Check Availability & Expiry
INTRODUCTION
CIPROBID INFUSION contains ciprofloxacin, which belongs to the group of medicines called fluoroquinolone antibiotics. It is used in the treatment of bacterial infections such as respiratory tract infections, recurring ear and acute sinus infections, urinary tract infections, genital tract infections, intra-abdominal infections, gastrointestinal tract infections, skin and soft tissue infections, bones or joint infection and anthrax, etc.
Before receiving CIPROBID INFUSION, inform your doctor if you are having kidney problems, neurological conditions, or heart diseases such as a tear in the aortic wall of the heart, bulge or large blood vessels, leaking in the heart valves and congenital heart disease or myasthenia gravis. CIPROBID INFUSION should preferably be avoided during pregnancy and breastfeeding. CIPROBID INFUSION should be used with caution in elderly patients.
The most common side effects of receiving CIPROBID INFUSION are reactions at the injection site, nausea, vomiting and diarrhea. Consult a doctor immediately if any of the symptoms worsen.
USES OF CIPROBID INFUSION
CIPROBID INFUSION is used in adults to treat bacterial infections of the following:
- respiratory tract infections
- recurring ear and sinusitis infections
- urinary tract infections
- genital tract infections
- gastrointestinal tract infections
- intraabdominal infections
- skin and soft tissue infections
- bone and joint infections
- management for fever in neutropenia-associated infection
CIPROBID INFUSION is used in children and adolescents to treat the following:
- lung and bronchial infections with cystic fibrosis
- complicated urinary tract infections, including infections that have reached the kidneys (pyelonephritis)
CIPROBID INFUSION is used in the treatment of anthrax inhalation exposure in both children and adults.
HOW CIPROBID INFUSION WORKS
[GBNKEYWOED] is an antibacterial agent that acts by preventing bacterial replication by targeting the essential enzyme inside the bacteria. This leads to the restriction of growth of the disease-causing bacteria inside the infected person and thereby CIPROBID INFUSION helps to control the infection and treat its symptoms caused by it.
DIRECTIONS FOR USE
CIPROBID INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF CIPROBID INFUSION
COMMON
- nausea, diarrhoea, vomiting
- joint pain and joint inflammation in children
- reaction at the injection site
- skin rash
- temporary increase in the level of substances in the blood (transaminases)
UNCOMMON
- joint pain
- fungal superinfections (severe fungal infections)
- high concentration of eosinophils (type of white blood cell)
- increase or decrease in amounts of blood clotting factor (thrombocytes)
- loss of appetite
- hyperactivity, agitation, confusion, disorientation, hallucinations
- headache, dizziness, sleeping problems
- pins and needles, taste disorders
- unusual sensitivity to stimuli of senses (Hyperesthesia)
- giddiness, seizures
- eyesight problems including double vision
- loss of hearing
- rapid heartbeat (tachycardia)
- expansion of blood vessels (vasodilation)
- low blood pressure
- abdominal pain
- digestive problems such as stomach upset, indigestion, heartburn, and wind
- liver disorders, increased amount of bilirubin in blood
- jaundice (cholestatic icterus)
- itching, hives
- poor kidney function, kidney failure
- pains in your muscles and bones, feeling unwell (asthenia)
- fever, fluid retention
- increase in blood alkaline phosphatase (a certain substance in blood)
RARE
- muscle pain, inflammation of the joints, increased muscle tone and cramping
- inflammation of the bowel (colitis) due to antibiotic use
- changes in the blood count (leukopenia, leucocytosis, neutropenia, anaemia)
- drop in number of red blood cells, white blood cells and platelets (pancytopenia)
- bone-marrow depression
- allergic reaction, swelling (oedema)
- rapid swelling of the skin and mucous membranes (angioedema)
- increased blood sugar level (hyperglycaemia)
- decreased blood sugar level (hypoglycaemia)
- anxiety reaction, strange dreams, depression
- mental disturbances (psychotic reactions leading to suicidal thoughts, suicidal attempts, or completed suicide)
- decreased skin sensitivity, tremor, migraine, disorder of sense of smell (olfactory disorders)
- tinnitus, impaired hearing, fainting
- inflammation of the blood vessel (vasculitis)
