INTRODUCTION
CANDO V 100MG TABLET contains Clotrimazole which belongs to the group of medicines called Antifungals. It is used in the treatment of candidal vaginitis. Candidal vaginitis is an infection caused by a type of fungi called yeast that affects the female genital organs such as the vagina and vulva the outer region of the vagina.
Candidal vaginitis causes itching in the vagina and areas surrounding it, abnormally smelly discharge, pain during intercourse, and painful urination. Pregnant women, women using contraceptives, women with weakened immune systems recently treated with antibiotics, and diabetic women are highly susceptible to this infection. Do not use tampons, intravaginal douches, spermicides, or other vaginal products while using CANDO V 100MG TABLET. Sexual intercourse should be avoided during the treatment.
CANDO V 100MG TABLET is not recommended for use in patients with irregular vaginal bleeding, abnormal vaginal bleeding like a blood discharge, ulcers, blisters, or sores in the vagina, lower stomach pain, fever, shivering, nausea, vomiting, diarrhoea, a smell in the vaginal discharge, or a menstrual period. CANDO V 100MG TABLET should be used with caution in patients who have had fungal infections twice in the last six months or who have ever had a sexually transmitted disease or had sexual contact with a patient who has a sexually transmitted disease.
In pregnant and breastfeeding women, CANDO V 100MG TABLET should be used with caution. Kindly consult your doctor before using it. CANDO V 100MG TABLET should not be used by children under the age of 16. In elderly patients over the age of 60, CANDO V 100MG TABLET should be used with caution. The common side effects of CANDO V 100MG TABLET are burning, stinging, swelling, and irritation sensations in the vagina.
USES OF CANDO V 100MG TABLET
- Treats candidal vaginitis
HOW CANDO V 100MG TABLET WORKS
CANDO V 100MG TABLET works by preventing fungal growth. Clotrimazole works by blocking the production of enzymes responsible for the growth of fungal cells. This inhibition results in the breakage of cell membranes and fungal cell abnormalities, finally leading to alterations in the membrane-based activity of fungus. These lead to fungal cell death and the prevention of further fungal growth.
DIRECTIONS FOR USE
Use CANDO V 100MG TABLET as advised by your physician. It is for vaginal use only. Do not swallow the medicine. CANDO V 100MG TABLET should be inserted into the vagina, as high as possible, using the applicator provided which is best achieved when lying back with legs bent up. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition. If you have any doubts regarding the doses, consult your doctor.
SIDE EFFECTS OF CANDO V 100MG TABLET
COMMON
- mild burning or irritation after inserting CANDO V 100MG TABLET
- skin peeling on genitals
- severe itching, rashes
- swelling of body parts
- discomfort, burning sensation, irritation, or pain in the pelvic region
- unusual vaginal bleeding, stomach pain
RARE
Stop using this medicine and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction symptoms include swelling of the lips, throat or tongue, difficulty in swallowing or breathing, weakness, feeling dizzy or faint, nausea, low blood pressure, rash
- intolerable itching, rash, swelling, redness, discomfort, burning, irritation, vaginal peeling, discharge or bleeding
- pain (Ex. abdominal pain, vulvovaginal pain)
HOW TO MANAGE SIDE EFFECTS
Stomach pain:
Some diet and lifestyle changes can help with stomach pain. Eat smaller portions of your meal. Chew your food well and eat slowly. Avoid foods that cause gas or indigestion. Avoid consuming alcohol and caffeine. Avoid sitting idle or lying down after having your meal; it’s better to go for a walk. If symptoms do not improve, consult your doctor.
WARNING & PRECAUTIONS
PREGNANCY
CANDO V 100MG TABLET should be used with caution in pregnant women or in women planning to have a baby under the supervision of a physician or midwife. During pregnancy, the tablet should be inserted without using an applicator. Consult your doctor before using it.
BREASTFEEDING
In breastfeeding women, CANDO V 100MG TABLET should be used with caution. Consult your doctor before using it.
DRIVING AND USING MACHINES
CANDO V 100MG TABLET has no or negligible effects on your ability to drive or use machines.
ALLERGY
Do not use CANDO V 100MG TABLET if you are allergic to clotrimazole or any other ingredients of this medicine.
OTHERS
Use in paediatrics:
CANDO V 100MG TABLET should be used with caution in children and adolescents below 16 years of age. Consult your doctor before using it.
Use in geriatrics:
CANDO V 100MG TABLET should be used with caution in elderly people above 60 years. Consult your doctor before taking it.
Others:
CANDO V 100MG TABLET is not recommended for use if you:
- have irregular vaginal bleeding
- have abnormal vaginal bleeding like a blood discharge
- have ulcers, blisters or sores in the vagina
- have lower stomach pain
- pain while passing urine
- have fever or shivering
- have nausea, vomiting
- have diarrhoea
- have smelled vaginal discharge
- have a menstrual period
Before taking CANDO V 100MG TABLET inform your doctor if you:
- have been diagnosed with fungal infections twice in the last six months
- have or ever had a sexually transmitted disease or had sexual contact with a sexually transmitted disease patient
INTERACTIONS
A. Drug-Drug interactions:
Before usingCANDO V 100MG TABLET, inform your doctor if you are taking any of the following medicine:
- medicines used after an organ transplant Ex. tacrolimus, sirolimus
- latex contraceptives (condoms or diaphragms) used for safe sex and to prevent pregnancy
Overdosage:
If you or anyone else accidentally used more of CANDO V 100MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms include dizziness, nausea or vomiting.
