CAPMIDE Capsule 4's

Cancer/Oncology Rx required

Best Price* ₹ 809.60 MRP ₹ 1,012.00
(Inclusive of all taxes) *4 Capsule(s) in a Strip * Mkt: Cipla Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

CAPMIDE contains Enzalutamide which belongs to the group of medicines called Androgen receptor inhibitors. It is used to treat adult men with prostate cancer that no longer responds to hormone therapy or surgical treatment or if the cancer despite responding to treatment has spread to other parts of the body. Prostate cancer occurs in the prostate gland (a gland in males that produces the seminal fluid to transport sperms). Symptoms include problem while urinating (difficulty, decreased force, or blood in urine), blood in the semen, bone pain, erectile dysfunction and weight loss.

Enzalutamide acts by blocking the activity of hormones called androgens (such as testosterone). By blocking androgens, it stops the growth of prostate cancer cells and can furhter induce cancer cell death and tumor regression.

Before taking CAPMIDE, inform your doctor if you have kidney problems, liver problems or heart conditions like arrhythmia (heart rhythm problem). CAPMIDE is not recommended for use in pregnant and breastfeeding women. CAPMIDE is not recommended for use in children and adolescents. Consult your doctor before taking it. The most common side effects of taking CAPMIDE are tiredness, broken bones, hot flushes, high blood pressure, headache, feeling anxious, dry skin, itching, difficulty remembering and breast enlargement in men.

USES OF CAPMIDE

  • Treats prostate cancer

HOW CAPMIDE WORKS

CAPMIDE works by blocking the activity of hormones called androgens (such as testosterone). By blocking androgens, it stops the growth of prostate cancer cells and can induce cancer cell death and tumor regression.

DIRECTIONS FOR USE

Take CAPMIDE as advised by your physician. Swallow it with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF CAPMIDE

COMMON

  • tiredness and falling
  • broken bones
  • hot flushes, high blood pressure, blockage of the arteries in the heart (ischemic heart disease)
  • headaches
  • feeling anxious, symptoms of restlessness
  • an uncontrollable urge to move a part of the body, usually the legs
  • dry skin and itching
  • difficulty remembering, reduced concentration, forgetfulness
  • change in sense of taste
  • breast enlargement in men (gynecomastia)

UNCOMMON

  • hallucinations
  • difficulty thinking clearly
  • low white blood cell count

RARE

  • posterior reversible encephalopathy syndrome (reversible condition involving the brain)

Stop taking and contact your doctor immediately if you experience,

  • seizures

HOW TO MANAGE SIDE EFFECTS

Headache:

Drink enough water and avoid bright lights. A cold compress will also give a soothing effect.

WARNING & PRECAUTIONS

PREGNANCY

CAPMIDE is not recommended for use in pregnant women. Consult your doctor before taking it. Women who are or may become pregnant should not handle broken or damaged medicine without wearing protection like gloves.

BREASTFEEDING

CAPMIDE is not recommended for breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES

CAPMIDE may have moderate influence on the ability to drive and use machines, so avoid driving or handling machines while on CAPMIDE.

KIDNEY

CAPMIDE should be taken with caution in patients with severe kidney disease. Consult your doctor before taking it.

LIVER

CAPMIDE should be used with caution in patients with severe liver disease. Consult your doctor before taking it.

ALLERGY

Do not take CAPMIDE if you are allergic to Enzalutamide.

HEART DISEASE

CAPMIDE should be taken with caution in patients with heart or blood vessel conditions, including heart rhythm problems (arrhythmia).Consult your doctor before taking it.

OTHERS

Before taking CAPMIDE, inform your doctor if you:

  • have seizures or fits

Use in pediatrics:

CAPMIDE is not recommended for use in children and adolescents. Consult your doctor before taking it.

Use in geriatrics:

Your doctor will give the right dose depending on your age, body weight and disease condition. Consult your doctor before taking CAPMIDE.

