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Cladoxim 200/125mg Tablet 10'S
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INTRODUCTION
CLADOXIM 200/125MG TABLET is a combination of Cefpodoxime and Clavulanic Acid which belongs to the group of medicines called Cephalosporins and Beta-lactamase inhibitors, respectively. CLADOXIM 200/125MG TABLET is used to treat mild to moderate infections caused by susceptible strains of microorganisms in conditions such as acute otitis media (middle ear infection), pharyngitis (sore throat)/tonsillitis (inflammation of tonsils), community-acquired pneumonia, chronic bronchitis (respiratory infection), and acute maxillary sinusitis (sinus infection) in affected individuals.
CLADOXIM 200/125MG TABLET is also used to treat uncomplicated skin structure infections, urethral and cervical gonorrhoea (sexually transmitted disease), anorectal (anal/rectal) infections, and urinary tract infections in affected individuals.
CLADOXIM 200/125MG TABLET is not recommended for use in patients allergic to Cefpodoxime, Clavulanic Acid, and/or other cephalosporin group of antibiotics. It is also not recommended for use in patients suffering from galactose intolerance, Lapp lactase deficiency (lactose intolerance), and glucose-galactose malabsorption (condition marked by inability of the body to absorb glucose and galactose sugars).
Before taking CLADOXIM 200/125MG TABLET, inform your doctor if you have previous history of hypersensitivity reactions to medicines such as cefpodoxime, other cephalosporins, penicillin, and/or have kidney problems (such as mild/moderate/severe renal impairment), and liver problems (such as hepatic insufficiency/impairment).
CLADOXIM 200/125MG TABLET should be used with caution in pregnant women only if it is clearly necessary. It is not recommended for use in breastfeeding women as it may pass through breastmilk.
CLADOXIM 200/125MG TABLET is indicated for use in children and adolescents (aged above 12 years). Consult your doctor before administering the medicine to infants (less than 2 years) as safety and efficacy of the medicine have not been established. The medicine should be used with caution in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of taking CLADOXIM 200/125MG TABLET are diarrhoea, nausea, vomiting, abdominal pain, headache, vaginal fungal infections, and/or vulvovaginal infections. Consult your doctor if any of these symptoms worsens.
USES OF CLADOXIM 200/125MG TABLET
- Treats mild to moderate infections such as acute otitis media, pharyngitis/tonsillitis, community-acquired pneumonia, chronic bronchitis, and acute maxillary sinusitis in affected individuals
- Treats uncomplicated skin structure infections, urethral and cervical gonorrhoea (sexually transmitted disease), anorectal infections, and urinary tract infections in affected individuals
HOW CLADOXIM 200/125MG TABLET WORKS
CLADOXIM 200/125MG TABLET helps to treat mild to moderate infections, where Cefpodoxime works by preventing the formation of the protective covering of the bacteria which is essential for the survival of bacteria and Clavulanic Acid works by reducing the resistance and enhancing the activity of Cefpodoxime against bacteria thus preventing the occurrence of infections in affected individuals.
DIRECTIONS FOR USE
Tablet:
Take CLADOXIM 200/125MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF CLADOXIM 200/125MG TABLET
COMMON
- diarrhoea, nausea, vomiting, abdominal pain
- headache
- vaginal fungal infections, vulvovaginal infections
UNCOMMON
- fungal/yeast infection, bacterial infections, parasitic infections
- inflammation of stomach, abdominal distention
- general discomfort, weakness, tiredness
- fever, chest pain, back pain, muscle pain, chills, gout, localized/generalized pain, abscess, allergic reaction, facial swelling
- congestive heart failure, racing heartbeats, vasodilation (widening of blood vessels), high/low blood pressure
- indigestion, anorexia (eating disorder), belch, decreased appetite, flatulence, constipation, mouth ulcers, gastrointestinal disorders, rectal disorders, dehydration, swelling in legs/arms, weight increased, liver damage
- dry mouth, tongue disorders, increased thirst, oral lesions, dry throat, toothache, gastric pressure.
- anaemia
- dizziness, sleeplessness, excessive sleepiness, anxiety, shakiness, nervousness, change in dreams, impaired concentration, confusion, nightmares, tingling/prickling sensation, internal spinning sensation
- asthma, cough, bleeding from nose, stuffy nose, wheezing, shortness of breath, pleural effusion, pneumonia, sinusitis (sinus infection)
- red itchy welts, rash, itching at non-application site, fungal dermatitis, dry skin at non-application site, hair loss, sunburn, hypersensitivity mucocutaneous reaction
- taste alterations, eye irritation, taste loss, ringing in ears
- metrorrhagia (abnormal bleeding), pain while urinating, frequent urination at night, penile infection, vaginal pain
- anaphylactic reactions (life threatening allergic reaction), bronchospasm (tightening of airways), purpura (rash of purple spots) and angioedema (swelling underneath the skin)
RARE
Stop taking CLADOXIM 200/125MG TABLET and inform your doctor straight away if you experience any of the following side effects:
- signs of allergic reactions such as runny nose, sneezing, breathlessness, itchy skin, and/or raised rash
- seizures
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.
Headache
If CLADOXIM 200/125MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking CLADOXIM 200/125MG TABLET. If it lasts more than a week or severe, inform your doctor.
Nausea And Vomiting
Try to take CLADOXIM 200/125MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredCLADOXIM 200/125MG TABLET should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before taking CLADOXIM 200/125MG TABLET.
BREASTFEEDING
ContraindicatedCLADOXIM 200/125MG TABLET is not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking CLADOXIM 200/125MG TABLET.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate machines if you feel dizzy after taking CLADOXIM 200/125MG TABLET.
