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INTRODUCTION
CLINPEU 300 CAPSULEcontains Clindamycin, which belongs to the group of medicines called Antibiotics. It is used to kill certain serious bacterial infections. Symptoms include fever, fatigue, headache, nausea, vomiting and swollen lymph nodes in the neck, armpits, groin or elsewhere.
Before taking CLINPEU 300 CAPSULE, inform your doctor if you have or ever had problems with your stomach or intestines (bowel disease, diarrhea), hay fever, asthma, eczema, intolerance to certain sugars, kidney, and liver problems. CLINPEU 300 CAPSULE should be used with caution in pregnant women. Consult your doctor before taking CLINPEU 300 CAPSULE.
CLINPEU 300 CAPSULE is generally not recommended for use in breastfeeding women. The most common side effects of taking CLINPEU 300 CAPSULE are diarrhea, stomach pain and abnormal liver function tests. Consult your doctor if your symptoms get worse or persist.
USES OF CLINPEU 300 CAPSULE
- Treats severe bacterial infections
HOW CLINPEU 300 CAPSULE WORKS
CLINPEU 300 CAPSULE acts against the bacteria by binding to the 50S subunit of the bacterial ribosome (site of protein synthesis). Which in turn prevents protein synthesis and kills the infection-causing bacteria.
DIRECTIONS FOR USE
Take CLINPEU 300 CAPSULE as advised by your physician. Swallow it with a full glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF CLINPEU 300 CAPSULE
COMMON
- diarrhea
- stomach pain
- abnormal liver function test
UNCOMMON
- vomiting
- feeling sick
- smooth skin rashes or redness covered with elevated bumps
- hives
RARE
Stop taking CLINPEU 300 CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- severe, continuous, bloody diarrhea (with stomach pain or fever). It can be a sign of serious bowel inflammation (pseudomembranous colitis).
- a severe allergic reaction such as sudden wheezing, difficulty in breathing, dizziness, swelling of the eyelids, face, lips, throat or tongue, rash, or itching (especially if affecting the entire body)
- jaundice (yellowing of the skin and whites of the eyes)
- skin rashes which can be severe or life-threatening:
- Stevens-Johnson syndrome (peeling of large areas of skin, especially around the mouth, nose, eyes, and genitals) and a more severe form (toxic epidermal necrolysis)
- the rapid appearance of areas of red skin with small pustules (blisters filled with white/yellow fluid) (Acute Generalized Exanthematous Pustulosis (AGEP))
- widespread red skin rash with pus-containing blisters (exfoliative dermatitis bullous)
- skin rash, which may blister (looks like central dark spots surrounded by a paler area, with a dark ring around the edge, known as erythema multiforme)
- drug reaction with eosinophilia and systemic symptoms (fever, swollen lymph nodes or skin rash)
HOW TO MANAGE SIDE EFFECTS
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor if your symptoms don't improve.
Stomach pain:
Try to rest and relax. Have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
CLINPEU 300 CAPSULE should be used with caution in pregnant women or women planning to have a baby as it crosses the placenta. It will be given to you by the doctor only if it's clearly necessary. Consult your doctor before taking CLINPEU 300 CAPSULE.
BREASTFEEDING
CLINPEU 300 CAPSULE is not recommended for use in breastfeeding women as it may pass into breast milk. Consult your doctor before taking CLINPEU 300 CAPSULE.
DRIVING AND USING MACHINES
CLINPEU 300 CAPSULE does not affect your ability to drive or use machines.
KIDNEY
CLINPEU 300 CAPSULEshould be used with caution in patients with severe kidney disease. Your doctor will give the right dose depending on your age, body weight and disease condition. Consult your doctor before taking CLINPEU 300 CAPSULE.
LIVER
CLINPEU 300 CAPSULE should be used with caution in patients with severe liver problems. Your doctor will give the right dose depending on your age, body weight and disease condition. Consult your doctor before taking CLINPEU 300 CAPSULE.
ALLERGY
Do not take CLINPEU 300 CAPSULE if you are allergic to Clindamycin or any other ingredients of this medicine.
