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Best Price* ₹ 130.38 MRP ₹ 159.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: CELERA HEALTHCARE PVT LTD * Country of Origin: India * Delivery charges if applicable will be applied at checkout


INTRODUCTION

CERENAC GM TABLET contains a combination of Diacerein and Gucosamine sulfate potassium chloride which belongs to the group of medicines called Nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to treat osteoarthritis of the knee.

Osteoarthritis is a type of joint degeneration that occurs when the protective cartilage that cushions the ends of the bones wears down over time and generates symptoms such as stiffness, pain in movement, tenderness, swelling, bone spurs, crackling sound while walking. 

Before taking CERENAC GM TABLET inform your doctor if you have liver, kidney, heart, intestine, abdominal disease, asthma, or suffer from impaired glucose tolerance, or severe issues with the joints. Avoid consumption of alcohol during this treatment as it can increase liver damage.

CERENAC GM TABLET is not recommended for use in pregnant and breastfeeding women. It is not recommended for use in children and adolescents below 18 years of age. CERENAC GM TABLET should be used with caution in the elderly above 65 years of age.

The most common side effects of taking CERENAC GM TABLET are diarrhea, abdominal pain, flatulence, headache, and nausea. Consult your doctor if symptoms do not show improvement.

USES OF CERENAC GM TABLET

  • Treat osteoarthritis of the knee

HOW CERENAC GM TABLET WORKS

CERENAC GM TABLET works by relieving symptoms of osteoarthritis in which diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that plays a role in the development of symptoms of osteoarthritis and glucosamine sulfate potassium chloride delays many inflammation-induced catabolic processes in the cartilage and promotes the formation of cartilage.

DIRECTIONS FOR USE

Take CERENAC GM TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.

SIDE EFFECTS OF CERENAC GM TABLET

COMMON

  • soft stools
  • abdominal pain
  • frequent bowel movements
  • flatulence
  • skin effects such as rash, itching, eczema
  • discoloration of urine
  • headache, tiredness
  • nausea
  • indigestion
  • constipation

UNCOMMON

  • flushing
  • increase in liver enzymes levels in blood tests
  • discoloration of colon mucosa

RARE

Stop taking CERENAC GM TABLET and contact your doctor immediately if you experience any of the following side effects:

  • abdominal pain, jaundice, changes in the color of the urine (from yellow-orange to red or even brown), pigmentation of the intestinal mucosa, reduced consciousness or itching of the skin occur (signs of liver disease)
  • severe diarrhea
  • swollen face, tongue and/or pharynx and/or difficulty swallowing or hives together with difficulties breathing (angioedema)

HOW TO MANAGE SIDE EFFECTS

Bloating

Eat smaller and more frequent meals, and exercise regularly. If the symptom does not show improvement, consult your doctor.

Constipation

Eat lots of fiber-rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not show improvement, consult your doctor.

Diarrhea

Drink lots of water or fruit juice to keep yourself hydrated. If the symptom does not show improvement, consult your doctor.

Headache

Avoid bright lights, drink more water and take a rest. If the symptom does not show improvement, consult your doctor.

Nausea And Vomiting

Stick to simple meals. Avoid eating oily or spicy food. If the symptom does not show improvement, consult your doctor.

Stomach Pain

Eat and drink slowly. Keep a heating pad on your stomach. If the symptom does not show improvement, consult your doctor.

WARNING & PRECAUTIONS

PREGNANCY
Contraindicated

CERENAC GM TABLETis not recommended for use in pregnancy or for women planning to be pregnant. Consult your doctor before taking it.

BREASTFEEDING
Contraindicated

CERENAC GM TABLETis not recommended for use in breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES
Use with Caution

The effect of CERENAC GM TABLET on driving and using machines has not been established yet, however, if you feel dizzy or sleepy abstain from driving.

ALCOHOL
Contraindicated

Do not consume alcohol while taking CERENAC GM TABLET as it can make increase your liver problems.

KIDNEY
Use with Caution

CERENAC GM TABLETshould be used with caution in patients with kidney disease. Consult your doctor before taking it.

LIVER
Consult your doctor

CERENAC GM TABLETis not recommended for use in patients with liver problems. CERENAC GM TABLET should be used with caution in patients with liver disease. Consult your doctor before taking it.

ALLERGY
Contraindicated

Do not take CERENAC GM TABLET if you are allergic to Diacerein or Gucosamine sulfate potassium chloride or any other ingredients of this medicine.

LUNGS
Use with Caution

CERENAC GM TABLET should be used with caution in patients with asthma. Consult your doctor before taking it.

HEART DISEASE
Use with Caution

CERENAC GM TABLET should be used with caution in patients with heart disease. Consult your doctor before taking it.

