INTRODUCTION

CLAGLID 40MG contains Gliclazide which is one of a group of medicines called sulfonylureas that are used to lower the blood sugar level. Gliclazide are used to treat maturity onset diabetes in patients that is not controlled by diet alone. They are not for use in children or in patients with diabetes requiring insulin.

It is used to treat type 2 diabetes. Type 2 diabetes is an illness where the body does not make enough insulin, or the insulin that's made does not work properly. This causes high blood sugar (hyperglycaemia). Your doctor will prescribe your dose depends on your condition and blood sugar levels. CLAGLID 40MG may be taken with or without food. You should not stop taking this medicine without consulting your doctor.

Before taking this medicine, consult your doctor for advice if you have liver, kidney, heart disease or any other medical condition. Do not drive or operate any machines while taking CLAGLID 40MG if your blood sugar is too low or high. The most common side effects are nausea, vomiting, abdominal pain or discomfort, diarrhoea and constipation.

USES OF CLAGLID 40MG

• reduce the blood sugar level in type 2 diabetes

HOW CLAGLID 40MG WORKS

Insulin is the hormone which controls the level of sugar in your blood. CLAGLID 40MG works by increasing the amount of insulin produced by the pancreas.

DIRECTIONS FOR USE

Always take this medicine as your doctor has told you. Swallow the medicine whole with water. Do not chew the medicine.

SIDE EFFECTS OF CLAGLID 40MG

HOW TO MANAGE SIDE EFFECTS

Skin redness:

Avoid hot showers or baths because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.

Constipation:

Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Diarrhoea:

Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• insulin or any other anti-diabetic medicine
• sulphonylureas e.g. glimepiride or glipizide used to treat diabetes
• rifampicin antibiotic used to treat tuberculosis
• carbamazepine, phenobarbital or phenytoin used to treat epilepsy
• medicines which is used to prevent blood clotting (e.g. warfarin)
• cimetidine (used to treat stomach ulcers)
• clofibrate (used to treat high cholesterol in the blood)
• disopyramide (for irregular heartbeats)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT CLAGLID 40MG

How should I take CLAGLID 40MG?

Always take this medicine exactly as your doctor has told you. It can be taken with or without food.

Is it safe to consume alcohol while taking this medicine?

Consumption of alcohol is not recommended during treatment with CLAGLID 40MG due to the increased risk of severe adverse effects.

REFERENCES

1. Gijs W. D. Landman,  Geertruide H. de Bock,  Kornelis J. J. van Hateren, Peter R. van Dijk, Klaas H. Groenier,  Rijk O. B. Gans, Sebastiaan T. Houweling, 1 Henk J. G. Bilo, and Nanne Kleefstra ; Safety and Efficacy of Gliclazide as Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Trials; [Published on 2014] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922704/

2. D B Campbell, R Lavielle, C Nathan; The mode of action and clinical pharmacology of gliclazide: a review; [Published on 1991] https://pubmed.ncbi.nlm.nih.gov/1794262/

3. K.D.Tripathi, Essentials of medical pharmacology, Hormones and related drugs Chapter 19 - Insulin, Oral hypoglycaemic drugs and glucagon, Page – 272.

4. Accord, Barnstaple, EX32 8NS, UK; Electronic Medicines Compendium (EMC); [Revised on 11/2019] [Accessed 29 Sep 2020] https://www.medicines.org.uk/emc/files/pil.5883.pdf

USEFUL DIAGNOSTIC TESTS

• Glucose - Fasting Blood
• Glucose - Postprandial Blood
• Glycosylated Hemoglobin