- shortness of breath including asthmatic symptoms
- pancreatitis, hepatitis, death of liver cells (liver necrosis)
- sensitivity to light, pin-point bleeding under the skin (petechiae)
- blood or crystals in urine, urinary tract inflammation
- excessive sweating
- increased levels of enzyme amylase
- Pain and swelling in the joints, and inflammation or rupture of tendons
- nerve damage (neuropathy) such as pain, burning sensation, tingling, numbness, and weakness especially in the feet and legs or hands and arms
Stop receiving CIPROBID INFUSION and inform your doctor immediately if you experience any of the following side effects
- severe allergic reaction with symptoms such as tightness in the chest, feeling dizzy, feeling sick, faint, and experience dizziness while standing
- severe pain in your abdomen, chest or back, which can be symptoms of an aortic aneurysm and dissection
- sudden shortness of breath, especially when lying down flat
- swelling of ankles, feet, or abdomen,
- rapid irregular heartbeat
- cerebral ischemia (low blood flow to the brain) or stroke, seizure (fits)
- impairment of the eyesight
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Medicine must be preferably received just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy foods.
Diarrhoea:
Keep yourself hydrated by drinking lots of fluids, such as coconut water or fruit. Do not take any medicine on your own without your doctor’s opinion as it may interact with the medicine you have received. Inform your doctor if the loose motions do not stop or worsen with time.
Skin rash:
Apply calamine lotion or aloe vera to calm your skin. Try to avoid having hot showers/baths as it can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors and apply sunscreen. Regularly moisturize your skin.
WARNING & PRECAUTIONS
PREGNANCY
CIPROBID INFUSION is generally not recommended for use in pregnant women. Consult your doctor before receiving CIPROBID INFUSION.
BREASTFEEDING
CIPROBID INFUSION is generally not recommended for use in breastfeeding women as it may pass through breast milk and could be harmful to the baby. Consult your doctor before receiving CIPROBID INFUSION.
DRIVING AND USING MACHINES
Do not drive or use machinery after receiving CIPROBID INFUSION as the medicine could cause neurological disturbances and can make you less alert. Consult your doctor before receivingCIPROBID INFUSION.
ALCOHOL
Avoid consumption of alcohol while receiving CIPROBID INFUSION because it can make you dizzier.
KIDNEY
CIPROBID INFUSION should be given with caution in patients with severe kidney problems. Consult your doctor before receiving CIPROBID INFUSION.
LIVER
CIPROBID INFUSION is not recommended in patients with liver damage. Consult your doctor before receiving CIPROBID INFUSION.
ALLERGY
Do not receive CIPROBID INFUSION if you are allergic to ciprofloxacin or other quinolone antibiotics or to any other ingredients in this medicine.
HEART DISEASE
CIPROBID INFUSION should be given with caution in patients suffering from heart problems such as prolonged QT interval (seen on ECG, electrical recording of the heart), having very slow heart rhythm (bradycardia), weak heart (heart failure), history of heart attack, leaking of heart valves, tearing in the aortic wall, bulging of a large blood vessel, and congenital heart valve disease. Consult your doctor before receiving CIPROBID INFUSION.
OTHERS
CIPROBID INFUSION is not recommended for use if you suffer from
- fits (epilepsy) or other neurological conditions
- depression or psychosis
Before receiving CIPROBID INFUSION, inform your doctor if you have:
- tendon problems during previous treatment with antibiotics
- a history of diabetes
- a disease that causes muscle weakness (myasthenia gravis)
- a deficiency in glucose-6-phosphate dehydrogenase (G6PD), since it could cause a risk of anaemia
- a history of connective tissue disorder such as Marfan syndrome or Ehlers-Danlos syndrome
- Turner syndrome (chromosomal defect)
- Sjogren’s syndrome (an inflammatory autoimmune disease)
- blood related disorders Ex. Takayasu arteritis, giant cell arteritis
- Behcet’s disease (blood vessel inflammation throughout your body)
- rheumatoid arthritis (autoimmune disease of the joints)
- endocarditis (an infection of the heart)
Use in paediatrics:
CIPROBID INFUSION should be given with caution in children and adolescents (under 18 years of age). Consult before receiving CIPROBID INFUSION.
