CALSPRAY Spray inhaler/injection/nasal spray is used for the treatment of osteoporosis in post-menopausal women.

CALSPRAY Spray may also be prescribed for other conditions as determined by the doctor.

CALSPRAY Spray belongs to the class of drugs called hormones. The drug acts by binding to certain receptors in the body, which enhances the enzymes to improve and maintain the calcium levels in the blood. Thus, it decreases the bone loss process.

The dosage and the drug form depend on the age, weight and medical condition of an individual. Use CALSPRAY Spray inhaler/injection/nasal spray as prescribed by your doctor.

• Remove the cap and shake the inhaler Hold the inhaler in front of the mouth and breathe in slowly. Press the inhaler one time and breathe as deeply as you can.
• CALSPRAY Spray injection should be administered only under medical supervision.
• Please follow the instruction provided on the leaflet while using this nasal spray .

If you miss a dose of CALSPRAY Spray, please use it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

The overdose symptoms of CALSPRAY Spray include the following:

• Nausea
• Vomiting

You must seek immediate medical care if you experience any of the above symptoms.

Drugs that interact with CALSPRAY Spray include the following:

• Etelcalcetide
• Lithium
• Zoledronic acid

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

The following are the most common side effects of CALSPRAY Spray:

• Nausea
• Vomiting
• Abdominal pain
• Diarrhoea
• Swelling at the injection site
• Flushing
• Blurred vision

The following are the severe side effects and you may require immediate medical attention:

• Increased urination
• Salty taste in the mouth
• Muscle cramps
• Numbness
• Swelling of ankles

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

• Avoid using the medicine if you are allergic to CALSPRAY Spray or similar drugs.
• Avoid consumption of alcohol as it may alter the absorption of CALSPRAY Spray.
• Do not drive or operate heavy machinery if CALSPRAY Spray causes dizziness or blurred vision.
• Avoid CALSPRAY Spray during pregnancy or breastfeeding because the safe use of the drug is not yet established.
• Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
• Keep the medication out of reach of children.

You are advised not to use CALSPRAY Spray if

• it has passed the expiry date of the medicine printed on the pack.
• the foil or packaging is torn or shows signs of tampering or there is discolouration.

• Tell your doctor if you have any history of liver, kidney, heart or respiratory diseases.
• Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• Notify your doctor if you get pregnant while using CALSPRAY Spray.

1. How should CALSPRAY Spray injection be stored?

CALSPRAY Spray injection should be stored in a refrigerator, but do not freeze the medication.

2. Should I follow any special dietary instructions while using CALSPRAY Spray?

Yes. It is advised to include a diet rich in calcium and vitamin D while using CALSPRAY Spray.

3. Is it common to experience joint pain while using CALSPRAY Spray?

No. Joint pain is one of the severe side effects of CALSPRAY Spray. Consult your doctor immediately on experiencing such symptoms.