INTRODUCTION

CANDIZEST CT SOFTGEL is a combination of Clindamycin, Clotrimazole, and Tinidazole which belongs to the group of medicines called Antibiotics, Antifungals, and Antiprotozoals respectively. It is used to treat vaginal infections caused by fungus alone or secondarily infected with bacteria.

Fungal vaginal infections often involve both the vulva and the vagina, with symptoms like intense vulvar itching, soreness, irritation, burning while urinating, pain, redness, curdy cheese like discharge, small injuries, and swelling.

Before using CANDIZEST CT SOFTGEL, inform your doctor if you have any problems with formation of blood clots or fits. Consult your doctor for advice.

CANDIZEST CT SOFTGEL is not recommended for use in first trimester of pregnancy and should be used with caution in rest of the pregnancy, and in breastfeeding women. Consult your doctor for advice before using.

The most common side effects of using CANDIZEST CT SOFTGEL are loss of appetite, bitter taste, nausea, vomiting, diarrhea, extreme tiredness, dry mouth, stomach distress, and headache. Contact your doctor if any of above the side effects worsen.

USES OF CANDIZEST CT SOFTGEL

• Used to treat vaginal infections

HOW CANDIZEST CT SOFTGEL WORKS

CANDIZEST CT SOFTGEL works by stopping the growth of infecting fungus where Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit and directly preventing the formation of bacterial protein. Clotrimazole inhibits the synthesis of a substance (ergosterol), which is an integral part of the cell membrane, thus impairing the fungal cell membrane, and Tinidazole releases certain unstable molecules (free radicals) during cell metabolism that bind to DNA, damage it, and results in cell death.

DIRECTIONS FOR USE

Use CANDIZEST CT SOFTGEL as advised by your physician. It is for vaginal use only. Check the label for directions before use. Wash and dry your vaginal area and lie on your back and gently insert the medicine into the vagina as high as possible with or without the use of an applicator as mentioned in the label. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of infection.

SIDE EFFECTS OF CANDIZEST CT SOFTGEL

HOW TO MANAGE SIDE EFFECTS

Nausea or Vomiting:

Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. Get adequate rest. Drink lots of fluids, especially water. Do not take any medicine for nausea or vomiting without asking the doctor.  

Headache:

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache. If headache does not improve, contact your doctor.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If diarrhea does not improve, contact your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before using CANDIZEST CT SOFTGEL, inform your doctor if you are using, have used, or might use any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

If you or anyone else accidentally uses too much of CANDIZEST CT SOFTGEL, contact your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep CANDIZEST CT SOFTGEL out of reach of children
• Store below 30°C

FAQs ABOUT CANDIZEST CT SOFTGEL

Q: What if I forget to use a dose of CANDIZEST CT SOFTGEL?

A: If you forget to use a dose of CANDIZEST CT SOFTGEL, use it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not use CANDIZEST CT SOFTGEL twice to make up for a forgotten dose. If you have any more doubts regarding the use of CANDIZEST CT SOFTGEL, ask your doctor.

Q: Does CANDIZEST CT SOFTGEL cause vomiting?

A: Vomiting is a common side effect of CANDIZEST CT SOFTGEL. In such cases, get adequate rest and drink lots of fluids, especially water. Have small sips if you feel sick. Do not take any medicine for vomiting without asking your doctor. Tell your doctor if you have continuous vomiting.

Q: What precautions do I need to follow while using CANDIZEST CT SOFTGEL?

A: Patients using CANDIZEST CT SOFTGEL must inform their doctor about their pre-existing disease conditions like blood cell formation problems, low neutrophil count, or fits. Contact your doctor immediately if you have any unusual symptoms.

Q: Can CANDIZEST CT SOFTGEL be used in pregnancy?

A: CANDIZEST CT SOFTGEL is not recommended for use in first trimester of pregnancy. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before using CANDIZEST CT SOFTGEL. Inform your doctor immediately if you become pregnant during treatment with CANDIZEST CT SOFTGEL.

Q: Does CANDIZEST CT SOFTGEL cause headache?

A: Headache is a common side effect of CANDIZEST CT SOFTGEL. In such case, drink ample amount of water and get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache. If symptom does not improve, contact your doctor.

REFERENCES

1. Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey. Superficial Fungal Infections. Pharmacotherapy- A Pathophysiologic Approach. Eighth edition. Page-2056.

2. M. Maladkar, C. Tekchandani, U. Dave. Clindamycin, Clotrimazole and Tinidazole in Mixed Vaginosis- A “Real World” Clinical Experience. Journal of Gynecology and Obstetrics. January 2015. [Accessed on 24th June 2022] https://www.researchgate.net/publication/284617556_Clindamycin_Clotrimazole_and_Tinidazole_in_Mixed_Vaginosis-A_Real_World_Clinical_Experience

3. DM Pharma. Clindamycin + Clotrimazole +Tinidazole. [Accessed on 24th June 2022] https://www.dmpharma.co.in/Clindamycin%20Phosphate,%20Clotrimazole%20and%20Tinidazole%20Soft%20Gelatin%20Capsules.html

USEFUL DIAGNOSTIC TESTS

• Pelvic exam