INTERACTIONS

A. Drug - Drug interactions:

Before taking CAPMIDE, inform your doctor if you are taking any of the following medicines:

  • anticoagulants (Ex. warfarin, acenocoumarol, clopidogrel)
  • to treat asthma and other respiratory diseases (Ex. aminophylline, theophylline).
  • to treat certain psychiatric disorders such as depression and schizophrenia (Ex.clozapine, olanzapine, chlorpromazine, mesoridazine, thioridazine, amitriptyline, desipramine, doxepin, imipramine, maprotiline, risperidone, ziprasidone, bupropion, lithium,mirtazapine, diazepam, midazolam, haloperidol)
  • to lower cholesterol (Ex. gemfibrozil, atorvastatin, simvastatin)
  • to treat pain (Ex. fentanyl, tramadol,pethidine, methadone)
  • to treat cancer (Ex.cabazitaxel,docetaxel)
  • to treat epilepsy (Ex. carbamazepine, clonazepam, phenytoin, primidone, valproic acid)
  • to treat sleep disorders (Ex. zolpidem)
  • to treat heart conditions or lower blood pressure (Ex. bisoprolol, digoxin, diltiazem, felodipine, nicardipine, nifedipine, propranolol, verapamil), to prevent heart conditions or strokes (Ex. dabigatran etexilate), to treat heart rhythm problems (Ex. quinidine, procainamide, amiodarone and sotalol)
  • to treat serious disease related to inflammation (Ex. dexamethasone, prednisolone)
  • to treat HIV infection (Ex. indinavir, ritonavir)
  • to treat bacterial infections (Ex. clarithromycin, doxycycline)
  • to treat thyroid disorders (Ex. levothyroxine)
  • to treat gout (Ex. colchicine)
  • to treat stomach disorders (Ex. omeprazole)
  • to prevent organ rejection (Ex. tacrolimus)
  • moxifloxacin (an antibiotic)

Overdosage:

If you or anyone else accidentally take too much of CAPMIDE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose is seizures.

SYNOPSIS

Drug :   Enzalutamide
Pharmacological Category :   Androgen receptor inhibitors
Therapeutic Indication :   Prostate cancer
Dosage Forms :   Capsule

MORE INFORMATION

  • Keep CAPMIDE out of reach of children
  • Store below 30°C

FAQs ABOUT CAPMIDE

Can CAPMIDE cause confusion?

Yes, CAPMIDE can develop a condition involving the brain called posterior reversible encephalopathy syndrome. If you have seizures, increasing headache, confusion, blindness, or vision problems, please contact your doctor as soon as possible.

What if I forget to take CAPMIDE?

If you forget to take CAPMIDE at the usual time, take it soon as you remember. If you forget it for the whole day, take it the following day. If you forget to take the medicine for more than one day, talk to your doctor immediately. Do not take a double dose.

Is CAPMIDE a chemotherapy drug?

No, CAPMIDE is not a chemotherapy drug despite being used to treat cancer. It is a type of hormone therapy that works to prevent prostate cancer cells from growing and spreading by blocking the action of a group of hormones called androgens.

Can CAPMIDE be taken by a woman?

No. CAPMIDE is not recommended for women. It is used to treat prostate cancer in men.

REFERENCES

1. Jean Hoffman, Wm Kevin Kelly. Enzalutamide: a novel antiandrogen for patients with castrate-resistant prostate cancer. [Revised on March 2013] [Accessed on 9th May 2022] https://pubmed.ncbi.nlm.nih.gov/23300275/

2. Astellas Pharma Europe B.V. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 9th May 2022] https://www.medicines.org.uk/emc/files/pil.10318.pdf

3. Enzalutamide. MayoClinic. [Revised on June 2021] [Accessed on 9th May 2022] https://www.mayoclinic.org/diseases-conditions/prostate-cancer/diagnosis-treatment/drc-20353093

USEFUL DIAGNOSTIC TESTS

  • Digital rectal exam (DRE)
  • Prostate-specific antigen (PSA) test
  • MRI scan
  • Ultrasound

PRODUCT DETAILS

    Net Qty
    1 N
    Ingredient
    ENZALUTAMIDE 40 mg
    Hsn Code
    30049049
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

CAPMIDE Capsule 4's

CAPMIDE Capsule 4's Mkt: Cipla Ltd

M.R.P.: Rs.1,012.00
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