KIDNEY
Use with CautionCLADOXIM 200/125MG TABLET should be used with caution in patients with kidney problems such as mild, moderate, and severe renal impairment. Consult your doctor before taking CLADOXIM 200/125MG TABLET.
LIVER
Use with CautionCLADOXIM 200/125MG TABLET should be used with caution in patients with liver problems such as hepatic impairment/insufficiency. Consult your doctor before taking CLADOXIM 200/125MG TABLET.
ALLERGY
ContraindicatedDo not take CLADOXIM 200/125MG TABLET if you are allergic to Cefpodoxime, Clavulanic Acid, other cephalosporin group of antibiotics, and/or any other ingredients of this medicine.
OTHERS
CLADOXIM 200/125MG TABLET is not recommended for use if you:
- galactose intolerance, Lapp lactase deficiency (lactose intolerance), glucose-galactose malabsorption (condition marked by inability of the body to absorb glucose and galactose sugars)
Before taking CLADOXIM 200/125MG TABLET inform your doctor if you have:
- previous hypersensitivity reactions to cefpodoxime, other cephalosporins, penicillin, and/or other medicines
Use in Paediatrics:
CLADOXIM 200/125MG TABLET is recommended for use in children and adolescents (aged above 12 years). Consult your doctor before administering the medicine to infants (less than 2 years) as safety and efficacy of the medicine have not been established.
Use in Geriatrics:
CLADOXIM 200/125MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking CLADOXIM 200/125MG TABLET.
INTERACTIONS
A. Drug-Drug Interactions:
Before taking CLADOXIM 200/125MG TABLET, inform your doctor, if you are taking any of the following medicine:
- antacids (medicines used to relieve indigestion and heartburn) Ex. sodium bicarbonate, aluminium hydroxide
- probenecid (used to treat gout)
- nephrotoxic drugs (medicines that can damage kidney via various mechanisms) Ex. aminoglycosides, amphotericin B
Overdosage:
If you or anyone else accidentally take too much of CLADOXIM 200/125MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CLADOXIM 200/125MG TABLET may include nausea, vomiting, epigastric distress, and/or diarrhoea.
SYNOPSIS
| Drug | : | Cefpodoxime, Clavulanic Acid |
| Pharmacological Category | : | Cephalosporin, Beta-lactamase inhibitors |
| Therapeutic Indication | : | Mild to moderate infections (caused by susceptible strains of microorganisms) |
| Dosage Forms | : | Tablet, Dispersible Tablet, Dry Syrup, Dry Suspension, Oral Suspension, Suspension, Syrup |
MORE INFORMATION
- Keep CLADOXIM 200/125MG TABLET out of reach of children
- Store at room temperature in a cool and dry place
FAQs ABOUT CLADOXIM 200/125MG TABLET
Q. What is CLADOXIM 200/125MG TABLET and why is it prescribed?
A. CLADOXIM 200/125MG TABLET is a combination of Cefpodoxime and Clavulanic Acid which belongs to the group of medicines called Cephalosporins and Beta-lactamase inhibitors, respectively. It is used to treat mild to moderate infections caused by susceptible strains of microorganisms in conditions such as acute otitis media (middle ear infection), pharyngitis (sore throat)/tonsillitis (inflammation of tonsils), and community-acquired pneumonia. It is also used to treat uncomplicated skin structure infections, urethral and cervical gonorrhoea (sexually transmitted disease), anorectal (anal/rectal) infections, and urinary tract infections in affected individuals.
Q. How CLADOXIM 200/125MG TABLET works?
A. CLADOXIM 200/125MG TABLET helps to treat mild to moderate infections, where Cefpodoxime works by preventing the formation of the protective covering of the bacteria which is essential for the survival of bacteria and Clavulanic Acid works by reducing the resistance and enhancing the activity of Cefpodoxime against bacteria thus preventing the occurrence of infections in affected individuals.
Q. What are the most common side effects of taking CLADOXIM 200/125MG TABLET?
A. The most common side effects of taking CLADOXIM 200/125MG TABLET are diarrhoea, nausea, vomiting, abdominal pain, headache, vaginal fungal infections, and/or vulvovaginal infections. Consult your doctor if any of these symptoms worsens.
Q. Can CLADOXIM 200/125MG TABLET cause diarrhoea?
A. Yes, CLADOXIM 200/125MG TABLET causes diarrhoea as it is the most common side effect associated with the use of medicine. If such side effects experienced, then drink plenty of water and stay hydrated. Avoid taking any medicine on your own to treat diarrhea. Consult and inform your doctor if the symptom gets worse.
Q. Can CLADOXIM 200/125MG TABLET be used in pregnant and breastfeeding women?
A. Yes, CLADOXIM 200/125MG TABLET can be used but with caution in pregnant women only if clearly necessary. It is not recommended for use in breastfeeding women since it passes through breast milk. Consult your doctor before taking CLADOXIM 200/125MG TABLET.
REFERENCES
1. K.D. Tripathi. Beta-Lactam Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 724 & 728.
2. Angela Giarratano, Samantha EL Green, and David P Nicolau. Review of antimicrobial use and considerations in the elderly population. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in May 2017] [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909780/
3. CiplaMed. CEFOPROX CV Tablets. [Revised in October 2018] [Accessed on 7th July 2022] https://ciplamed.com/content/cefoprox-cv-tablets-suspension
4. Incepta Pharmaceuticals Ltd. Duo-5 LS. [Accessed on 7th July 2022] http://www.inceptapharma.com/product-details.php?pid=506
5. Macleods Pharmaceuticals Ltd. ZEDOCEF CV 50 DT. [Accessed on 7th July 2022] https://www.macleodspharma.com/products/
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Bacterial culture test
AUTHOR DETAILS
Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 30 Jan 2023 | 04:53 PM(IST)
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