INTRODUCTION

CARNITOR 500MG contains Levocarnitine which belongs to the group of medicines called amino acid derivatives. It is used to treat both primary and secondary carnitine deficiency in adults and in children. Carnitine is a natural substance acquired mostly through the diet and plays a substantial physiological role in mammalian energy metabolism. It is very essential for heart and brain function, muscle movement, and many other body processes.

Deficiency of carnitine leads to encephalopathy (severe brain dysfunction), cardiomyopathy (weakened and enlarged heart), vomiting, confusion, muscle weakness and decreased blood sugar levels. Levocarnitine tablets boosts the level of endogenous carnitine and give your body more energy.

The most common side effect of this medicine are GI disorders like nausea, vomiting, stomach pain and diarrhea. To avoid them, this medicine should be consumed at regular intervals evenly throughout the day. It is for oral use only. Avoid smoking and alcohol consumption while taking this medicine, because it can interfere with the effects of CARNITOR 500MG. Talk to your doctor before you are taking this medicine, if you have severe kidney problems. Before taking this medicine, inform your doctor if you are pregnant or breast feeding.

USES OF CARNITOR 500MG

• Treat primary and secondary carnitine deficiency

HOW CARNITOR 500MG WORKS

Levocarnitine works by facilitating the entry of long-chain fatty acid into cellular mitochondria, and results in subsequent energy production for proper metabolism. It also alleviates the metabolic abnormalities of patients with inborn errors that result in accumulation of toxic organic acids.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF CARNITOR 500MG

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine at regular intervals evenly throughout the day. Stick to simple meals. Do not eat rich or spicy food.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking:

• medicines that reduces blood clotting (e.g. warfarin)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT CARNITOR 500MG

Can CARNITOR 500MG be crushed?

Do not crush or chew the medicine. Swallow the medicine completely with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition.

Can CARNITOR 500MG cause diarrhea?

Yes. This medicine can cause diarrhea in some individuals, although not everybody gets them. Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Can CARNITOR 500MG be taken with warfarin?

No. Avoid concomitant use of this medicine with warfarin, because it can increase the blood clotting time.

REFERENCES

1. KD. Tripathi. Miscellaneous drugs. Vitamins. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 912.

2. ECOG-ACRIN Cancer Research Group. National Cancer Institute (NCI). Phase III Randomized Placebo-Controlled Trial to Determine Efficacy of Levocarnitine for Fatigue in Patients with Cancer. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on May 2016] [Accessed 5th November 2020] https://clinicaltrials.gov/ct2/show/NCT00091169

3. Roger Fielding, Linda Riede, James P. Lugo and Aouatef Bellamine. l-Carnitine Supplementation in Recovery after Exercise. NCBI; PMC US National Library of Medicine, National Institute of Health. March 2018. [Accessed 5th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872767/

4. Leadiant Bioscience. Carnitor.com. [Revised on April 2018] [Accessed 5th November 2020] http://www.carnitor.com/pdf/Carnitor-Tablets-OS-SF-PI-04.18-OPI.pdf

5. Sigma-tau Pharmaceuticals Inc. U.S. Food & Drug Administration. June 2006. [Accessed 5th November 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/018948s024,019257s011lbl.pdf

USEFUL DIAGNOSTIC TESTS

• Carnitine test – Blood test