USE IN PEDIATRICS
Contraindicated

CERENAC GM TABLET is not recommended for use in children and adolescents below 18 years of age.  Consult your doctor before taking it.

USE IN GERIATRICS
Use with Caution

CERENAC GM TABLET should be used with caution in the elderly above 65 years of age as they are more vulnerable to diarrheal problems and other side effects. Consult your doctor before taking it.

OTHERS

CERENAC GM TABLET is not recommended for use if you:

  • are allergic to shellfish, peanuts, soya

Before taking CERENAC GM TABLET, inform your doctor if you:

  • suffer from impaired glucose tolerance
  • have joint swelling, warmth and redness, painfulness, persistent joint stiffness, pain at rest, pain in more than one joint, increased body temperature and decrease in body weight (can be symptoms of rheumatoid arthritis, systemic lupus, gout, tumors)
  • suffer ulcerative colitis or Crohn’s disease
  • suffer from intestinal obstruction or pseudo-obstruction.
  • have abdominal disorders
  • intolerant to certain sugars

INTERACTIONS

A. Drug-Drug interactions:

Before taking CERENAC GM TABLET, inform your doctor if you are taking any of the following medicine:

  • warfarin (a medicine used to thin the blood)
  • medicines for diabetes (Ex. metformin, glipizide)
  • tetracycline (an antibiotic against bacterial infections)
  • antacids (medicines for treating stomach acidity)
  • a diuretic or cardiac glycosides (Ex. digitoxin, digoxin)
  • laxatives (Ex. bisacodyl)

Overdosage:

If you or anyone else accidentally take too much of CERENAC GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are intense diarrhea, dizziness, headache, nausea, vomiting, constipation, and joint pain.

SYNOPSIS

Drug :   Diacerein, Gucosamine
Pharmacological Category :   Anthraquinone, Anti inflammatory
Therapeutic Indication :   Osteoarthritis
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep CERENAC GM TABLET out of reach from children
  • Store at room temperature

FAQs ABOUT CERENAC GM TABLET

Q: What is CERENAC GM TABLET used for?

A: CERENAC GM TABLET is used to treat osteoarthritis of the knee. Osteoarthritis is a type of joint degeneration that occurs when the protective cartilage that cushions the ends of the bones wears down over time and generates symptoms such as stiffness, and pain in movement.

Q: How does CERENAC GM TABLET work?

A: CERENAC GM TABLET works by relieving symptoms of osteoarthritis in which diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that plays a role in the development of symptoms of osteoarthritis and glucosamine sulfate potassium chloride delays many inflammation-induced catabolic processes in the cartilage and promotes the formation of cartilage.

Q: What if I accidentally take more of CERENAC GM TABLET?

A: If you or anyone else accidentally take too much of CERENAC GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are intense diarrhea, dizziness, headache, nausea, vomiting, constipation, and joint pain.

Q: Can CERENAC GM TABLET be used in elderly patients?

A: CERENAC GM TABLETshould be used with caution in the elderly above 65 years of age as they are more vulnerable to diarrheal problems and other side effects. Consult your doctor before taking.

Q: Can CERENAC GM TABLET be used in children?

A: CERENAC GM TABLETis not recommended for use in children and adolescents below 18 years of age.  Consult your doctor before taking this medicine.

REFERENCES

1. KD Tripathi. Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Eighth Edition. 2019. Page –220-224.

2. Jörg Jerosch. Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. [Accessed on 5th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150191/

3. Johanne Martel-Pelletier. Effects of Diacerein at the Molecular Level in the Osteoarthritis Disease Process. [Accessed on 5th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383474/

4. Chanelle Medical. Health Products Regulatory Authority (HPRA). [Revised in May 2016] [Accessed on 5th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/2171814.PA1521_003_003.1a94fbbc-f593-4a32-a58c-5f8f8bb39b75.000001PIL%201500mg.160824.pdf

5. Chanelle Medical. Health Products Regulatory Authority (HPRA). [Revised in May 2016] [Accessed on 5th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/2171814.PA1521_003_002.cb4ba0a2-1887-4c40-afe6-e19cea656342.000001750mg%20PIL%20.160824.pdf

6. TRB PHARMA S.A. Diacerein [Revised in April 2019] [Accessed on 5th August 2022] https://myhealthbox.eu/en/view/3364878/1066595e9806313ef81279755226ab79/leaflet

7. Trima Israel Pharmaceutical Products Maabarot Ltd. Diacerein. [Revised in November 2015] [Accessed on 5th August 2022] https://myhealthbox.eu/en/view/3529427/469334cbb76f29e848cd1e9f1a64d1ac/leaflet

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 24 Feb 2023 | 04:08 PM(IST)

PRODUCT DETAILS

    Country Of Origin
    India
ALTERNATE BRANDS
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.