Use in geriatrics:
CIPROBID INFUSION should be given with caution in elderly patients. Consult your doctor before receiving CIPROBID INFUSION.
INTERACTIONS
A. Drug-Drug interactions:
Before receiving CIPROBID INFUSION, inform your doctor if you are taking any of the following medicine:
- vitamin K antagonists (Ex. warfarin, acenocoumarin, phenprocoumon or fluindione)
- other oral anti-coagulants (medicine used to thin the blood such as warafrin
- probenecid (medicine used to treat gout)
- methotrexate (medicine used to treat certain types of cancer, psoriasis, rheumatoid arthritis)
- theophylline (medicine used for the treatment of breathing problems)
- tizanidine (medicine used to treat muscle spasticity in multiple sclerosis)
- olanzapine, clozapine, risperidone (medicine used to treat psychosis)
- ropinirole (medicine used to treat parkinson’s disease)
- phenytoin (medicine used to treat epilepsy (fits))
- cyclosporin (medicine used to treat skin conditions, rheumatoid arthritis and organ transplantation)
- other medicines that can alter your heart rhythm (Ex. quinidine, hydroquinone, disopyramide, amiodarone, sotalol, dofetilide, ibutilide)
- tricyclic antidepressants (medicine used to treat depression such as amoxapine)
- some antimicrobials (that belong to the group of macrolides such as azithromycin)
- zolpidem (medicine used to treat sleep disorders)
- pentoxifylline (medicine used in the treatment of circulatory disorders)
- caffeine (medicine used to stimulate the central nervous system)
- duloxetine (medicine used to treat depression, diabetic nerve damage or incontinence)
- lidocaine (medicine used to treat heart conditions or anesthetic use)
- sildenafil medicine used to treat erectile dysfunction)
- agomelatine (medicine used to treat depression)
Overdosage:
CIPROBID INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. In case if you experience any unusual symptoms, consult your doctor immediately or visit a nearby hospital.
SYNOPSIS
| Drug | : | Ciprofloxacin |
| Pharmacological Category | : | Fluoroquinolone antibiotics |
| Therapeutic Indication | : | Treat specific kinds of bacterial infections |
| Dosage Forms | : | Injections, infusions, tablets, drops, dry syrup, eye ointment, eye drops, ointment, ear drops |
MORE INFORMATION
- Keep out of reach from children
- Store at room temperature
FAQs ABOUT CIPROBID INFUSION
What is CIPROBID INFUSION used for?
CIPROBID INFUSION contains ciprofloxacin, which is used in the treatment of bacterial infections such as respiratory tract infections, recurring ear and acute sinus infections, urinary tract infections, genital tract infections, intra-abdominal infections, gastrointestinal tract infections, skin and soft tissue infections, bone, and joint infections. CIPROBID INFUSION is also used in the management of fever in neutropenia-associated infection. Use of CIPROBID INFUSION in children and adolescents is to treat lung and bronchial infections with cystic fibrosis, and complicated urinary tract infections, including infections that cause pyelonephritis (kidney infection that needs immediate medical attention). CIPROBID INFUSION is prescribed for both adults and children for anthrax inhalation exposure infections. Consult your doctor before receiving CIPROBID INFUSION.
If I start feeling well, can I skip the dose of CIPROBID INFUSION
No. You should complete the full course of CIPROBID INFUSION as prescribed by your doctor. It is important that CIPROBID INFUSION be taken at the right dose and for the right duration given. Otherwise, the symptoms can prevail and sometimes worsen.
Is CIPROBID INFUSION safe?
CIPROBID INFUSION is a relatively safe drug. However, the complications are more comparable to other drugs and hence should only be strictly taken if prescribed by a doctor in the appropriate dose, frequency, and duration as advised.
