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Drug Information for CLINDAPENE Gel 15gm

What is CLINDAPENE Gel used for?

CLINDAPENE Gel is used for the treatment of Acne vulgaris when comedones (blackheads and whiteheads), papules (pimple) and pustules (small swelling containing pus or fluid) are present on the skin.

CLINDAPENE Gel may also be prescribed for other conditions as determined by your doctor.

How does CLINDAPENE Gel work?

  • Adapalene is a retinoid-like compound which
    • penetrates deep inside the skin pores and prevents the build-up of dead skin and sebum that leads to acne formation;
    • blocks the hardening processes of the outer skin layer which helps in shedding of old hardened skin cells, thereby promoting growth of new skin cells;
    • blocks the inflammatory reaction, which help to reduce soreness and irritation of skin.
  • Clindamycin belongs to lincomycin group of antibiotics. Clindamycin blocks protein synthesis in the bacteria which are responsible for causing infection of acne affected skin, thus killing the bacteria.

Combination of Adapalene with Clindamycin additively promotes healing of acne lesions and prevents formation of new lesions with clearing up of bacterial infections.

How to use CLINDAPENE Gel?

  • The application of topical gel of CLINDAPENE Gel depends on medical condition of an individual. Apply CLINDAPENE Gel gel as prescribed by your doctor.
  • Apply CLINDAPENE Gel at night before going to bed. Wash the area to be applied with water thoroughly. Make sure the skin is clean and dry before applying the medicine.
  • Take a thin film of CLINDAPENE Gel gel on your fingertip and apply on the affected area gently.
  • Wash your hands properly after applying CLINDAPENE Gel gel.
  • Avoid application of CLINDAPENE Gel into eyes or lips.
  • Do not apply CLINDAPENE Gel on cuts, abrasion or eczematous skin.
  • CLINDAPENE Gel is not to be used in adolescent and children below 12 years of age.
  • Do not discontinue CLINDAPENE Gel without doctor’s advice.
  • If you miss a dose of CLINDAPENE Gel gel, please apply it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for the missed dose.

If you have used more CLINDAPENE Gel gel than advised by your doctor or have accidentally swallowed CLINDAPENE Gel gel, please contact your doctor immediately.

Symptoms of excess use of CLINDAPENE Gel on skin are:

  • Skin irritation
  • Redness of skin
  • Peeling of skin
  • Discomfort on skin

What are the drugs that interact with CLINDAPENE Gel?

Drugs that interact with CLINDAPENE Gel:

  • Aromatic and Alcoholic agents
  • Astringents
  • Peeling agents
  • Skin abrasive cleaners
  • Skin drying agents

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of CLINDAPENE Gel?

Most common side effects of CLINDAPENE Gel are:

  • Dry skin
  • Irritation of the skin
  • Burning sensation of the skin
  • Redness of the skin (erythema)

Please stop application of CLINDAPENE Gel gel and contact your physician immediately if you have

  • irritant contact dermatitis (blistering, cracking skin, swelling, stiffness of skin, ulcers on skin, sore skin forming crust);
  • skin discomfort, pain and swelling of skin;
  • sunburn;
  • itching of the skin;
  • peeling skin;
  • irritation, redness, itching or swelling of the eyelids;
  • flare up of acne.

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking CLINDAPENE Gel?

  • Seek doctor’s advice before taking any other drug or herbal products while on CLINDAPENE Gel.
  • If you are using other medications for acne like benzoyl peroxide, erythromycin or clindamycin, they may be applied in the morning and CLINDAPENE Gel may be applied at night time.
  • If you have a hypersensitivity skin reaction, please stop using CLINDAPENE Gel gel immediately.
  • If you have applied CLINDAPENE Gel gel by mistake into eyes, mouth, nostrils or mucous membrane, wash immediately with warm water.

You are advised not to take CLINDAPENE Gel if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking CLINDAPENE Gel?

Tell your doctor if

  • you are allergic to CLINDAPENE Gel or to any ingredients of this medicine.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you have a history of regional enteritis or ulcerative colitis.
  • you have a history of antibiotic-associated colitis.
  • you are planning a surgery or any procedure.
  • you are pregnant or trying to conceive or are breastfeeding.

What should you do when you have used more CLINDAPENE Gel gel?

If you have used more CLINDAPENE Gel gel than advised by your doctor or have accidentally swallowed CLINDAPENE Gel gel, please contact your doctor immediately.

Symptoms of excess use of CLINDAPENE Gel on skin are:

  • Skin irritation
  • Redness of skin
  • Peeling of skin
  • Discomfort on skin

Frequently Asked questions about CLINDAPENE Gel

  1. How should CLINDAPENE Gel be stored?
  2. CLINDAPENE Gel should be stored below 25° C in a cool, dry place. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

  3. Should I follow any special dietary instructions while using CLINDAPENE Gel gel?
  4. There are no dietary restrictions if you are using CLINDAPENE Gel gel.

  5. How long will it take for CLINDAPENE Gel to work?
  6. It may take 4 to 8 weeks for CLINDAPENE Gel gel to work. Please consult your doctor for more information.

  7. Can I go out in the sun while applying CLINDAPENE Gel?
  8. If possible, limit your sun exposure. If you are going outside, apply sunscreen as advised by your doctor. If you are using CLINDAPENE Gel in the morning, then let is dry first and then apply the sunscreen.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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