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INTRODUCTION

CLAVREST DRY SYRUP is combination of Amoxicillin and Clavulanic Acid which belongs to the group of medicines called Antibiotics. It is used to treat bacterial infections such as middle ear & sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin & soft tissue infections such as dental infections, bone & joint infections, septic abortion (any abortion complicated by uterine infection), and abdominal infections. The symptoms of bacterial infection may include fever, difficulty in breathing, pus formation, and pain.

Do not take CLAVREST DRY SYRUP if you are history of hypersensitivity to beta-lactams, including penicillin and cephalosporins, or any other ingredients of this medicine. CLAVREST DRY SYRUP is not recommended for use if you have if you have history of amoxicillin-clavulanate-associated jaundice/hepatic dysfunction.

Before taking CLAVREST DRY SYRUP, inform your doctor if you are suffering from hepatic or renal impairment. CLAVREST DRY SYRUP should be used with caution in pregnant women only if it is considered clearly necessary. CLAVREST DRY SYRUP should be used with caution in breastfeeding women. CLAVREST DRY SYRUP should be used with caution in children (aged below 12 years) and elderly patients (above 50 years). Consult your doctor before taking CLAVREST DRY SYRUP.

The common side effects associated with the use of CLAVREST DRY SYRUP are diarrhoea, thrush (fungal infection in vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptom worsens.

USES OF CLAVREST DRY SYRUP

It is used for treating the bacterial infections such as:

  • middle ear & sinus infections
  • respiratory tract infections
  • genital tract infections
  • urinary tract infections
  • skin & soft tissue infections such as dental infections
  • bone & joint infections
  • septic abortion (any abortion complicated by uterine infection)
  • abdominal infections

HOW CLAVREST DRY SYRUP WORKS

CLAVREST DRY SYRUP helps in treating bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of an integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby preventing the inactivation of amoxicillin.

DIRECTIONS FOR USE

Syrup/ Oral Suspension

Take CLAVREST DRY SYRUP as advised by your physician. Shake well before use. Use the dosing syringe, cup, or spoon supplied with the pack to measure the dose accurately. A dosing syringe is recommended to dose to a child below 3 months accurately. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Dry Syrup/Dry Suspension 

Take CLAVREST DRY SYRUP as advised by your physician. Open the sachet, reconstitute the dry powder thoroughly in a glass of water, and swallow the mixture immediately. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF CLAVREST DRY SYRUP

COMMON

  • diarrhoea
  • thrush (fungal infection in vagina, skin folds, or mouth)
  • nausea
  • vomiting

UNCOMMON

  • dizziness
  • headache
  • indigestion
  • skin rash
  • itching
  • bumpy itchy rash (hives)

RARE

  • erythema multiforme (a skin rash that looks like small targets)
  • reversible leucopoenia including neutropenia (deficiency of white blood cells)
  • reversible thrombocytopenia (deficiency of blood platelets)

Stop taking CLAVREST DRY SYRUP and contact your doctor if you experience any of the following side effects:   

  • signs of allergic reactions on skin such as skin rash
  • signs of vasculitis (inflammation of blood vessels) such as raised red or purple spots on the skin
  • signs of allergic reactions such as fever, joint pain, swollen glands in the neck, armpit or groin
  • signs of angioedema such as swelling on face or mouth resulting in difficulty in breathing, or collapse
  • erythema multiforme (a skin rash that looks like small targets)
  • Stevens-Johnson syndrome (widespread rash with blistering and skin peeling)
  • exanthemous pustulosis (widespread red rash with blisters containing pus)
  • bullous exfoliative dermatitis (itchy, red, scaly rash with bumps & blisters)
  • signs of drug reaction with eosinophilia and systemic symptoms such as flu-like symptoms, rashes, fever, and swelling in glands
  • inflammation of the liver (hepatitis)
  • jaundice
  • severe diarrhoea

HOW TO MANAGE SIDE EFFECTS

Diarrhoea

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhoea and consult your doctor if the symptom gets worse.

Nausea and vomiting

Try to take CLAVREST DRY SYRUP with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

CLAVREST DRY SYRUP should be used with caution in pregnant women only if it is considered clearly necessary. Consult your doctor before taking.

BREASTFEEDING

CLAVREST DRY SYRUP should be used with caution in breastfeeding women. Consult your doctor before taking it.

KIDNEY

CLAVREST DRY SYRUP should be used with caution in patients with renal impairment. Consult your doctor before taking it.

LIVER

CLAVREST DRY SYRUP is not recommended for use if you have if you have history of amoxicillin-clavulanate-associated jaundice/hepatic dysfunction. It should be used with caution in patients with hepatic impairment. Consult your doctor before taking it.

ALLERGY

Do not take CLAVREST DRY SYRUP if you are history of hypersensitivity to beta-lactams, including penicillin’s and cephalosporins, or any other ingredients of this medicine. Consult your doctor before taking it.

OTHERS

Use in Paediatrics

CLAVREST DRY SYRUP should be used with caution in children (below 12 years). Consult your doctor before taking it.