OTHERS
Before taking CLINPEU 300 CAPSULE, inform your doctor if you:
- you have an intolerance to some sugars
- have diarrhea or have ever suffered from problems with your stomach or intestines (bowel disease)
- have hay fever, asthma, or eczema
Use in pediatrics:
Your doctor will give the right dose depending on your age, body weight and disease condition CLINPEU 300 CAPSULE Consult your doctor before taking CLINPEU 300 CAPSULE.
Use in geriatrics:
Your doctor will give the right dose depending on your age, body weight and disease condition CLINPEU 300 CAPSULE Consult your doctor before taking CLINPEU 300 CAPSULE.
INTERACTIONS
A. Drug - Drug interactions:
Before taking CLINPEU 300 CAPSULE, inform your doctor if you are taking any of the following medicine:
- erythromycin (an antibiotic used to treat infection)
- warfarin (blood thinners)
- muscle relaxants used for operations. (Ex. cyclobenzaprine)
Overdosage:
If you or anyone else accidentally takes too much CLINPEU 300 CAPSULE, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Clindamycin |
| Pharmacological Category | : | Lincosamides |
| Therapeutic Indication | : | Serious bacterial infections |
| Dosage Forms | : | Injection, Tablet, Capsule, Gel, Cream, Lotion, Solution, Spray, Soap |
MORE INFORMATION
- Keep CLINPEU 300 CAPSULE out of reach from children
- Do not store above 30°C
FAQs ABOUT CLINPEU 300 CAPSULE
What is CLINPEU 300 CAPSULE used for?
CLINPEU 300 CAPSULE is used to treat serious bacterial infections. A bacterial infection occurs when bacteria enter the body, increase in number and causing a reaction in the body. Symptoms include fever, fatigue, headache, nausea, vomiting and swollen lymph nodes in the neck, armpits, groin or elsewhere.
Are there any side effects of taking CLINPEU 300 CAPSULE?
The most common side effects of taking CLINPEU 300 CAPSULE are diarrhea, stomach pain and abnormal liver function test. Consult your doctor if symptoms do not improve.
How does CLINPEU 300 CAPSULE work?
CLINPEU 300 CAPSULE acts against the bacteria by binding to the 50S subunit of the bacterial ribosome (site of protein synthesis). Which in turn prevents protein synthesis and kills the infection-causing bacteria.
Can CLINPEU 300 CAPSULE be used in pregnancy?
CLINPEU 300 CAPSULE should be used with caution in pregnant women or women planning to have a baby as it crosses the placenta. It will be recommended to you by the doctor only if it's clearly necessary. Consult your doctor before taking CLINPEU 300 CAPSULE.
Can CLINPEU 300 CAPSULE be used in patients with kidney problems?
CLINPEU 300 CAPSULEshould be used with caution in patients with severe kidney disease. Your doctor will give you the right dose depending on your age, body weight and disease condition. Consult your doctor before taking CLINPEU 300 CAPSULE.
REFERENCES
1. KD Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Anti bacteria In Antibiotics. Urinary Antiseptics. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page –805-806.
2. Patrick B, Murphy, Karlyle G. Bistas, Jacqueline K.Le. Clindamycin. National Library of medicine, National center for biotechnology information. [Revised in July 2021] [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK519574/
3. Manuel Polanco Morales, Anna Paola Thome Carvallo, Karla Adriana Bautista Espinosa,and Edgar Enrique Meza Murillo. A young man with myelosuppression caused by clindamycin: a case report. National Library of medicine, National center for biotechnology information. Pubmed Central 2014 [Accessed on 10th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917410/
4. Laboratories BTT. Electronic Medicines Compendium (EMC). [Revised in May 2018] [Accessed on 10th May 2022] https://www.medicines.org.uk/emc/files/pil.2486.pdf
5. Laboratories BTT. Electronic Medicines Compendium (EMC). [Revised in May 2018] [Accessed on 10th May 2022] https://www.medicines.org.uk/emc/files/pil.2485.pdf, https://www.medicines.org.uk/emc/product/2485/smpc
Clindamycin. Healthdirect. [Revised in August 2020] [Accessed on 10th May 2022] https://www.healthdirect.gov.au/bacterial-infections
USEFUL DIAGNOSTIC TESTS
- Complete blood count test
- Liver function test
- Kidney function test
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