INTRODUCTION

CEPODEM XP 100 DRY SUSPENSION is a combination of Cefpodoxime and Clavulanic acid which belongs to the group of medicines called Cephalosporins and Beta-lactamase inhibitors, respectively. CEPODEM XP 100 DRY SUSPENSION is used in children to treat mild to moderate infections such as otitis media (middle ear infection), nose & throat infections, respiratory tract infection, urinary tract infection, reproductive tract infection, and skin infection.

CEPODEM XP 100 DRY SUSPENSION is not recommended for use in children allergic to Cefpodoxime, Clavulanic acid, and/or other cephalosporin group of antibiotics. It is also not recommended for use in children suffering from galactose intolerance, Lapp lactase deficiency (lactose intolerance), and glucose-galactose malabsorption (condition marked by body’s inability to absorb glucose and galactose sugars).

Before administering CEPODEM XP 100 DRY SUSPENSION, inform your doctor if the child has previous history of hypersensitivity reactions to medicines such as cefpodoxime, other cephalosporins, penicillin, and/or have kidney problems (such as mild/moderate/severe renal impairment), and liver problems (such as hepatic insufficiency/impairment).

CEPODEM XP 100 DRY SUSPENSION is not recommended for use in pregnant and breastfeeding women since it is used only in children (aged below 12 years). It is also not recommended for use in elderly patients.

CEPODEM XP 100 DRY SUSPENSION is recommended for use in children aged below 12 years. Consult your doctor before administering the medicine to infants (less than 2 years) as safety and efficacy of the medicine have not been established. It is not recommended for use in elderly patients as it is used only in children.

The most common side effects of administering CEPODEM XP 100 DRY SUSPENSION in child are diarrhoea, nausea, vomiting, abdominal pain, headache, vaginal fungal infections, and/or vulvovaginal infections. Consult your doctor if any of these symptoms worsens.

USES OF CEPODEM XP 100 DRY SUSPENSION

Used in paediatric patients:

• To treat mild to moderate infections such as otitis media (middle ear infection), nose & throat infections, respiratory tract infection, urinary tract infection, reproductive tract infection, and skin infection

HOW CEPODEM XP 100 DRY SUSPENSION WORKS

CEPODEM XP 100 DRY SUSPENSION helps to treat mild to moderate infections, where Cefpodoxime works by preventing the formation of the protective covering of the bacteria which is essential for the survival of bacteria and Clavulanic acid works by reducing the resistance and enhancing the activity of Cefpodoxime against bacteria thus preventing the occurrence of infections in affected children.

DIRECTIONS FOR USE

Dry Syrup/ Oral Suspension:

Administer CEPODEM XP 100 DRY SUSPENSION as advised by your physician. Shake the dry powder loose and reconstitute the dry powder in required quantity of water before consuming. Your doctor will decide the exact dose and duration of treatment for your child depending on child’s age, body weight and disease condition.

Syrup:

Administer CEPODEM XP 100 DRY SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the exact dose and duration of treatment for your child depending on child’s age, body weight and disease condition.

SIDE EFFECTS OF CEPODEM XP 100 DRY SUSPENSION

HOW TO MANAGE SIDE EFFECTS

Nausea/vomiting:

Have the child take this medicine with or just after a meal or a snack. Let the child stick to simple meals and avoid having rich or spicy food.

Headache:

Ask the child to take rest and drink plenty of fluids. Headaches usually go away after first week of administration of CEPODEM XP 100 DRY SUSPENSION. If it lasts more than a week or becomes severe, then inform your doctor.

Diarrhoea: 

Ask the child to drink lots of fluids such as water or fruit juices so that the child is sufficiently hydrated. Do not administer any medicine to treat the condition on your own. Consult your doctor if the symptom does not improve or becomes worse.

WARNING & PRECAUTIONS

PREGNANCY

CEPODEM XP 100 DRY SUSPENSION is not recommended for use in pregnant women as it is used only in children.

BREASTFEEDING

CEPODEM XP 100 DRY SUSPENSION is not recommended for use in breastfeeding women as it is used only in children.

KIDNEY

CEPODEM XP 100 DRY SUSPENSION should be administered with caution in children with kidney problems such as mild, moderate, and severe renal impairment. Consult your doctor before administering CEPODEM XP 100 DRY SUSPENSION to the child.

