acne, dark spots, blackheads
• Deeply cleanses your skin

HOW CLINVAN WORKS

Clindamycin kills the acne-producing bacteria by inhibiting the bacterial protein synthesis. It acts by reversibly binding to the 50S ribosomal subunits of the bacteria, which prevents peptide bond formation thus inhibiting bacterial protein synthesis. Inhibition of protein synthesis stops the growth of acne-producing bacteria leading to prevention of acne outbreaks.

DIRECTIONS FOR USE

Use this soap as directed by your physician. It is for external use only. Wet your face or other body parts with water. Gently rub the soap all over the body and generate lather. Massage the lather well to remove dirt, oil and impurities in the skin. Wash it thoroughly with water and pat dry. If your skin feels too dry after using this soap, you can apply a moisturizer suitable for you. Continue to use this soap, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF CLINVAN

HOW TO MANAGE SIDE EFFECTS

Skin redness, itching or burning:

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your healthcare provider if you are using any other topical preparations.

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT CLINVAN

Can I use CLINVAN on my face?

Yes. This soap can be used on your face to remove oil, dirt, impurities and to prevent acne outbreaks.

How to use CLINVAN?

Wet your face or other body parts with water. Gently rub the soap all over the body and generate lather. Massage the lather well to remove dirt, oil and impurities in the skin. Wash it thoroughly with water and pat dry. If your skin feels too dry after using this soap, you can apply a moisturizer suitable for you. Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results.

Can I apply moisturizer after applying CLINVAN?

Yes. If your skin feels too dry after using this medicine, you can apply a moisturizer to soothe and hydrate the affected area.

REFERENCES

1. KD. Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 756-757.

2. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 894.

3. Conan MacDougall and Henry F. Chambers. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1534-1535.

4. Gerald G. Briggs and Roger K. Freeman. C. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 856-857.

5. Akorn, Inc. Bioequivalence Study of Clindamycin Gel 1% in Treatment of Acne Vulgaris. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on October 2020] [Accessed 10th December 2020] https://clinicaltrials.gov/ct2/show/NCT03522441

6. R I Frankel. Clindamycin--efficacy and toxicity. NCBI; PMC US National Library of Medicine, National Institute of Health. June 1975. [Accessed 10th December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129812/?page=1

7. Avencerlabs. Clinvan Soap. Avencer Labs Pvt Ltd. [Accessed 10th December 2020] http://avancerlabs.in/details.php?proid=Mzgw