Use in Geriatrics

CLAVREST DRY SYRUP should be used with caution in elderly patients (above 50 years). Consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interactions

Before taking CLAVREST DRY SYRUP, inform your doctor, if you are taking any of the following medicine:

  • medicine used to treat gout Ex. allopurinol, probenecid
  • medicine used to delay blood clotting Ex. warfarin, acenocoumarol
  • mycophenolate mofetil (a medicine used to prevent the organ rejection after organ transplant)
  • contraceptives (medicines used to prevent conception) Ex. oestrogen

Overdosage:

If you or anyone else accidentally takes too much of CLAVREST DRY SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation), fluid & electrolyte disturbance, and amoxicillin crystalluria which may lead to renal failure in some cases.

SYNOPSIS

Drug :   Amoxicillin, Clavulanic Acid
Pharmacological Category :   Antibiotics
Therapeutic Indication :   Bacterial infections
Dosage Forms :   Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Drops, Injections

MORE INFORMATION

  • Keep the medicine out of sight and reach from children
  • Store CLAVREST DRY SYRUP at a temperature not exceeding 25°C (77°F)

FAQs ABOUT CLAVREST DRY SYRUP

What CLAVREST DRY SYRUP is used for?

CLAVREST DRY SYRUP is used for treating bacterial infections including middle ear & sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin & soft tissue infections such as dental infections, bone & joint infections, septic abortion (any abortion complicated by uterine infection), and abdominal infections.

What happens if you take more CLAVREST DRY SYRUP than your required dose?

If you or anyone else accidentally takes too much of CLAVREST DRY SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation), fluid & electrolyte disturbance, and amoxicillin crystalluria which may lead to renal failure in some cases.

What side effects are seen with CLAVREST DRY SYRUP?

The common side effects associated with the use of CLAVREST DRY SYRUP are diarrhoea, thrush (fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.

Who should avoid taking CLAVREST DRY SYRUP?

Do not take CLAVREST DRY SYRUP if you are a history of hypersensitivity to beta-lactams, including penicillin and cephalosporins, or any other ingredients of this medicine. It is not recommended for use if you have a history of amoxicillin-clavulanate-associated jaundice/hepatic dysfunction.

Is CLAVREST DRY SYRUP safe to use in children?

CLAVREST DRY SYRUP should be used with caution in children (below 12 years). For administering suspensions to children (below 3 months), a graduated syringe is used to dispense the accurate volume. For administering this medicine to children (aged 2 years or below), suspensions should be diluted to half-strength with water. Consult your doctor before taking it.

How does CLAVREST DRY SYRUP work?

CLAVREST DRY SYRUP helps in treating bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of an integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby preventing the inactivation of amoxicillin.

What is the method of taking CLAVREST DRY SYRUP?

Syrup/ Oral Suspension

Take CLAVREST DRY SYRUP as advised by your physician. Shake well before use. Use the dosing syringe, cup, or spoon supplied with the pack to measure the dose accurately. A dosing syringe is recommended to dose children below 3 months accurately. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Dry Syrup/Dry Suspension 

Take CLAVREST DRY SYRUP as advised by your physician. Open the sachet, reconstitute the dry powder thoroughly in a glass of water, and swallow the mixture immediately. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

What if I forget to take CLAVREST DRY SYRUP dose?

If you forgot to take CLAVREST DRY SYRUP dose, take it as early as possible. Do not take a double dose to compensate for the missed dose. Consult your doctor before taking it if you are not sure what to do.

When to stop taking CLAVREST DRY SYRUP?

Do not stop taking CLAVREST DRY SYRUP without thoroughly discussing it with your doctor until the treatment course is completed, even if you start feeling better. This is because if some bacteria survive due to incomplete medication, they may relapse into the infection.

Is CLAVREST DRY SYRUP safe to use in liver patients?

CLAVREST DRY SYRUP is not recommended for use if you have a history of amoxicillin-clavulanate-associated jaundice/hepatic dysfunction. It should be used with caution in patients with hepatic impairment. Consult your doctor before taking CLAVREST DRY SYRUP.

REFERENCES

1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 723.

2. Justin Evans, Maryam Hannoodee, Micah Wittler. Amoxicillin Clavulanate. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. December 2021. [Assessed on 26th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK538164/

3. GSK group of companies. Augmentin. [Revised in December 2017] [Assessed on 27th October 2022] https://gskpro.com/content/dam/global/hcpportal/en_MU/PI/Clavulin-228.5mg5ml-Susp-GDS-24.pdf

4. Micro Labs Ltd. Erox CV 228.5 Dry Syrup. [Assessed on 27th October 2022] http://www.microlabsltd.com/elibrary/node/2170

5 Micro Labs Ltd. Erox CV 457 Dry Syrup. [Assessed on 27th October 2022] http://www.microlabsltd.com/elibrary/node/2181

6. Geno Pharmaceuticals Pvt. Ltd. Genomox-CV. [Assessed on 27th October 2022] https://genopharma.com/pharma/

USEFUL DIAGNOSTIC TESTS

  • blood tests
  • urine tests
  • liver function test

PRODUCT DETAILS

    Net Qty
    1 N
    Hsn Code
    30041090
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

CLAVREST Dry Syrup 30ml

CLAVREST Dry Syrup 30ml Mkt: AAROHI PHARMACEUTICALS LTD

M.R.P.: Rs.67.20
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