LIVER

CEPODEM XP 100 DRY SUSPENSION should be administered with caution in children with liver problems such as hepatic impairment/insufficiency. Consult your doctor before administering CEPODEM XP 100 DRY SUSPENSION to the child.

ALLERGY

Do not administer CEPODEM XP 100 DRY SUSPENSION if the child is allergic to cefpodoxime, clavulanic acid, other cephalosporin group of antibiotics, and/or any other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug Interactions:

Before administering CEPODEM XP 100 DRY SUSPENSION, inform your doctor, if your child is taking any of the following medicine:

• antacids (medicines used to relieve indigestion and heartburn) Ex. sodium bicarbonate, aluminium hydroxide
• probenecid (used to treat gout)
• nephrotoxic drugs (medicines that can damage kidney via various mechanisms) Ex. aminoglycosides, amphotericin B.

Overdosage:

If the child or anyone else accidentally take too much of CEPODEM XP 100 DRY SUSPENSION, consult and inform your doctor immediately or visit the nearby hospital. The symptoms of overdosage of CEPODEM XP 100 DRY SUSPENSION may include nausea, vomiting, epigastric distress, and diarrhoea.

SYNOPSIS

MORE INFORMATION

•  Keep CEPODEM XP 100 DRY SUSPENSION out of reach of children
• Store CEPODEM XP 100 DRY SUSPENSION below 25°C

FAQs ABOUT CEPODEM XP 100 DRY SUSPENSION

What is CEPODEM XP 100 DRY SUSPENSION used for?

CEPODEM XP 100 DRY SUSPENSION is used in children to treat mild to moderate infections such as otitis media (middle ear infection), nose & throat infections, respiratory tract infection, urinary tract infection, reproductive tract infection, and skin infection.

How CEPODEM XP 100 DRY SUSPENSION works?

CEPODEM XP 100 DRY SUSPENSION helps to treat mild to moderate infections, where Cefpodoxime works by preventing the formation of the protective covering of the bacteria which is essential for the survival of bacteria and Clavulanic acid works by reducing the resistance and enhancing the activity of Cefpodoxime against bacteria thus preventing the occurrence of infections in affected children. 

What are the most common side effects of taking CEPODEM XP 100 DRY SUSPENSION?

The most common side effects of administering CEPODEM XP 100 DRY SUSPENSION in child are diarrhoea, nausea, vomiting, abdominal pain, headache, vaginal fungal infections, and/or vulvovaginal infections. Consult your doctor if any of these symptoms worsens.

Can CEPODEM XP 100 DRY SUSPENSION cause diarrhoea?

Yes, CEPODEM XP 100 DRY SUSPENSION causes diarrhoea as it is the most common side effect associated with the use of medicine. If such side effects experienced, then ask the child to drink lots of fluids such as water or fruit juices so that the child is sufficiently hydrated. Do not administer any medicine to treat the condition on your own. Consult your doctor if the symptom does not improve or becomes worse.

How CEPODEM XP 100 DRY SUSPENSION is administered in the child?

Administer CEPODEM XP 100 DRY SUSPENSION as advised by your physician. Shake the dry powder loose and reconstitute the dry powder in required quantity of water before consuming. Your doctor will decide the exact dose and duration of treatment for your child depending on child’s age, body weight and disease condition.

REFERENCES

1. K.D. Tripathi. Beta-Lactam Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 724 & 728.

2. P Gehanno, B Barry, S Bobin, C Safran. Twice daily cefpodoxime proxetil compared with thrice daily amoxicillin/clavulanic acid for treatment of acute otitis media in children. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in 1994] [Accessed on 7th July 2022] https://pubmed.ncbi.nlm.nih.gov/7855555/

3. CiplaMed. CEFOPROX CV Tablets. [Revised in October 2018] [Accessed on 7th July 2022] https://ciplamed.com/content/cefoprox-cv-tablets-suspension

4. Leeford Healthcare Limited. CEKODA CV DRY SYRUP. [Accessed on 7th July 2022] https://www.leeford.in/product/375/cekoda-cv-dry-syrup

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count
• Bacterial culture test

AUTHOR DETAILS

Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 02 Nov 2022 | 09:54 AM(IST)