Can CIPROBID INFUSION cause diarrhoea?
Yes, the use of CIPROBID INFUSION can cause diarrhoea. It is an antibiotic that eliminates harmful bacteria. However, it also attacks the helpful bacteria in your stomach or intestine and causes diarrhoea. If you are experiencing severe diarrhoea.
Can CIPROBID INFUSION increase the risk of muscle damage?
Yes, the use of CIPROBID INFUSION is known to increase the risk of muscle damage, commonly in the ankle (Achilles tendon). Muscle damage can happen, especially to elderly patients who receive CIPROBID INFUSION. Inform your doctor if you feel any kind of muscle pain while receiving CIPROBID INFUSION.
Can I receive CIPROBID INFUSION for cough and flu?
No, CIPROBID INFUSION is an antibacterial medicine that acts only against specific kinds of bacterial infections and not against viral infections causing cough and flu. You should not self-medicate CIPROBID INFUSION without prior consultation with a doctor. Self-prescription is dangerous and can lower the efficacy and therapeutic outcome of CIPROBID INFUSION leading to antibiotic resistance.
Can I receive CIPROBID INFUSION for longer than the prescribed duration if not recovered?
No, prolonged use of CIPROBID INFUSION can cause an overgrowth of other non-susceptible organisms. Hence, if you do not recover from the infection, inform the doctor and get his advice.
REFERENCES
1. KD Tripathi. Fluoroquinolones antibiotics. Essentials of Medical Pharmacology. Seventh Edition, 2013. Page - 709.
2. Redgrave, Liam S., Sam B. Sutton, Mark A. Webber, and Laura JV Piddock. Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success. Trends in microbiology. 2014. [Accessed on 10th June 2022] https://www.cell.com/trends/microbiology/pdf/S0966-842X(14)00089-4.pdf
3. Aldred KJ, Kerns RJ, Osheroff N. Mechanism of quinolone action and resistance. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2014. [Accessed on 10th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985860/
4. DEMO S.A. PHARMACEUTICAL INDUSTRY. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 10th June 2022] https://www.medicines.org.uk/emc/files/pil.13287.pdf
5. Bayer Corporation. [Revised in April 2017] [Accessed on 10th June 2022] https://s3-us-west-2.amazonaws.com/drugbank/fda_labels/DB00537.pdf?1265922808
6. Pharmacy Retailing (NZ) Limited t/a Healthcare Logistics. [Revised in February 2022] [Accessed on 10th June 2022] https://www.medsafe.govt.nz/profs/Datasheet/a/aspenciprofloxacininj.pdf
7. Bayer HealthCare Pharmaceuticals Inc. U.S. Food & Drug Administration. [Revised in July 2013] [Accessed on 10th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019857s062lbl.pdf
8. Sagent Pharmaceuticals, Inc. [Revised in August 2020] [Accessed on 10th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7049f870-6741-4a67-8033-398c36126a06
9. Axa Parenterals Limited. Ciprofloxacin. [Accessed on 10th June 2022]https://fdaghana.gov.gh/img/pils/Habcip%20200mg_100ml%20Infusion%20(Ciprofloxacin).pdf
10. Pharmacy Retailing (NZ) Limited t/a Healthcare Logistics. [Revised in July 2022] [Accessed on 10th October 2022] https://www.medsafe.govt.nz/profs/Datasheet/a/aspenciprofloxacininj.pdf
11. SAGENT Pharmaceuticals. [Revised in August 2020] [Accessed on 10th October 2022] https://www.sagentpharma.com/wp-content/uploads/2022/02/Ciprofloxacin_PI-MG_August-2020.pdf
12. Baxter Corporation. [Revised in October 2018] [Accessed on 10th October 2022] https://www.baxter.ca/sites/g/files/ebysai1431/files/2018-11/CIPROFLOXACIN_INJECTION_EN_0.pdf
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear
PRODUCT DETAILS
ALTERNATE BRANDS
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