SYNOPSIS
| Drug | : | clotrimazole |
| Pharmacological Category | : | Imidazole |
| Therapeutic Indication | : | fungal infections |
| Dosage Forms | : | Vaginal tablet, cream, lotion, lozenges, soap, pessaries, spray, powder, paint, ointment, gel, ear drops |
MORE INFORMATION
- Keep CANDO V 100MG TABLET out of reach from children
- Store at room temperature
FAQs ABOUT CANDO V 100MG TABLET
Q: What is CANDO V 100MG TABLET used for?
A: CANDO V 100MG TABLET contains Clotrimazole, which belongs to the group of medicines called antifungals. It is used in the treatment of candidal vaginitis. Candidal vaginitis is an infection caused by yeast that affects the female genital organs such as the vagina and the vulva, which is the vagina's outer region. Candidal vaginitis causes itching in the vagina and areas surrounding it, abnormally smelly discharge, pain during intercourse, and painful urination. Pregnant women, women using contraceptives, women with weakened immune systems recently treated with antibiotics, and diabetic women are highly susceptible to this infection.
Q: How does CANDO V 100MG TABLET work?
A: CANDO V 100MG TABLET works by preventing the fungus' growth. Clotrimazole works by blocking the production of enzymes responsible for the growth of fungal cells. This inhibition results in the breakage of cell membranes and fungal cell abnormalities, finally leading to alterations in the membrane-based activity of fungus. These lead to fungal cell death and the prevention of further fungal growth.
Q: How should I use CANDO V 100MG TABLET?
A: Use CANDO V 100MG TABLET as advised by your physician. It is for vaginal use only. Do not swallow the medicine. Insert CANDO V 100MG TABLET inside your vagina as directed by your physician. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition. If you have any doubts regarding the doses, consult your doctor.
Q: Can I take CANDO V 100MG TABLET orally?
A: No, do not take CANDO V 100MG TABLET orally, as it is not intended to be taken orally; it should be inserted directly into the vagina. Consult your doctor before using it.
Q: What are the dos and don'ts while using CANDO V 100MG TABLET?
A: Do not use tampons, intravaginal douches, spermicides, or other vaginal products while using CANDO V 100MG TABLET. Sexual intercourse should be avoided as your partner is at risk of infection. Avoid concomitant use of tacrolimus and condoms while on treatment with CANDO V 100MG TABLET.
Q: Can I use CANDO V 100MG TABLET during my menstrual cycle?
A: No, do not use CANDO V 100MG TABLET during my menstrual cycle as there is a high risk that the medicine will be washed out. Treatment should be completed before the onset of the menstrual cycle or after the menstrual cycle.
Q: What are the side effects of CANDO V 100MG TABLET?
A: The common side effects of CANDO V 100MG TABLET are burning, itching, and irritation sensations in the vagina and skin. Peeling in the genital area, severe itching, rashes, swelling of body parts, discomfort, burning sensation, irritation, or pain in the pelvic region, unusual vaginal bleeding, and stomach pain
Q: Will CANDO V 100MG TABLET cause stomach pain?
A: Stomach pain is the most common side effect of CANDO V 100MG TABLET. Some diet and lifestyle changes can help with stomach pain. Eat smaller portions of your meal. Chew your food well and eat slowly. Avoid foods that cause gas or indigestion. Avoid consuming alcohol and caffeine. Avoid sitting idle or lying down after having your meal; it’s better to go for a walk.
Q: Can CANDO V 100MG TABLET be used during pregnancy?
A: CANDO V 100MG TABLET should be used with caution in pregnant women or in women planning to have a baby under the supervision of a physician or midwife. During pregnancy, the tablet should be inserted without using an applicator. Consult your doctor before using it.
REFERENCES
1. KD Tripathi, Antimicrobial Drugs Essentials of pharmacology, seventh edition, 2013 page no- 792.
2. Werner Mendling, Maged Atef El Shazly, and Lei Zhang Clotrimazole for Vulvovaginal Candidosis: More Than 45 Years of Clinical Experience September 2020 NCBI, PMC US National Library of Medicine, National Institute of Health. [Accessed on 18th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600851/#__ffn_sectitle
3. Tillomed Laboratories Ltd Electronic Medicines Compendium (EMC). Clotrimazole. [Revised in December 2020] [Accessed on 18th July 2022] https://www.medicines.org.uk/emc/files/pil.11464.pdf
4. GP Grenzach Produktions GmbH. Electronic Medicines Compendium (EMC). Canesten 100mg. [Revised on February 2021] [Accessed on 18th July 2022] https://www.medicines.org.uk/emc/files/pil.2203.pdf
5. Glenmark Pharmaceuticals Limited U.S. Food & Drug Administration. Candid V6. [Revised on November 2017] [Accessed on 18th July 2022] https://fdaghana.gov.gh/img/smpc/Candid%20V6%20100mg%20Vaginal%20Tablets%20(Clotrimazole).pdf
6. Torque pharma. Clotrimazole 100mg. [Accessed on 18th July 2022] https://www.torquepharma.com/fungnil-v-tablets/
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